Heterogenous presence of neutrophil extracellular traps in human solid tumours is partially dependent on IL ‐8

The mutational load and a T-cell inflamed tumour phenotype identify ovarian cancer patients rendering tumour-reactive T cells from PD-1+ tumour-infiltrating lymphocytes

(2021) Diego Salas-Benito et al.   BRITISH JOURNAL OF CANCER

Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis

(2021) Chang Cui et al.   CELL

Differential Interleukin‐8 thresholds for chemotaxis and netosis in human neutrophils

(2021) Alvaro Teijeira et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity

(2020) Álvaro Teijeira et al.   IMMUNITY

Elevated serum interleukin-8 is associated with enhanced intratumor neutrophils and reduced clinical benefit of immune-checkpoint inhibitors

(2020) Kurt A. Schalper et al.   NATURE MEDICINE

High systemic and tumor-associated IL-8 correlates with reduced clinical benefit of PD-L1 blockade

(2020) Kobe C. Yuen et al.   NATURE MEDICINE

Phosphatidylserine-exposing blood cells, microparticles and neutrophil extracellular traps increase procoagulant activity in patients with pancreatic cancer

(2020) Muxin Yu et al.   THROMBOSIS RESEARCH

Diverse immune environments in human lung tuberculosis granulomas assessed by quantitative multiplexed immunofluorescence

(2020) Marta Abengozar-Muela et al.   MODERN PATHOLOGY

DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25

(2020) Linbin Yang et al.   NATURE

Diagnostic, Therapeutic Predictive, and Prognostic Value of Neutrophil Extracellular Traps in Patients With Gastric Adenocarcinoma

(2020) Yiyin Zhang et al.   Frontiers in Oncology

Interleukin-17–induced neutrophil extracellular traps mediate resistance to checkpoint blockade in pancreatic cancer

(2020) Yu Zhang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Emerging Role of Neutrophil Extracellular Traps (NETs) in Tumor Progression and Metastasis

(2020) Maria Teresa Masucci et al.   Frontiers in Immunology

Interleukin-8, Neutrophils, and NETs in a Collusion against Cancer Immunity and Immunotherapy

(2020) Alvaro Teijeira et al.   CLINICAL CANCER RESEARCH

Identification of mutations associated with acquired resistance to sunitinib in renal cell-cancer

(2019) Mohamed Elgendy et al.   INTERNATIONAL JOURNAL OF CANCER

Citrullinated histone H3, a biomarker for neutrophil extracellular trap formation, predicts the risk of mortality in patients with cancer

(2019) Ella Grilz et al.   BRITISH JOURNAL OF HAEMATOLOGY

Expression analysis and significance of PD-1, LAG-3 and TIM-3 in human non-small cell lung cancer using spatially-resolved and multiparametric single-cell analysis.

(2019) Ila J Datar et al.   CLINICAL CANCER RESEARCH

Neutrophils and neutrophil extracellular traps enhance venous thrombosis in mice bearing human pancreatic tumors

(2019) Yohei Hisada et al.   HAEMATOLOGICA

Cancer cell–induced neutrophil extracellular traps promote both hypercoagulability and cancer progression

(2019) Hye Soo Jung et al.   PLoS One

Neutrophil Extracellular Traps Initiate Gallstone Formation

(2019) Luis E. Muñoz et al.   IMMUNITY

Phase I trial of HuMax-IL8 (BMS-986253), an anti-IL-8 monoclonal antibody, in patients with metastatic or unresectable solid tumors

(2019) Marijo Bilusic et al.   Journal for ImmunoTherapy of Cancer

Immune effector monocyte–neutrophil cooperation induced by the primary tumor prevents metastatic progression of breast cancer

(2019) Catharina Hagerling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRPM2 Mediates Neutrophil Killing of Disseminated Tumor Cells

(2018) Maya Gershkovitz et al.   CANCER RESEARCH

Tumor-Infiltrating NETs Predict Postsurgical Survival in Patients with Pancreatic Ductal Adenocarcinoma

(2018) Wei Jin et al.   ANNALS OF SURGICAL ONCOLOGY

Neutrophil extracellular traps induced by IL-8 promote diffuse large B cell lymphoma progression via the TLR9 signaling

(2018) Man Nie et al.   CLINICAL CANCER RESEARCH

Neutrophils facilitate ovarian cancer premetastatic niche formation in the omentum

(2018) WonJae Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Attracting Attention: Discovery of IL-8/CXCL8 and the Birth of the Chemokine Field

(2018) Bethany B. Moore et al.   JOURNAL OF IMMUNOLOGY

Tumor-Produced Interleukin-8 Attracts Human Myeloid-Derived Suppressor Cells and Elicits Extrusion of Neutrophil Extracellular Traps (NETs)

(2016) C. Alfaro et al.   CLINICAL CANCER RESEARCH

Quantitative Assessment of the Heterogeneity of PD-L1 Expression in Non–Small-Cell Lung Cancer

(2016) Joseph McLaughlin et al.   JAMA Oncology

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

(2015) Huw D Lewis et al.   Nature Chemical Biology

Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens

(2014) Nora Branzk et al.   NATURE IMMUNOLOGY

Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines

(2014) Christine Schauer et al.   NATURE MEDICINE

Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis

(2013) Jonathan Cools-Lartigue et al.   JOURNAL OF CLINICAL INVESTIGATION

Extracellular DNA traps promote thrombosis

(2010) T. A. Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Netting neutrophils in autoimmune small-vessel vasculitis

(2009) Kai Kessenbrock et al.   NATURE MEDICINE