Triclosan regulates alternative splicing events of nerve-related genes through RNA-binding protein CELF2 to induce zebrafish neurotoxicity

Triclosan induces zebrafish neurotoxicity by abnormal expression of miR-219 targeting oligodendrocyte differentiation of central nervous system

(2020) Yuhang Ling et al.   ARCHIVES OF TOXICOLOGY

A multi-biomarker approach using integrated biomarker response to assess the effect of pH on triclosan toxicity in Pangasianodon hypophthalmus (Sauvage, 1878)

(2020) Tapas Paul et al.   ENVIRONMENTAL POLLUTION

Differential mechanisms regarding triclosan vs. bisphenol A and fluorene-9-bisphenol induced zebrafish lipid-metabolism disorders by RNA-Seq

(2020) Limei Sun et al.   CHEMOSPHERE

RNA Binding Motif 5 (RBM5) in the CNS—Moving Beyond Cancer to Harness RNA Splicing to Mitigate the Consequences of Brain Injury

(2020) Travis C. Jackson et al.   Frontiers in Molecular Neuroscience

Comparison of Ordinary Cannulated Compression Screw and Double-Head Cannulated Compression Screw Fixation in Vertical Femoral Neck Fractures

(2020) Yuelei Zhang et al.   Biomed Research International

Influence of fixation method and duration of archiving on immunohistochemical staining intensity in embryonic and fetal tissues

(2019) Z. Tauber et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

(2019) Yingyao Zhou et al.   Nature Communications

Neuronal Myocyte-Specific Enhancer Factor 2D (MEF2D) Is Required for Normal Circadian and Sleep Behavior in Mice

(2019) Jennifer A. Mohawk et al.   JOURNAL OF NEUROSCIENCE

Triclosan induces PC12 cells injury is accompanied by inhibition of AKT/mTOR and activation of p38 pathway

(2019) Shao-Jun Li et al.   NEUROTOXICOLOGY

Classification of glioma based on prognostic alternative splicing

(2019) Yaomin Li et al.   BMC Medical Genomics

Fish behavior: A promising model for aquatic toxicology research

(2019) Xiangsheng Hong et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Triclosan alters adult zebrafish behavior and targets acetylcholinesterase activity and expression

(2019) Narasimha Pullaguri et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Regulation of Neuronal Differentiation, Function, and Plasticity by Alternative Splicing

(2018) Elisabetta Furlanis et al.   Annual Review of Cell and Developmental Biology

Response mechanisms to joint exposure of triclosan and its chlorinated derivatives on zebrafish ( Danio rerio ) behavior

(2018) Jinfeng Liu et al.   CHEMOSPHERE

Combined toxicity of triclosan, 2,4-dichlorophenol and 2,4,6-trichlorophenol to zebrafish ( Danio rerio )

(2018) Yuhuan Zhang et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Triclosan-Evoked Neurotoxicity Involves NMDAR Subunits with the Specific Role of GluN2A in Caspase-3-Dependent Apoptosis

(2018) Konrad A. Szychowski et al.   MOLECULAR NEUROBIOLOGY

The 3’UTRs of Myelin Basic Protein mRNAs Regulate Transport, Local Translation and Sensitivity to Neuronal Activity in Zebrafish

(2018) Julie Torvund-Jensen et al.   Frontiers in Molecular Neuroscience

Head skeleton malformations in zebrafish (Danio rerio) to assess adverse effects of mixtures of compounds

(2018) Yvonne C. M. Staal et al.   ARCHIVES OF TOXICOLOGY

Workshop Report: Zebrafish and Other Fish Models—Description of Extrinsic Environmental Factors for Rigorous Experiments and Reproducible Results

(2018) Zoltan M. Varga et al.   Zebrafish

Acute water quality criteria for polycyclic aromatic hydrocarbons, pesticides, plastic additives, and 4-Nonylphenol in seawater

(2017) I. Durán et al.   ENVIRONMENTAL POLLUTION

Zebrafish as an Alternative Vertebrate Model for Investigating Developmental Toxicity—The Triadimefon Example

(2017) Maria Zoupa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Is Triclosan a neurotoxic agent?

