Article
Chemistry, Analytical
Mohamed Sharafeldin, Jason J. Davis
Summary: The development of diagnostic devices relies on the immobilization of biomolecules to generate quantifiable signals. The selectivity and sensitivity of biosensors depend on the interfacial properties, which can be analyzed using characterization techniques.
ANALYTICA CHIMICA ACTA
(2022)
Review
Chemistry, Analytical
Jagadeeswara Rao Bommi, Shekher Kummari, Kavitha Lakavath, Reshmi A. Sukumaran, Lakshmi R. Panicker, Jean Louis Marty, Kotagiri Yugender Goud
Summary: Cancer is a significant global public health issue, accounting for the second highest number of deaths, especially in low- and middle-income countries. It has a huge economic burden of over a trillion dollars annually. Early detection plays a crucial role in effective treatment and improved survival rates, as a large percentage of cancers are diagnosed at late stages. Biosensors offer promise in the early screening of cancer biomarkers. This review highlights recent findings of novel cancer biomarkers, their advantages over traditional biomarkers, and innovative biosensing and diagnostic methods, aiding in early recognition and treatment monitoring of various human cancers.
Review
Chemistry, Analytical
Andrea Bonini, Angela Gilda Carota, Noemi Poma, Federico Maria Vivaldi, Denise Biagini, Daria Bottai, Alessio Lenzi, Arianna Tavanti, Fabio Di Francesco, Tommaso Lomonaco
Summary: Sepsis, a systemic inflammatory dysfunction associated with infectious diseases, is a significant health issue with increasing incidence globally. Traditional diagnostic techniques for sepsis management present challenges, making biosensing technologies a valuable alternative.
Article
Biochemical Research Methods
Youjun Zeng, Zhaogang Nie, Dongyun Kai, Jiajie Chen, Yonghong Shao, Weifu Kong, Zhengqiang Yuan, Ho-Pui Ho, Fangteng Zhang
Summary: This paper presents a novel WSPRi sensing system with a high anti-interference capability and low cost. By introducing devices such as an acousto-optic tunable filter and a halogen lamp, real-time recording of brine concentration and formation of the coffee ring effect were successfully achieved, and the performance of the biosensor was improved. The high anti-interference capability and accuracy of this system will greatly contribute to the exploration of biomolecule behaviors in biological and biochemistry studies.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Review
Engineering, Biomedical
Martalu D. Pazos, Yubing Hu, Yuval Elani, Kathryn L. Browning, Nan Jiang, Ali K. Yetisen
Summary: Functionalizing tattoo inks into optical biosensors offers a promising alternative for continuous and long-term health monitoring. This approach allows for the control of biomarkers in different fluids, facilitating disease diagnosis, progression evaluation, and complication prevention, especially significant for skin diseases.
ADVANCED HEALTHCARE MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Rajesh Kumar, Dinesh Pratap Singh, Romina Munoz, Mongi Amami, Rajesh Kumar Singh, Shipra Singh, Vinod Kumar
Summary: This review article introduces the potential and research progress of graphene and its derivatives in biomedical applications, and summarizes their effects on human health and the environment.
MATERIALS TODAY CHEMISTRY
(2023)
Review
Biochemistry & Molecular Biology
Elaheh Sadat Hosseini, Soheila Mohammadi, Reza Khodarahmi, Mohamad Hassan Fouani, Omid Tavallaei, Khojaste Rahimi Jaberi, Zahra Shabaninejad, Sajjad Janfaza, Rezvan Yazdian-Robati, Soraya Sajadimajd
Summary: This article reviews the application of electrochemical, optical, and optochemical biosensors based on nanotechnology and material science in the early diagnosis of Parkinson's disease. It summarizes PD biomarkers and compares the characteristics of different biosensors and novel strategies for higher sensitivity and selectivity.
