Cytochrome P450 and matrix metalloproteinase genetic modifiers of disease severity in Cerebral Cavernous Malformation type 1

Title

Cytochrome P450 and matrix metalloproteinase genetic modifiers of disease severity in Cerebral Cavernous Malformation type 1

Authors

Keywords

Cerebrovascular disease, Cerebral Cavernous Malformation (CCM), Familial Cerebral Cavernous Malformation type 1, KRIT1/CCM1, Disease severity, Vascular brain lesions, Intracerebral hemorrhage, Inter-individual variability in disease susceptibility and outcome, Oxidative stress, Reactive oxygen species (ROS), Free radicals, Cytochrome P450 (CYP), Matrix metalloproteinase (MMP), Genetic markers set association study

Journal

FREE RADICAL BIOLOGY AND MEDICINE

Volume 92, Issue -, Pages 100-109

Publisher

Elsevier BV

Online

2016-01-19

DOI

10.1016/j.freeradbiomed.2016.01.008