Activating a DNA Nanomachine via Computation across Cancer Cell Membranes for Precise Therapy of Solid Tumors

Upconversion Luminescence-Controlled DNA Computation for Spatiotemporally Resolved, Multiplexed Molecular Imaging

(2021) Yongsheng Mi et al.   ANALYTICAL CHEMISTRY

Molecular Identification of Tumor-Derived Extracellular Vesicles Using Thermophoresis-Mediated DNA Computation

(2021) Yike Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Assembly Pathway Selection with DNA Reaction Circuits for Programming Multiple Cell–Cell Interactions

(2021) Mingshu Xiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Activatable Photodynamic Therapy with Therapeutic Effect Prediction Based on a Self-correction Upconversion Nanoprobe

(2020) Yuyi Li et al.   ACS Applied Materials & Interfaces

Ribbon of DNA Lattice on Gold Nanoparticles for Selective Drug Delivery to Cancer Cells

(2020) Shuxin Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cancer diagnosis with DNA molecular computation

(2020) Chao Zhang et al.   Nature Nanotechnology

DNA-Based Nanostructures for Live-Cell Analysis

(2020) Sasha B. Ebrahimi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An orthogonally regulatable DNA nanodevice for spatiotemporally controlled biorecognition and tumor treatment

(2020) Zhenghan Di et al.   Science Advances

A Near‐Infrared Photo‐Switched MicroRNA Amplifier for Precise Photodynamic Therapy of Early‐Stage Cancers

(2020) Yue Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A tubular DNA nanodevice as a siRNA/chemo‐drug co‐delivery vehicle for combined cancer therapy

(2020) Zhaoran Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A NIR Light Gated DNA Nanodevice for Spatiotemporally Controlled Imaging of MicroRNA in Cells and Animals

(2019) Jian Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Near-infrared Light-Initiated Hybridization Chain Reaction for Spatially- and Temporally-Resolved Signal Amplification

(2019) Hongqian Chu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Boosting Luminance Energy Transfer Efficiency in Upconversion Nanoparticles with an Energy-Concentrating Zone

(2019) Xiaobo Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices

(2019) Hongqian Chu et al.   Nature Communications

Construction of a Multiple-Aptamer-Based DNA Logic Device on Live Cell Membranes via Associative Toehold Activation for Accurate Cancer Cell Identification

(2019) Xu Chang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Overcoming the Reticuloendothelial System Barrier to Drug Delivery with a “Don’t-Eat-Us” Strategy

(2019) Yixuan Tang et al.   ACS Nano

Logic-Gate-Actuated DNA-Controlled Receptor Assembly for the Programmable Modulation of Cellular Signal Transduction

(2019) Shan Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A DNA-Azobenzene Nanopump Fueled by Upconversion Luminescence for Controllable Intracellular Drug Release

(2019) Yue Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Programming DNA-Based Biomolecular Reaction Networks on Cancer Cell Membranes

(2019) Tianqi Song et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Optical imaging and pH-awakening therapy of deep tissue cancer based on specific upconversion nanophotosensitizers

(2019) Yansong Feng et al.   BIOMATERIALS

Time-Resolved Activation of pH Sensing and Imaging in Vivo by a Remotely Controllable DNA Nanomachine

(2019) Jian Zhao et al.   NANO LETTERS

Photo-tearable tape close-wrapped upconversion nanocapsules for near-infrared modulated efficient siRNA delivery and therapy

(2018) Yue Zhang et al.   BIOMATERIALS

DNA Nanotechnology-Enabled Drug Delivery Systems

(2018) Qinqin Hu et al.   CHEMICAL REVIEWS

Upconversion Luminescence-Activated DNA Nanodevice for ATP Sensing in Living Cells

(2018) Jian Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nongenetic Approach for Imaging Protein Dimerization by Aptamer Recognition and Proximity-Induced DNA Assembly

(2018) Hong Liang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Engineering a 3D DNA-Logic Gate Nanomachine for Bispecific Recognition and Computing on Target Cell Surfaces

(2018) Ruizi Peng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photoactivated Specific mRNA Detection in Single Living Cells by Coupling “Signal-on” Fluorescence and “Signal-off” Electrochemical Signals

(2018) Fujian Huang et al.   NANO LETTERS

In Situ SiRNA Assembly in Living Cells for Gene Therapy with MicroRNA Triggered Cascade Reactions Templated by Nucleic Acids

(2018) Kewei Ren et al.   ACS Nano

Aptamer-integrated DNA nanostructures for biosensing, bioimaging and cancer therapy

(2016) Hong-Min Meng et al.   CHEMICAL SOCIETY REVIEWS

A DNA dual lock-and-key strategy for cell-subtype-specific siRNA delivery

(2016) Kewei Ren et al.   Nature Communications

Binding-Induced DNA Nanomachines Triggered by Proteins and Nucleic Acids

(2015) Hongquan Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cocoon-Like Self-Degradable DNA Nanoclew for Anticancer Drug Delivery

(2014) Wujin Sun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cell Membrane-Anchored Biosensors for Real-Time Monitoring of the Cellular Microenvironment

(2014) Liping Qiu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Powering the programmed nanostructure and function of gold nanoparticles with catenated DNA machines

(2013) Johann Elbaz et al.   Nature Communications

Fabricating a Reversible and Regenerable Raman-Active Substrate with a Biomolecule-Controlled DNA Nanomachine

(2012) Jing Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Near-infrared light induced in vivo photodynamic therapy of cancer based on upconversion nanoparticles

(2011) Chao Wang et al.   BIOMATERIALS