CURRENT MEDICINAL CHEMISTRY
(2022)
Article
Engineering, Electrical & Electronic
Carolina Maria Londero, Martina Delgado-Pinar, Christian Cuadrado-Laborde, Miguel V. V. Andres
Summary: This paper introduces a robust and easy-to-fabricate U-shaped fiber sensor based on singlemode telecom fiber, which is applied to biosensing. The resonant nature of the sensing mechanism allows for a large dynamic range of refractive index (RI) variations without the ambiguity seen in other techniques like interferometry. The performance of the U-shaped fiber sensor was studied for different bending radii, optimizing sensitivity and detection limit at 1550 nm operation wavelength, as well as investigating the effect of temperature on response. The shift of the resonant wavelength was measured as a function of external RI within the range of 1.33-1.37, and the detection limit was determined to be (2.88 ± 0.03) × 10(-5) RIU. Furthermore, the device was successfully tested as a proof of concept biosensor using a system model antigen-antibody (BSA-aBSA).
JOURNAL OF LIGHTWAVE TECHNOLOGY
(2023)
Review
Chemistry, Analytical
Taras Kavetskyy, Mahdieh Alipour, Oleh Smutok, Oksana Mushynska, Arnold Kiv, Dietmar Fink, Fatemeh Farshchi, Elham Ahmadian, Mohammad Hasanzadeh
Summary: Iron magnetic nanoparticles (MNPs) play a critical role in various immunoassay technologies, including different biosensors. The review discusses the type and composition of magnetic particles, detection methods, specificity, sensitivity, as well as advantages and limitations of label-free immunosensing of cancer biomarkers.
MICROCHEMICAL JOURNAL
(2021)
Review
Engineering, Biomedical
Ahmad Usman
Summary: This article discusses the current state, challenges, and efforts made in the realization of low-cost, point-of-care, highly sensitive, and specific nanoparticle-enhanced optical biosensing technologies for prostate cancer detection using the PSA biomarker.
IEEE REVIEWS IN BIOMEDICAL ENGINEERING
(2022)
Article
Biophysics
Yantong Liu, Longfei Chen, Le Yu, Chen Yang, Jiaomeng Zhu, Jian Wang, Jingjing Zheng, Fang Wang, Guoqing He, Fenghua Jiang, Chengjun Sun, Li Zheng, Yi Yang
Summary: Microalgal sensors are highly sensitive, accessible, and cost-effective, but face challenges due to motion-induced phase changes and concentration-related multiple scattering. This research introduces a new strategy, utilizing microgel traps and a digital imaging algorithm, to overcome these challenges and develop a microalgae analyzer for atrazine detection.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Analytical
Nour Beydoun, Yann Niberon, Laurent Arnaud, Julien Proust, Komla Nomenyo, Shuwen Zeng, Gilles Lerondel, Aurelien Bruyant
Summary: This research demonstrates that applying a thin layer of aluminum oxide to copper films can effectively slow down the oxidation rate. This simple method could provide a new approach for producing alternative and more sustainable biochips.
Article
Chemistry, Multidisciplinary
Yong Geng, Rijeesh Kizhakidathazhath, Jan P. F. Lagerwall
Summary: The omnidirectional Bragg reflection of cholesteric liquid crystals molded into spheres turns them into narrow-band retroreflectors with distinct circular polarization. These cholesteric spherical reflectors (CSRs) can encode information onto surfaces for far-field optical read-out without false positives, and the retroreflection band is tuned to the near-UV or IR spectra to hide the encoding from detection by the human eye, allowing widespread deployment in human-populated environments; They can be permanently embedded in a binder to minimize undesired scattering and reflections.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Engineering, Electrical & Electronic
Maryam Khodami, Zohreh Hirbodvash, Oleksiy Krupin, Wei Ru Wong, Ewa Lisicka-Skrzek, Howard Northfiel, Choloong Hahn, Pierre Berini
Summary: A novel multimodal biosensor combining plasmonic and electrochemical detection has been fabricated, utilizing grating-coupled plasmonic waveguide sensors for wavelength response and cyclic voltammetry measurements using Au and Pt stripes.
JOURNAL OF MICROELECTROMECHANICAL SYSTEMS
(2021)
Article
Engineering, Electrical & Electronic
Hua-Cheng Lin, Yen-Chieh Wang, Jia-Ming Yang, Cheng-Sheng Huang, Shao-Hsuan Kuo, Bor-Ran Li
Summary: A novel gradient grating period guided-mode resonance biosensor was proposed, showing high sensitivity and potential for future point-of-care applications.
IEEE SENSORS JOURNAL
(2021)
