Article
Agriculture, Dairy & Animal Science
Shuqi Xu, Xinhao Mu, Xin Xu, Congying Bi, Jun Ji, Yunchao Kan, Lunguang Yao, Yingzuo Bi, Qingmei Xie
Summary: This study analyzed 23 complete genomes of Chinese strains of duck hepatitis B virus (DHBV) and predicted and analyzed their recombinant events. These data aid in understanding the intergenotypic recombination of HBV and are expected to promote further research on the epidemiology and evolution of DHBV.
Article
Agriculture, Dairy & Animal Science
Jun Ji, Shuqi Xu, Wanyu Li, Xin Xu, Yunchao Kan, Lunguang Yao, Yingzuo Bi, Qingmei Xie
Summary: Due to its similarity to human hepatitis B virus (HBV), duck HBV (DHBV) is widely used as a model for HBV research. This study analyzed 119 serum samples from ducks and geese in China and found two intergenotypic recombination events in DHBV genomes. Additionally, the study identified a mutation site in the preS region that promotes the pathogenicity of DHBV. These findings highlight the importance of continuous investigation and molecular identification of DHBV.
Article
Immunology
Ijeoma Nwagbo, Adelaide Milani, Annalisa Salviato, Gianpiero Zamperin, Lanre Sulaiman, Nanven Maurice, Clement Meseko, Alice Fusaro, Ismaila Shittu
Summary: Infectious bursal disease (IBD) is a worldwide viral poultry disease that has significant economic and food security impacts. This study focuses on the dynamics of infectious bursal disease virus (IBDV) evolution in Nigeria. The results show the presence of conserved markers associated with highly virulent IBDV strains, as well as unique amino acid mutations with unknown biological functions. Reassortant IBDVs were found circulating in Nigeria, which may explain the failure of vaccination in the poultry population.
Article
Veterinary Sciences
Yu-Rong Wei, Wen-Ge Ma, Ping Wang, Wen Wang, Xiao-Hui Su, Xue-Yun Yang, Xiao-Yun Mi, Jian-Yong Wu, Jiong Huang
Summary: This study characterizes the comparative genomic evolution of the LSDV strain from its first outbreak in China, revealing a common ancestor with LSDV strains from China and Vietnam. The findings provide additional genomic data for the tracking and control of LSDV in China and neighboring countries.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Infectious Diseases
Haruki Komatsu, Ayano Inui, Enkhtaivan Odmaa, Yoshinori Ito, Hiroki Hoshino, Shuichiro Umetsu, Tomoyuki Tsunoda, Tomoo Fujisawa
Summary: Hepatitis B virus (HBV) can be detected in nails and hair, and nails may contain hepatitis B surface antigen (HBsAg), hepatitis delta virus (HDV) RNA, and HD antigen.
BMC INFECTIOUS DISEASES
(2022)
Article
Ecology
Ruifeng Fan, Wei Ma, Shilei Liu, Qingyang Huang
Summary: The study sequenced and compared the chloroplast genomes of several ferns, identifying highly variable loci and confirming the typical quadripartite structures of chloroplast genomes in ferns. The results also showed the relationships among these ferns in terms of their phylogenetic classification.
ECOLOGY AND EVOLUTION
(2021)
Article
Plant Sciences
Zhengying Cao, Linyi Yang, Yaxuan Xin, Wenbin Xu, Qishao Li, Haorong Zhang, Yuxiang Tu, Yu Song, Peiyao Xin
Summary: This study conducted comparative genomic and phylogenetic analyses on seven Neocinnamomum taxa, revealing the genetic structure and evolutionary characteristics of these species. The chloroplast genome of Neocinnamomum has a size range of 150,753-150,956 bp and contains 128 annotated genes. The study identified 31 preferred codons and three highly variable regions. The results of this study will serve as a reference for molecular marker development and phylogenetic research in Neocinnamomum.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Microbiology
Orawee Kaewprasert, Sissades Tongsima, Rick Twee-Hee Ong, Kiatichai Faksri
Summary: This study demonstrates the importance of optimizing parameters and using high-quality variants in whole-genome sequence analysis for accurate bacterial phylogeny reconstruction.
