Translation of pulmonary protein therapy from bench to bedside: Addressing the bioavailability challenges
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Translation of pulmonary protein therapy from bench to bedside: Addressing the bioavailability challenges
Authors
Keywords
Therapeutic proteins, Pulmonary delivery, Porous microparticles, Bioavailability, Permeation enhancers, Peptide penetrating cells, Liposomes
Journal
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
Volume 64, Issue -, Pages 102664
Publisher
Elsevier BV
Online
2021-06-17
DOI
10.1016/j.jddst.2021.102664
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Strategies to Enhance Drug Absorption via Nasal and Pulmonary Routes
- (2019) Maliheh Ghadiri et al. Pharmaceutics
- Pulmonary delivery of Nanocomposite Microparticles (NCMPs) incorporating miR-146a for treatment of COPD
- (2019) Adel Mohamed et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Dual-ligand modified liposomes provide effective local targeted delivery of lung-cancer drug by antibody and tumor lineage-homing cell-penetrating peptide
- (2018) Congcong Lin et al. DRUG DELIVERY
- Carriers for the Targeted Delivery of Aerosolized Macromolecules for Pulmonary Pathologies
- (2018) Nashwa Osman et al. Expert Opinion on Drug Delivery
- The use of fatty acids as absorption enhancer for pulmonary drug delivery
- (2018) Maliheh Ghadiri et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Role of Lipid Coating in the Transport of Nanodroplets across the Pulmonary Surfactant Layer Revealed by Molecular Dynamics Simulations
- (2018) Yan Xu et al. LANGMUIR
- Bile salt enhancers for inhalation: Correlation between in vitro and in vivo lung effects
- (2018) Jorid B. Sørli et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Inhalable siRNA-loaded nano-embedded microparticles engineered using microfluidics and spray drying
- (2017) Monica Agnoletti et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Nose-to-Brain Delivery of Peptide Drugs Enhanced by Coadministration of Cell-penetrating Peptides: Therapeutic Potential for Dementia
- (2017) Noriyasu Kamei YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN
- Inhaled gene delivery: a formulation and delivery approach
- (2016) Larissa Gomes dos Reis et al. Expert Opinion on Drug Delivery
- Biokinetic studies of non-complexed siRNA versus nano-sized PEI F25-LMW/siRNA polyplexes following intratracheal instillation into mice
- (2016) Jens Lipka et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Effect of polyunsaturated fatty acids (PUFAs) on airway epithelial cells' tight junction
- (2016) Maliheh Ghadiri et al. PULMONARY PHARMACOLOGY & THERAPEUTICS
- Effect of protease inhibitors on pulmonary bioavailability of therapeutic proteins and peptides in the rat
- (2015) Kiran Prakash Amancha et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Epsilon-poly-l-lysine guided improving pulmonary delivery of supramolecular self-assembled insulin nanospheres
- (2015) Kai Shi et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Improvement of pulmonary absorption of poorly absorbable macromolecules by hydroxypropyl-β-cyclodextrin grafted polyethylenimine (HP-β-CD-PEI) in rats
- (2015) Hailong Zhang et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Pulmonary dry powder vaccine of pneumococcal antigen loaded nanoparticles
- (2015) Nitesh K. Kunda et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Bio-inspired materials in drug delivery: Exploring the role of pulmonary surfactant in siRNA inhalation therapy
- (2015) Lynn De Backer et al. JOURNAL OF CONTROLLED RELEASE
- Absorption-Enhancing Effects of Bile Salts
- (2015) Eskandar Moghimipour et al. MOLECULES
- Polymeric nanoparticles for pulmonary protein and DNA delivery
- (2014) Jyothi U. Menon et al. Acta Biomaterialia
- Phospholipids in pulmonary drug delivery
- (2014) Nathalie Wauthoz et al. EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY
- Mechanism of Mucosal Permeability Enhancement of CriticalSorb® (Solutol® HS15) Investigated In Vitro in Cell Cultures
- (2014) Saif Shubber et al. PHARMACEUTICAL RESEARCH
- A new adjuvanted nanoparticle-based H1N1 influenza vaccine induced antigen-specific local mucosal and systemic immune responses after administration into the lung
- (2014) Vanessa Neuhaus et al. VACCINE
- Application of bile acids in drug formulation and delivery
- (2014) Maja Stojančević et al. Frontiers in Life Science
- Physicochemical Properties of Nanoparticles Regulate Translocation across Pulmonary Surfactant Monolayer and Formation of Lipoprotein Corona
- (2013) Guoqing Hu et al. ACS Nano
- The effect of polymer coatings on physicochemical properties of spray-dried liposomes for nasal delivery of BSA
- (2013) K.H. Chen et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- N-alkylation of highly quaternized chitosan derivatives affects the paracellular permeation enhancement in bronchial epithelia in vitro
- (2013) Berglind Eva Benediktsdóttir et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- MAP0004: dihydroergotamine mesylate inhalation aerosol for acute treatment of migraine
- (2012) Stephen Silberstein EXPERT OPINION ON PHARMACOTHERAPY
- Sodium Caprate Transiently Opens Claudin-5-Containing Barriers at Tight Junctions of Epithelial and Endothelial Cells
- (2012) G. Del Vecchio et al. MOLECULAR PHARMACEUTICS
