Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 86, Issue 13, Pages 8997-9006Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.1c00949
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Funding
- Zhejiang Provincial Natural Science Foundation of China [LY20H300001]
- Agricultural and Social Development Fundation of Hangzhou Science and Technology Committee [20201203B148]
- Medical Health Science and Technology Project of Zhejiang Provincial Health Commission [2020KY681, 2020KY679, 2019RC085]
- Scientific Research Foundation of Zhejiang University City College [J-20011, J-20010]
- Hangzhou Municipal University
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A novel divergent domino annulation reactions of sulfur ylides with aryldiazonium tetrafluoroborates have been developed, producing various tetra- and trisubstituted pyrazole derivatives in moderate to good yields. In these one-pot reactions, three molecules of sulfur ylides were used as C-1 synthon to construct complex products with five new chemical bonds formed.
Novel divergent domino annulation reactions of sulfur ylides with aryldiazonium tetrafluoroborates have been developed, affording various tetra- and trisubstituted pyrazole derivatives in moderate to good yields. Three molecules of sulfur ylides were applied as C-1 synthon to construct the complex products with five new chemical bonds formed in these one-pot reactions.
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