ARCHIVES OF MICROBIOLOGY
(2022)
Article
Virology
Tsutomu Nishizawa, Masaharu Takahashi, Bira Tsatsralt-Od, Khurelbaatar Nyamdavaa, Nyamkhuu Dulmaa, Byankhuu Osorjin, Erdene-Ochir Tseren-Ochir, Tumenjargal Sharav, Chimedtseren Bayasgalan, Boldbaatar Sukhbaatar, Shigeo Nagashima, Kazumoto Murata, Hiroaki Okamoto
Summary: HEV strains belonging to genotype 8 (G8) were identified in Bactrian camels in China, showing high prevalence of HEV infection in Mongolian camels. The two HEV strains from Mongolian camels differed from Chinese camel HEV strains, potentially representing a novel subtype within G8.
Article
Medicine, General & Internal
Zhongping Liu, Yafei Zhang, Mengyuan Xu, Xu Li, Zhenhua Zhang
Summary: This study conducted a meta-analysis of 309 datasets from 110 countries to provide a more detailed and accurate description of HBV genotype and subgenotype distribution globally. The findings suggest that the differences in genotype distribution may be related to ethnicity and human migration in different regions.
Article
Agronomy
Xiaoyan Li, Qiuju Han, Mengyao Li, Qing Luo, Shunhua Zhu, Yangxia Zheng, Guofei Tan
Summary: In this study, the mitochondrial genome of watercress was assembled using Illumina and Nanopore sequencing platforms, revealing a circular structure of 384,074 bp with 28 tRNA genes, 3 rRNA genes, and 34 protein-coding genes. The study also identified watercress's codon preference for leucine, isoleucine, and serine, and its close evolutionary relationship with species such as Bupleurum, Apium, Angelica, and Daucus. This research provides a valuable resource for the study of watercress evolution and molecular breeding.
Article
Microbiology
Maryam Gohar, Irshad Ur Rehman, Amin Ullah, Muhammad Ajmal Khan, Humaira Yasmin, Jamshaid Ahmad, Sadia Butt, Ajaz Ahmad
Summary: This study investigated drug resistance mutations in chronic hepatitis B virus (HBV) patients in Pakistan. The findings revealed multiple drug-resistant mutations and provided insights into the genotypes and subtypes of HBV.
Article
Horticulture
Zhengying Cao, Wenzhi Zhao, Yaxuan Xin, Weixiang Shen, Fei Wang, Qishao Li, Yuxiang Tu, Haorong Zhang, Zhanghong Dong, Peiyao Xin
Summary: This study explored the genetic structure and evolutionary characteristics of the chloroplast genome of Pourthiaea using comparative genomics and phylogenetic analysis. The results showed that the chloroplast genomes of Pourthiaea species were conserved with some variation in spacer regions. Phylogenetic analysis revealed a close relationship between Pourthiaea and Stranvaesia genus. The findings provide valuable insights for breeding, genetic evolution, and phylogeny of Pourthiaea.
Article
Plant Sciences
Myeong-Eun Choe, Ji-Young Kim, Rizwana Begum Syed Nabi, Sang-Ik Han, Kwang-Soo Cho
Summary: In this study, complete chloroplast genome sequences of CMS-S and Korean Sorghum cultivars were obtained, and several SNP and InDel markers were identified. Two InDel markers were developed to distinguish cytotypes, and these markers were successfully applied to identify variant cytotypes in Korean Sorghum cultivars. This study provides reliable markers for marker-assisted selection in Sorghum breeding programs.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Microbiology
Ali Mazloum, Antoinette van Schalkwyk, Andrey Shotin, Alexey Igolkin, Ivan Shevchenko, Konstantin N. Gruzdev, Natalia Vlasova
Summary: This study conducted full genome phylogenetic analysis on ASFV isolates from wild boars in Russia, revealing their genetic relationship and geographical distribution. Three single locus targets were identified as potential molecular markers with high resolving power for future ASFV phylogenetic practices.