- Pulmonary delivery of elcatonin using surface-modified liposomes to improve systemic absorption: Polyvinyl alcohol with a hydrophobic anchor and chitosan oligosaccharide as effective surface modifiers
- (2011) Mitsutaka Murata et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Reverse Transcription Polymerase Chain Reaction (RT-PCR) Analysis of Proteolytic Enzymes in Cultures of Human Respiratory Epithelial Cells
- (2011) Leonie Baginski et al. Journal of Aerosol Medicine and Pulmonary Drug Delivery
- A claudin-4 modulator enhances the mucosal absorption of a biologically active peptide
- (2010) Hiroshi Uchida et al. BIOCHEMICAL PHARMACOLOGY
- Noninvasive delivery systems for peptides and proteins in osteoporosis therapy: a retroperspective
- (2010) Herbert Hoyer et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Nanocarriers for pulmonary administration of peptides and therapeutic proteins
- (2010) Fernanda Andrade et al. Nanomedicine
- Enhancement of Insulin Absorption through Mucosal Membranes Using Cationic Polymers
- (2010) Toshinobu SEKI YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN
- Nanoparticles in cellular drug delivery
- (2009) Amir H. Faraji et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Insulin-micro- and nanoparticles for pulmonary delivery
- (2009) Claudia Klingler et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Insulin nanoparticles: Stability and aerosolization from pressurized metered dose inhalers
- (2009) Bildad K. Nyambura et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Aerosolized liposomes with dipalmitoyl phosphatidylcholine enhance pulmonary insulin delivery
- (2009) Sumio Chono et al. JOURNAL OF CONTROLLED RELEASE
- Simultaneously manufactured nano-in-micro (SIMANIM) particles for dry-powder modified-release delivery of antibodies
- (2009) Richard S. Kaye et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Aquasomes: a promising carrier for peptides and protein delivery
- (2009) Marakanam S. Umashankar et al. Nanomedicine-Nanotechnology Biology and Medicine
- Shape-Controlled Synthesis of Metal Nanocrystals: Simple Chemistry Meets Complex Physics?
- (2008) Younan Xia et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Targeted Drug-Aerosol Delivery in the Human Respiratory System
- (2008) C. Kleinstreuer et al. Annual Review of Biomedical Engineering
- Potential use of tight junction modulators to reversibly open membranous barriers and improve drug delivery
- (2008) Mária A. Deli BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Structure–activity relationship studies of permeability modulating peptide AT-1002
- (2008) Min Li et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Preparation and properties of inhalable nanocomposite particles: Effects of the size, weight ratio of the primary nanoparticles in nanocomposite particles and temperature at a spray-dryer inlet upon properties of nanocomposite particles
- (2008) Keishiro Tomoda et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Permeation Studies and Histological Examination of Sheep Nasal Mucosa Following Administration of Different Nasal Formulations with or without Absorption Enhancers
- (2008) Ercüment Karasulu et al. DRUG DELIVERY
- Microspheres containing lipid/chitosan nanoparticles complexes for pulmonary delivery of therapeutic proteins
- (2008) Ana Grenha et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Noncytotoxic Clostridium perfringens Enterotoxin (CPE) Variants Localize CPE Intestinal Binding and Demonstrate a Relationship between CPE-Induced Cytotoxicity and Enterotoxicity
- (2008) J. G. Smedley et al. INFECTION AND IMMUNITY
- Dry powder inhalers (DPIs)—A review of device reliability and innovation
- (2008) Nazrul Islam et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Solid lipid nanoparticles for pulmonary delivery of insulin
- (2008) Jie Liu et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Inhaled nanoparticles—A current review
- (2008) Wei Yang et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Mechanism of action of ZOT-derived peptide AT-1002, a tight junction regulator and absorption enhancer
- (2008) S GOPALAKRISHNAN et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Increased Biological Half-Life of Aerosolized Liposomal Recombinant Human Cu/Zn Superoxide Dismutase in Pigs
- (2008) Martin Kaipel et al. Journal of Aerosol Medicine and Pulmonary Drug Delivery
- Spray-freeze-dried dry powder inhalation of insulin-loaded liposomes for enhanced pulmonary delivery
- (2008) Ru Bi et al. JOURNAL OF DRUG TARGETING
- Nanomedicine: Application of Nanobiotechnology in Medical Practice
- (2008) K.K. Jain MEDICAL PRINCIPLES AND PRACTICE
- Nanoparticle formulations in pulmonary drug delivery
- (2008) Mark M. Bailey et al. MEDICINAL RESEARCH REVIEWS
- Intrapulmonary potential of polyethylene glycol-modified glucagon-like peptide-1s as a type 2 anti-diabetic agent
- (2008) Kang Choon Lee et al. REGULATORY PEPTIDES
- The Role of Macrophages in the Clearance of Inhaled Ultrafine Titanium Dioxide Particles
- (2007) Marianne Geiser et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Preparation and physicochemical characterization of supercritically dried insulin-loaded microparticles for pulmonary delivery
- (2007) Maryam Amidi et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now