Depsipeptide Nucleic Acids: Prebiotic Formation, Oligomerization, and Self-Assembly of a New Proto-Nucleic Acid Candidate

X-ray Fiber Diffraction and Computational Analyses of Stacked Hexads in Supramolecular Polymers: Insight into Self-Assembly in Water by Prospective Prebiotic Nucleobases

(2021) Asem Alenaizan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemistry of Abiotic Nucleotide Synthesis

(2020) Mahipal Yadav et al.   CHEMICAL REVIEWS

Spontaneous Emergence of Self-Replicating Molecules Containing Nucleobases and Amino Acids

(2020) Bin Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Prebiotic Syntheses of Noncanonical Nucleosides and Nucleotides

(2020) David M. Fialho et al.   CHEMICAL REVIEWS

The Unexpected Base‐Pairing Behavior of Cyanuric Acid in RNA and Ribose versus Cyanuric Acid Induced Helicene Assembly of Nucleic Acids: Implications for the Pre‐RNA Paradigm

(2020) Brooke A. Anderson et al.   CHEMISTRY-A EUROPEAN JOURNAL

Noncovalent Helicene Structure between Nucleic Acids and Cyanuric Acid

(2020) Asem Alenaizan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organometallic compounds as carriers of extraterrestrial cyanide in primitive meteorites

(2019) Karen E. Smith et al.   Nature Communications

Nitrogen heterocycles form peptide nucleic acid precursors in complex prebiotic mixtures

(2019) Laura E. Rodriguez et al.   Scientific Reports

Unified prebiotically plausible synthesis of pyrimidine and purine RNA ribonucleotides

(2019) Sidney Becker et al.   SCIENCE

Eighty routes to a ribonucleotide world; dispersion and stringency in the decisive selection

(2018) Michael Yarus   RNA

Wet-dry cycles enable the parallel origin of canonical and non-canonical nucleosides by continuous synthesis

(2018) Sidney Becker et al.   Nature Communications

Experimentally investigating the origin of DNA/RNA on early Earth

(2018) Ramanarayanan Krishnamurthy   Nature Communications

Searching for lost nucleotides of the pre-RNA World with a self-refining model of early Earth

(2018) Nicholas V. Hud   Nature Communications

Elongation of Model Prebiotic Proto-Peptides by Continuous Monomer Feeding

(2017) Sheng-Sheng Yu et al.   MACROMOLECULES

Phosphorylation, oligomerization and self-assembly in water under potential prebiotic conditions

(2017) Clémentine Gibard et al.   Nature Chemistry

Nucleotide Selectivity in Abiotic RNA Polymerization Reactions

(2017) Kristin M. Coari et al.   ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES

Prebiotic stereoselective synthesis of purine and noncanonical pyrimidine nucleotide from nucleobases and phosphorylated carbohydrates

(2017) Hyo-Joong Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Divergent prebiotic synthesis of pyrimidine and 8-oxo-purine ribonucleotides

(2017) Shaun Stairs et al.   Nature Communications

Darwin's Warm Little Pond: A One-Pot Reaction for Prebiotic Phosphorylation and the Mobilization of Phosphate from Minerals in a Urea-Based Solvent

(2016) Bradley Burcar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reprogramming the assembly of unmodified DNA with a small molecule

(2016) Nicole Avakyan et al.   Nature Chemistry

Formation of supramolecular assemblies and liquid crystals by purine nucleobases and cyanuric acid in water: implications for the possible origins of RNA

(2016) C. Li et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Kinetics of prebiotic depsipeptide formation from the ester–amide exchange reaction

(2016) Sheng-Sheng Yu et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

A high-yielding, strictly regioselective prebiotic purine nucleoside formation pathway

(2016) S. Becker et al.   SCIENCE

Spontaneous formation and base pairing of plausible prebiotic nucleotides in water

(2016) Brian J. Cafferty et al.   Nature Communications

Ester-Mediated Amide Bond Formation Driven by Wet-Dry Cycles: A Possible Path to Polypeptides on the Prebiotic Earth

(2015) Jay G. Forsythe et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Was a Pyrimidine-Pyrimidine Base Pair the Ancestor of Watson-Crick Base Pairs? Insights from a Systematic Approach to the Origin of RNA

(2015) Brian J. Cafferty et al.   ISRAEL JOURNAL OF CHEMISTRY

On the formation of pyridine in the interstellar medium

(2015) Dorian S. N. Parker et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Ester Formation and Hydrolysis during Wet–Dry Cycles: Generation of Far-from-Equilibrium Polymers in a Model Prebiotic Reaction

(2014) Irena Mamajanov et al.   MACROMOLECULES

A self-replicating peptide nucleic acid

(2014) Tobias A. Plöger et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Ultra-sensitive pH control of supramolecular polymers and hydrogels: pKa matching of biomimetic monomers

(2014) B. J. Cafferty et al.   Chemical Science

The “Strong” RNA World Hypothesis: Fifty Years Old

(2013) Marc Neveu et al.   ASTROBIOLOGY

The Origin of RNA and “My Grandfather’s Axe”

(2013) Nicholas V. Hud et al.   CHEMISTRY & BIOLOGY

Spontaneous Prebiotic Formation of a β-Ribofuranoside That Self-Assembles with a Complementary Heterocycle

(2013) Michael C. Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient Self-Assembly in Water of Long Noncovalent Polymers by Nucleobase Analogues

(2013) Brian J. Cafferty et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Functional RNAs exhibit tolerance for non-heritable 2′–5′ versus 3′–5′ backbone heterogeneity

(2013) Aaron E. Engelhart et al.   Nature Chemistry

Potential Pitfalls in MALDI-TOF MS Analysis of Abiotically Synthesized RNA Oligonucleotides

(2013) Bradley T. Burcar et al.   ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES

Role of pKa of Nucleobases in the Origins of Chemical Evolution

(2012) Ramanarayanan Krishnamurthy   ACCOUNTS OF CHEMICAL RESEARCH

Universal Sequence Replication, Reversible Polymerization and Early Functional Biopolymers: A Model for the Initiation of Prebiotic Sequence Evolution

(2012) Sara Imari Walker et al.   PLoS One

Progress in demonstrating total homochiral selection in montmorillonite-catalyzed RNA synthesis

(2011) Prakash C. Joshi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Determinants of Cyanuric Acid and Melamine Assembly in Water

(2011) Mingming Ma et al.   LANGMUIR

May Cyclic Nucleotides Be a Source for Abiotic RNA Synthesis?

(2011) Giovanna Costanzo et al.   ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES

The Organic Composition of Carbonaceous Meteorites: The Evolutionary Story Ahead of Biochemistry

(2010) S. Pizzarello et al.   Cold Spring Harbor Perspectives in Biology

Mapping the Landscape of Potentially Primordial Informational Oligomers: Oligo-dipeptides Tagged with Orotic Acid Derivatives as Recognition Elements

(2009) Xuejun Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Thermal Wet Decomposition of Prussian Blue: Implications for Prebiotic Chemistry

(2009) Marta Ruiz-Bermejo et al.   CHEMISTRY & BIODIVERSITY

Synthesis of Pyrimidines and Triazines in Ice: Implications for the Prebiotic Chemistry of Nucleobases

(2009) César Menor-Salván et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions

(2009) Matthew W. Powner et al.   NATURE

Nucleobase-Directed Amyloid Nanotube Assembly

(2008) Peng Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY