Systemic dendrimer nanotherapies for targeted suppression of choroidal inflammation and neovascularization in age-related macular degeneration
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Title
Systemic dendrimer nanotherapies for targeted suppression of choroidal inflammation and neovascularization in age-related macular degeneration
Authors
Keywords
Age-related macular degeneration (AMD), Systemic therapies, PAMAM dendrimers, Microglia/macrophages, Triamcinolone acetonide, Choroidal neovascularization, Retinal inflammation
Journal
JOURNAL OF CONTROLLED RELEASE
Volume 335, Issue -, Pages 527-540
Publisher
Elsevier BV
Online
2021-05-29
DOI
10.1016/j.jconrel.2021.05.035
References
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Note: Only part of the references are listed.- Evolution of oxidative stress, inflammation and neovascularization in the choroid and retina in a subretinal lipid induced age-related macular degeneration model
- (2020) Soo-Young Kim et al. EXPERIMENTAL EYE RESEARCH
- Nanotechnology-Based Strategies for siRNA Brain Delivery for Disease Therapy
- (2018) Meng Zheng et al. TRENDS IN BIOTECHNOLOGY
- Cognitive impairments induced by necrotizing enterocolitis can be prevented by inhibiting microglial activation in mouse brain
- (2018) Diego F. Niño et al. Science Translational Medicine
- Targeted Intraceptor Nanoparticle for Neovascular Macular Degeneration: Preclinical Dose Optimization and Toxicology Assessment
- (2017) Xiaohui Zhang et al. MOLECULAR THERAPY
- Uptake of dendrimer-drug by different cell types in the hippocampus after hypoxic–ischemic insult in neonatal mice: Effects of injury, microglial activation and hypothermia
- (2017) Christina L. Nemeth et al. Nanomedicine-Nanotechnology Biology and Medicine
- Efficacy of aflibercept on exudative age-related macular degeneration in patients exhibiting complete ranibizumab resistance and tachyphylaxis
- (2016) Gokcen Gokce et al. ARQUIVOS BRASILEIROS DE OFTALMOLOGIA
- Nanoscale effects in dendrimer-mediated targeting of neuroinflammation
- (2016) Elizabeth Nance et al. BIOMATERIALS
- Treatment strategies for refractory diabetic macular edema: switching anti-VEGF treatments, adopting corticosteroid-based treatments, and combination therapy
- (2016) Rehan M. Hussain et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- A Review of the Role of Intravitreal Corticosteroids as an Adjuvant to Antibiotics in Infectious Endophthalmitis
- (2016) Dawn Ching Wen Ho et al. OCULAR IMMUNOLOGY AND INFLAMMATION
- “Small Blood Vessels: Big Health Problems?”: Scientific Recommendations of the National Institutes of Health Workshop
- (2016) Francesca Bosetti et al. Journal of the American Heart Association
- Histopathological Insights Into Choroidal Vascular Loss in Clinically Documented Cases of Age-Related Macular Degeneration
- (2016) Johanna M. Seddon et al. JAMA Ophthalmology
- Dendrimers Target the Ischemic Lesion in Rodent and Primate Models of Nonarteritic Anterior Ischemic Optic Neuropathy
- (2016) Yan Guo et al. PLoS One
- Intracellular delivery of dendrimer triamcinolone acetonide conjugates into microglial and human retinal pigment epithelial cells
- (2015) Siva P. Kambhampati et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Systemic dendrimer-drug treatment of ischemia-induced neonatal white matter injury
- (2015) Elizabeth Nance et al. JOURNAL OF CONTROLLED RELEASE
- Intravitreal Triamcinolone Acetonide in the Treatment of Ophthalmic Inflammatory Diseases with Macular Edema: A Meta-Analysis Study
- (2015) Claudio Bucolo et al. JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS
- Diabetic Macular Edema: Pathophysiology and Novel Therapeutic Targets
- (2015) Arup Das et al. OPHTHALMOLOGY
- Retinal microglia: Just bystander or target for therapy?
- (2015) Marcus Karlstetter et al. PROGRESS IN RETINAL AND EYE RESEARCH
- SUBFOVEAL CHOROIDAL THICKNESS CHANGES AFTER INTRAVITREAL RANIBIZUMAB AND PHOTODYNAMIC THERAPY FOR RETINAL ANGIOMATOUS PROLIFERATION
- (2015) Ichiro Maruko et al. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
- GEOGRAPHIC ATROPHY IN PATIENTS RECEIVING ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR FOR NEOVASCULAR AGE-RELATED MACULAR DEGENERATION
- (2015) Luna Xu et al. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
- The effect of triamcinolone acetonide on laser-induced choroidal neovascularization in mice using a hypoxia visualization bio-imaging probe
- (2015) Shinsuke Takata et al. Scientific Reports
- Dendrimer Brain Uptake and Targeted Therapy for Brain Injury in a Large Animal Model of Hypothermic Circulatory Arrest
- (2014) Manoj K. Mishra et al. ACS Nano
- Different effects of intravitreally injected ranibizumab and aflibercept on retinal and choroidal tissues of monkey eyes
- (2014) Sylvie Julien et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Macroglia-Microglia Interactions via TSPO Signaling Regulates Microglial Activation in the Mouse Retina
- (2014) M. Wang et al. JOURNAL OF NEUROSCIENCE
- EXACERBATION OF CHOROIDAL AND RETINAL PIGMENT EPITHELIAL ATROPHY AFTER ANTI–VASCULAR ENDOTHELIAL GROWTH FACTOR TREATMENT IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION
- (2014) Mei Young et al. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
- Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis
- (2014) Wan Ling Wong et al. Lancet Global Health
- Targeted Intraceptor Nanoparticle Therapy Reduces Angiogenesis and Fibrosis in Primate and Murine Macular Degeneration
- (2013) Ling Luo et al. ACS Nano
- Intraocular Concentrations of Cytokines and Chemokines in Rhegmatogenous Retinal Detachment and the Effect of Intravitreal Triamcinolone Acetonide
- (2013) Hiroshi Kunikata et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- Brain and retinal microglia in health and disease: An unrecognized target of the renin-angiotensin system
- (2013) Claudia A McCarthy et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Pharmacokinetics of bevacizumab after topical and intravitreal administration in human eyes
- (2013) Elad Moisseiev et al. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- Alternative treatments to inhibit VEGF in age-related choroidal neovascularisation: 2-year findings of the IVAN randomised controlled trial
- (2013) Usha Chakravarthy et al. LANCET
- Biodistribution of Fluorescently Labeled PAMAM Dendrimers in Neonatal Rabbits: Effect of Neuroinflammation
- (2013) Wojciech G. Lesniak et al. MOLECULAR PHARMACEUTICS
- Bevacizumab and Triamcinolone Acetonide for Choroidal Neovascularization Due to Age-Related Macular Degeneration Unresponsive to Antivascular Endothelial Growth Factors
- (2012) Daniele Veritti et al. JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS
- Animal models of age related macular degeneration
- (2012) Mark E. Pennesi et al. MOLECULAR ASPECTS OF MEDICINE
- Understanding age-related macular degeneration (AMD): Relationships between the photoreceptor/retinal pigment epithelium/Bruch’s membrane/choriocapillaris complex
- (2012) Imran Bhutto et al. MOLECULAR ASPECTS OF MEDICINE
- Ophthalmic drug discovery: novel targets and mechanisms for retinal diseases and glaucoma
- (2012) Kang Zhang et al. NATURE REVIEWS DRUG DISCOVERY
- Neovascular Age-Related Macular Degeneration
- (2012) Daniele Veritti et al. OPHTHALMOLOGICA
- Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networks
- (2012) Aaron M Newman et al. Genome Medicine
- Dendrimer-based targeted intravitreal therapy for sustained attenuation of neuroinflammation in retinal degeneration
- (2011) Raymond Iezzi et al. BIOMATERIALS
- Clinical Evidence of Intravitreal Triamcinolone Acetonide in the Management of Age-Related Macular Degeneration
- (2011) E. M. Becerra et al. CURRENT DRUG TARGETS
- A Rat Model for Choroidal Neovascularization Using Subretinal Lipid Hydroperoxide Injection
- (2010) Takayuki Baba et al. AMERICAN JOURNAL OF PATHOLOGY
- Monocyte Chemoattractant Protein 1, Intercellular Adhesion Molecule 1, and Vascular Cell Adhesion Molecule 1 in Exudative Age-Related Macular Degeneration
- (2010) Jost B. Jonas ARCHIVES OF OPHTHALMOLOGY
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- (2010) Stephen J. Kim ARCHIVES OF OPHTHALMOLOGY
- Triamcinolone Crystal Size
- (2010) Mark E. Kleinman et al. OPHTHALMOLOGY
- The use of intraocular corticosteroids
- (2009) Daniel F Kiernan et al. EXPERT OPINION ON PHARMACOTHERAPY
- Intraocular Sustained-Release Delivery Systems for Triamcinolone Acetonide
- (2009) Saffar Mansoor et al. PHARMACEUTICAL RESEARCH
- Microglia in the Mouse Retina Alter the Structure and Function of Retinal Pigmented Epithelial Cells: A Potential Cellular Interaction Relevant to AMD
- (2009) Wenxin Ma et al. PLoS One
- Comparative Therapy Evaluation of Intravitreal Bevacizumab and Triamcinolone Acetonide on Persistent Diffuse Diabetic Macular Edema
- (2008) Masahiko Shimura et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- Macrophages in neovascular age-related macular degeneration: friends or foes?
- (2008) J M Skeie et al. EYE
- INTRAVITREAL INJECTION OF BEVACIZUMAB COMBINED WITH VERTEPORFIN PHOTODYNAMIC THERAPY FOR CHOROIDAL NEOVASCULARIZATION IN AGE-RELATED MACULAR DEGENERATION
- (2008) BRADLEY T. SMITH et al. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
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