Cotranslational Targeting and Posttranslational Translocation can Cooperate in Spc3 Topogenesis

Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62

(2021) Samuel Itskanov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Membrane Protein Integration and Topogenesis at the ER

(2019) Martin Spiess et al.   PROTEIN JOURNAL

Proper insertion and topogenesis of membrane proteins in the ER depend on Sec63

(2019) Sung-jun Jung et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Defining the physiological role of SRP in protein-targeting efficiency and specificity

(2018) Elizabeth A. Costa et al.   SCIENCE

Profiling of signal sequence characteristics and requirement of different translocation components

(2018) Chewon Yim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Structure of the post-translational protein translocation machinery of the ER membrane

(2018) Xudong Wu et al.   NATURE

Structure of the posttranslational Sec protein-translocation channel complex from yeast

(2018) Samuel Itskanov et al.   SCIENCE

Two alternative binding mechanisms connect the protein translocation Sec71-Sec72 complex with heat shock proteins

(2017) Arati Tripathi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cotranslational signal-independent SRP preloading during membrane targeting

(2016) Justin W. Chartron et al.   NATURE

Crystal structure of a substrate-engaged SecY protein-translocation channel

(2016) Long Li et al.   NATURE

Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling

(2014) C. H. Jan et al.   SCIENCE

A Network of Cytosolic Factors Targets SRP-Independent Proteins to the Endoplasmic Reticulum

(2013) Tslil Ast et al.   CELL

Sec62 Protein Mediates Membrane Insertion and Orientation of Moderately Hydrophobic Signal Anchor Proteins in the Endoplasmic Reticulum (ER)

(2013) Johannes H. Reithinger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Orientation of Internal Signal-Anchor Sequences at the Sec61 Translocon

(2012) Lucyna Kocik et al.   JOURNAL OF MOLECULAR BIOLOGY

Stepwise Insertion and Inversion of a Type II Signal Anchor Sequence in the Ribosome-Sec61 Translocon Complex

(2011) Prasanna K. Devaraneni et al.   CELL

Structural Studies and the Assembly of the Heptameric Post-translational Translocon Complex

(2010) Yoichiro Harada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY