Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis β-oxidation trifunctional enzyme

IceBear: an intuitive and versatile web application for research-data tracking from crystallization experiment to PDB deposition

(2021) Ed Daniel et al.   Acta Crystallographica Section D-Structural Biology

Insights into the stability and substrate specificity of the E. coli aerobic β-oxidation trifunctional enzyme complex

(2020) Shiv K. Sah-Teli et al.   JOURNAL OF STRUCTURAL BIOLOGY

Post-translational Succinylation of Mycobacterium tuberculosis Enoyl-CoA Hydratase EchA19 Slows Catalytic Hydration of Cholesterol Catabolite 3-Oxo-chol-4,22-diene-24-oyl-CoA

(2020) Amber C. Bonds et al.   ACS Infectious Diseases

Crystallographic binding studies of rat peroxisomal multifunctional enzyme type 1 with 3-ketodecanoyl-CoA: capturing active and inactive states of its hydratase and dehydrogenase catalytic sites

(2020) Shruthi Sridhar et al.   Acta Crystallographica Section D-Structural Biology

Crystal structure of Mycobacterium tuberculosis FadB2 implicated in mycobacterial β-oxidation

(2019) Jonathan A. G. Cox et al.   Acta Crystallographica Section D-Structural Biology

Crystal structure of human mitochondrial trifunctional protein, a fatty acid β-oxidation metabolon

(2019) Chuanwu Xia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The genetic requirements of fatty acid import by Mycobacterium tuberculosis within macrophages

(2019) Evgeniya V Nazarova et al.   eLife

Complementary substrate specificity and distinct quaternary assembly of the Escherichia coli aerobic and anaerobic β-oxidation trifunctional enzyme complexes

(2019) Shiv K. Sah-Teli et al.   BIOCHEMICAL JOURNAL

The EMBL-EBI search and sequence analysis tools APIs in 2019

(2019) Fábio Madeira et al.   NUCLEIC ACIDS RESEARCH

Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix

(2019) Dorothee Liebschner et al.   Acta Crystallographica Section D-Structural Biology

Cryo-EM structure of human mitochondrial trifunctional protein

(2018) Kai Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CCP4i2: the new graphical user interface to the CCP4 program suite

(2018) Liz Potterton et al.   Acta Crystallographica Section D-Structural Biology

DIALS: implementation and evaluation of a new integration package

(2018) Graeme Winter et al.   Acta Crystallographica Section D-Structural Biology

The peroxisomal zebrafish SCP2-thiolase (type-1) is a weak transient dimer as revealed by crystal structures and native mass spectrometry

(2018) Tiila-Riikka Kiema et al.   BIOCHEMICAL JOURNAL

Catabolism of the Cholesterol Side Chain in Mycobacterium tuberculosis Is Controlled by a Redox-Sensitive Thiol Switch

(2017) Rui Lu et al.   ACS Infectious Diseases

FLEXc: protein flexibility prediction using context-based statistics, predicted structural features, and sequence information

(2016) Ashraf Yaseen et al.   BMC BIOINFORMATICS

XDSAPP2.0

(2016) Karine M. Sparta et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Unsaturated Lipid Assimilation by Mycobacteria Requires Auxiliary cis-trans Enoyl CoA Isomerase

(2015) Sonali Srivastava et al.   CHEMISTRY & BIOLOGY

ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB

(2015) James A. Maier et al.   Journal of Chemical Theory and Computation

FadA5 a Thiolase from Mycobacterium tuberculosis : A Steroid-Binding Pocket Reveals the Potential for Drug Development against Tuberculosis

(2015) Christin M. Schaefer et al.   STRUCTURE

Increasing the structural coverage of tuberculosis drug targets

(2015) Loren Baugh et al.   TUBERCULOSIS

Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum

(2015) Sangwoo Kim et al.   Nature Communications

Pathogen roid rage: Cholesterol utilization byMycobacterium tuberculosis

(2014) Matthew F. Wipperman et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

Phylogenetic relationships and classification of thiolases and thiolase-like proteins of Mycobacterium tuberculosis and Mycobacterium smegmatis

(2014) Padmanabhan Anbazhagan et al.   TUBERCULOSIS

Structure of Mycobacterial β-Oxidation Trifunctional Enzyme Reveals Its Altered Assembly and Putative Substrate Channeling Pathway

(2013) Rajaram Venkatesan et al.   ACS Chemical Biology

How good are my data and what is the resolution?

(2013) Philip R. Evans et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The isomerase and hydratase reaction mechanism of the crotonase active site of the multifunctional enzyme (type-1), as deduced from structures of complexes with 3S-hydroxy-acyl-CoA

(2013) Prasad Kasaragod et al.   FEBS Journal

IntracellularMycobacterium tuberculosisExploits Host-derived Fatty Acids to Limit Metabolic Stress

(2013) Wonsik Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

XDSAPP: a graphical user interface for the convenient processing of diffraction data usingXDS

(2012) Michael Krug et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

An overview of the Amber biomolecular simulation package

(2012) Romelia Salomon-Ferrer et al.   Wiley Interdisciplinary Reviews-Computational Molecular Science

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Presenting your structures: theCCP4mgmolecular-graphics software

(2011) S. McNicholas et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Automated data collection for macromolecular crystallography

(2011) Graeme Winter et al.   METHODS

R.E.D. Server: a web service for deriving RESP and ESP charges and building force field libraries for new molecules and molecular fragments

(2011) Enguerran Vanquelef et al.   NUCLEIC ACIDS RESEARCH

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Peroxisomal Plant 3-Ketoacyl-CoA Thiolase Structure and Activity Are Regulated by a Sensitive Redox Switch

(2010) Valerie E. Pye et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of Liganded Rat Peroxisomal Multifunctional Enzyme Type 1

(2010) Prasad Kasaragod et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transient Protein-Protein Interactions: Structural, Functional, and Network Properties

(2010) James R. Perkins et al.   STRUCTURE

Molecular replacement withMOLREP

(2009) Alexei Vagin et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

xia2: an expert system for macromolecular crystallography data reduction

(2009) G. Winter   JOURNAL OF APPLIED CRYSTALLOGRAPHY

EDNA: a framework for plugin-based applications applied to X-ray experiment online data analysis

(2009) Marie-Françoise Incardona et al.   JOURNAL OF SYNCHROTRON RADIATION