(2017) Joanna A Ruszkiewicz et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Distribution of Non-Persistent Endocrine Disruptors in Two Different Regions of the Human Brain

(2017) Thomas P. van der Meer et al.   International Journal of Environmental Research and Public Health

Effects of Triclosan on Neural Stem Cell Viability and Survival

(2016) Bo Kyung Park et al.   Biomolecules & Therapeutics

Consumer products as sources of chemical exposures to children

(2016) Gary L. Ginsberg et al.   CURRENT OPINION IN PEDIATRICS

Mechanisms and Regulation of Alternative Pre-mRNA Splicing

(2015) Yeon Lee et al.   Annual Review of Biochemistry

Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation

(2015) Nicole M. Martinez et al.   GENES & DEVELOPMENT

Alternative Splicing in the Mammalian Nervous System: Recent Insights into Mechanisms and Functional Roles

(2015) Bushra Raj et al.   NEURON

Triclosan induces Fas receptor-dependent apoptosis in mouse neocortical neurons in vitro

(2015) K.A. Szychowski et al.   NEUROSCIENCE

Induced transcription and stability of CELF2 mRNA drives widespread alternative splicing during T-cell signaling

(2015) Michael J. Mallory et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

A census of human RNA-binding proteins

(2014) Stefanie Gerstberger et al.   NATURE REVIEWS GENETICS

rMATS: Robust and flexible detection of differential alternative splicing from replicate RNA-Seq data

(2014) Shihao Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential behavioral responses of zebrafish larvae to yohimbine treatment

(2014) Qiang Li et al.   PSYCHOPHARMACOLOGY

Diversity and conservation of CELF1 and CELF2 RNA and protein expression patterns during embryonic development

(2013) Y. Blech-Hermoni et al.   DEVELOPMENTAL DYNAMICS

Regulation of gene expression in mammalian nervous system through alternative pre-mRNA splicing coupled with RNA quality control mechanisms

(2013) Karen Yap et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Systematic Screening of Behavioral Responses in Two Zebrafish Strains

(2013) Caroline Vignet et al.   Zebrafish

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

CUG-BP, Elav-like family (CELF)-mediated alternative splicing regulation in the brain during health and disease

(2012) Andrea N. Ladd   MOLECULAR AND CELLULAR NEUROSCIENCE

The classification of motor neuron defects in the zebrafish embryo toxicity test (ZFET) as an animal alternative approach to assess developmental neurotoxicity

(2012) Elke Muth-Köhne et al.   NEUROTOXICOLOGY AND TERATOLOGY

Behavioral profiling of zebrafish embryos exposed to a panel of 60 water-soluble compounds

(2011) Shaukat Ali et al.   BEHAVIOURAL BRAIN RESEARCH

The importance of CELF control: molecular and biological roles of the CUG-BP, Elav-like family of RNA-binding proteins

(2011) Twishasri Dasgupta et al.   Wiley Interdisciplinary Reviews-RNA

MicroRNAs coordinate an alternative splicing network during mouse postnatal heart development

(2010) A. Kalsotra et al.   GENES & DEVELOPMENT

Acute and chronic alcohol dose: population differences in behavior and neurochemistry of zebrafish

(2009) R. Gerlai et al.   GENES BRAIN AND BEHAVIOR

The CUGBP2 Splicing Factor Regulates an Ensemble of Branchpoints from Perimeter Binding Sites with Implications for Autoregulation

(2009) Jill A. Dembowski et al.   PLoS Genetics

Characterization of housekeeping genes in zebrafish: male-female differences and effects of tissue type, developmental stage and chemical treatment

(2008) Amy T McCurley et al.   BMC MOLECULAR BIOLOGY