Editorial Material
Pediatrics
Mariko Tamiya, Haruki Komatsu, Masaaki Hirabayashi, Motoki Imura, Hiroki Hoshino
PEDIATRICS INTERNATIONAL
(2019)
Article
Infectious Diseases
Haruki Komatsu, Ayano Inui, Yasuto Suzuki, Masaya Sugiyama, Tomoo Fujisawa
BMC INFECTIOUS DISEASES
(2019)
Review
Gastroenterology & Hepatology
Haruki Komatsu, Paul Klenerman, Robert Thimme
HEPATOLOGY RESEARCH
(2020)
Letter
Pediatrics
Haruki Komatsu, Kazutomo Tamaki, Masaaki Hirabayashi
PEDIATRICS AND NEONATOLOGY
(2020)
Review
Pharmacology & Pharmacy
Haruki Komatsu, Ayano Inui, Sachiyo Yoshio, Tomoo Fujisawa
Summary: In order to reduce mortality in children with chronic hepatitis B virus infection, the approvals of nucleos(t)ide analogues (NAs) and pegylated interferon (PEG-IFN) have made antiviral treatment more accessible for children. International guidelines have similar criteria for antiviral treatment of children with chronic HBV, but the WHO guidelines take a cautious approach. Both PEG-IFN and NAs with a high barrier to drug resistance should be considered as first-line treatments for children.
EXPERT OPINION ON PHARMACOTHERAPY
(2021)
Article
Infectious Diseases
Haruki Komatsu, Ayano Inui, Enkhtaivan Odmaa, Yoshinori Ito, Hiroki Hoshino, Shuichiro Umetsu, Tomoyuki Tsunoda, Tomoo Fujisawa
Summary: Hepatitis B virus (HBV) can be detected in nails and hair, and nails may contain hepatitis B surface antigen (HBsAg), hepatitis delta virus (HDV) RNA, and HD antigen.
BMC INFECTIOUS DISEASES
(2022)
Article
Psychiatry
Haruki Komatsu, Karin Hayashi, Fukiko Higashiyama
EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY
(2018)
Article
Infectious Diseases
Hitoshi Yonezawa, Shingo Tanaka, Makito Tanaka, Ryo Kobayashi, Satoshi Takahashi
Summary: The aim of this study was to identify the risk factors for false positives in high-sensitivity HBsAg quantitative tests and reduce the need for neutralization tests. The results showed that younger age, female sex, lower HBsAg values, and reagent improvement were independent risk factors for false positives. The false-positive rate was highest in the range of 0.005-0.049 IU/mL.
JOURNAL OF INFECTION AND CHEMOTHERAPY
(2024)
Article
Infectious Diseases
Nobuaki Kobayashi, Katsushi Tanaka, Suguru Muraoka, Kohei Somekawa, Ayami Kaneko, Sousuke Kubo, Hiromi Matsumoto, Hiroaki Fujii, Keisuke Watanabe, Nobuyuki Horita, Yu Hara, Takeshi Kaneko
Summary: This study identified age, a negative T-SPOT.TB result, elevated CRP levels, and a high NLR as significant independent risk factors for death in hospitalized TB patients. These findings underscore the importance of these parameters in the risk stratification and management of hospitalized TB patients.
JOURNAL OF INFECTION AND CHEMOTHERAPY
(2024)
Article
Infectious Diseases
Naokuni Hishiya, Kenji Uno, Akiyo Nakano, Mitsuru Konishi, Seiya Higashi, Shuhei Eguchi, Tadashi Ariyoshi, Asami Matsumoto, Kentaro Oka, Motomichi Takahashi, Yuki Suzuki, Saori Horiuchi, Nobuyasu Hirai, Yoshihiko Ogawa, Taku Ogawa, Ryuichi Nakano, Keiichi Mikasa, Kei Kasahara, Hisakazu Yano
Summary: This study revealed intestinal dysbiosis near a CD4 count of 350 in HIV-infected patients undergoing cART. These findings contribute to the understanding of intestinal damage and systemic inflammation in HIV infection.
JOURNAL OF INFECTION AND CHEMOTHERAPY
(2024)