4.7 Article

Tunable Electrosynthesis of Anthranilic Acid Derivatives via a C-C Bond Cleavage of Isatins

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 86, Issue 22, Pages 16008-16015

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.1c01017

Keywords

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Funding

  1. National Natural Science Foundation of China [21772185]
  2. Talent Project of Fuyang Normal University [2019kyqd0017]
  3. College Students Innovative Entrepreneurial Training Plan Program [S202010371040]

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An electrocatalytic C-C bond cleavage/functionalization reaction of isatins was developed, leading to the synthesis of a variety of aminobenzoates and aminobenzamides in moderate to good yields under mild conditions.
A facile and direct electrocatalytic C-C bond cleavage/functionalization reaction of isatins was developed. With isatins as the amino-attached C1 sources, a variety of aminobenzoates, and aminobenzamides were synthesized in moderate to good yields under mild conditions.

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