Following Transplantation for Acute Myelogenous Leukemia, Donor KIR Cen B02 Better Protects against Relapse than KIR Cen B01

External Validation of Models for KIR2DS1/KIR3DL1-informed Selection of Hematopoietic Cell Donors fails

(2020) Johannes Schetelig et al.   BLOOD

Presence of donor-encoded centromeric KIR B content increases the risk of infectious mortality in recipients of myeloablative, T-cell deplete, HLA-matched HCT to treat AML

(2020) Will P. Bultitude et al.   BONE MARROW TRANSPLANTATION

A Detailed View of KIR Haplotype Structures and Gene Families as Provided by a New Motif-Based Multiple Sequence Alignment

(2020) David Roe et al.   Frontiers in Immunology

Centromeric KIR AA Individuals Harbor Particular KIR Alleles Conferring Beneficial NK Cell Features with Implications in Haplo-Identical Hematopoietic Stem Cell Transplantation

(2020) Léa Dubreuil et al.   Cancers

Diversity of Killer Cell Ig-Like Receptor, HLA Class I, and Their Interactions in Seven Populations of Sub-Saharan Africans

(2019) Neda Nemat-Gorgani et al.   JOURNAL OF IMMUNOLOGY

Novel Approach to Cell Surface Discrimination Between KIR2DL1 Subtypes and KIR2DS1 Identifies Hierarchies in NK Repertoire, Education, and Tolerance

(2019) Jean-Benoît Le Luduec et al.   Frontiers in Immunology

IPD-IMGT/HLA Database

(2019) James Robinson et al.   NUCLEIC ACIDS RESEARCH

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools

(2019) Faviel F Gonzalez-Galarza et al.   NUCLEIC ACIDS RESEARCH

Natural killer cell cytotoxicity and its regulation by inhibitory receptors

(2018) Santosh Kumar   IMMUNOLOGY

Different Selected Mechanisms Attenuated the Inhibitory Interaction of KIR2DL1 with C2+HLA-C in Two Indigenous Human Populations in Southern Africa

(2018) Neda Nemat-Gorgani et al.   JOURNAL OF IMMUNOLOGY

KIR Donor Selection: Feasibility in Identifying better Donors

(2018) Daniel Weisdorf et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

High-Resolution Genetic and Phenotypic Analysis of KIR2DL1 Alleles and Their Association with Pre-Eclampsia

(2018) Oisín Huhn et al.   JOURNAL OF IMMUNOLOGY

Revealing complete complex KIR haplotypes phased by long-read sequencing technology

(2017) D Roe et al.   GENES AND IMMUNITY

KIR3DL1/HLA-B Subtypes Govern Acute Myelogenous Leukemia Relapse After Hematopoietic Cell Transplantation

(2017) Jeanette E. Boudreau et al.   JOURNAL OF CLINICAL ONCOLOGY

Defining KIR and HLA Class I Genotypes at Highest Resolution via High-Throughput Sequencing

(2016) Paul J. Norman et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition

(2016) Philippa M. Saunders et al.   JOURNAL OF EXPERIMENTAL MEDICINE

KIR and HLA under pressure: evidences of coevolution across worldwide populations

(2015) Danillo G. Augusto et al.   HUMAN GENETICS

Polymorphic HLA-C Receptors Balance the Functional Characteristics ofKIRHaplotypes

(2015) Hugo G. Hilton et al.   JOURNAL OF IMMUNOLOGY

Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population

(2015) Hugo G. Hilton et al.   PLoS Genetics

Donor Killer Cell Ig-like Receptor B Haplotypes, Recipient HLA-C1, and HLA-C Mismatch Enhance the Clinical Benefit of Unrelated Transplantation for Acute Myelogenous Leukemia

(2014) S. Cooley et al.   JOURNAL OF IMMUNOLOGY

Co-evolution of Human Leukocyte Antigen (HLA) Class I Ligands with Killer-Cell Immunoglobulin-Like Receptors (KIR) in a Genetically Diverse Population of Sub-Saharan Africans

(2013) Paul J. Norman et al.   PLoS Genetics

Copy number variation leads to considerable diversity for B but not A haplotypes of the human KIR genes encoding NK cell receptors

(2012) W. Jiang et al.   GENOME RESEARCH

Mutation at Positively Selected Positions in the Binding Site for HLA-C Shows That KIR2DL1 Is a More Refined but Less Adaptable NK Cell Receptor Than KIR2DL3

(2012) H. G. Hilton et al.   JOURNAL OF IMMUNOLOGY

Use of NK cell activity in cure by transplant

(2011) Wing Leung   BRITISH JOURNAL OF HAEMATOLOGY

Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia

(2010) S. Cooley et al.   BLOOD

Humans Differ from Other Hominids in Lacking an Activating NK Cell Receptor That Recognizes the C1 Epitope of MHC Class I

(2010) A. K. Moesta et al.   JOURNAL OF IMMUNOLOGY

Different Patterns of Evolution in the Centromeric and Telomeric Regions of Group A and B Haplotypes of the Human Killer Cell Ig-Like Receptor Locus

(2010) Chul-Woo Pyo et al.   PLoS One

Significant functional heterogeneity among KIR2DL1 alleles and a pivotal role of arginine245

(2009) R. Bari et al.   BLOOD

Meiotic recombination generates rich diversity in NK cell receptor genes, alleles, and haplotypes

(2009) P. J. Norman et al.   GENOME RESEARCH

Mechanisms of copy number variation and hybrid gene formation in the KIR immune gene complex

(2009) James A. Traherne et al.   HUMAN MOLECULAR GENETICS

KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A*11 while diminishing avidity for HLA-C

(2009) Thorsten Graef et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The reactivity of Bw4+ HLA-B and HLA-A alleles with KIR3DL1: implications for patient and donor suitability for haploidentical stem cell transplantations

(2008) B. A. Foley et al.   BLOOD

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia

(2008) S. Cooley et al.   BLOOD