Circulating Bile Acid Profiles: A Need for Further Examination

Bile acids and their receptors in metabolic disorders

(2021) Stefano Fiorucci et al.   PROGRESS IN LIPID RESEARCH

Discovery, optimization, and evaluation of non-bile acid FXR/TGR5 dual agonists

(2021) Sachiho Miyata et al.   Scientific Reports

A novel role for farnesoid X receptor in the bile acid‐mediated intestinal glucose homeostasis

(2020) Long Zhao et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Alternate-day fasting alleviates diabetes-induced glycolipid metabolism disorders: roles of FGF21 and bile acids

(2020) Hongbo Zhang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Analysis of bile acid profile in plasma to differentiate cholangiocarcinoma from benign biliary diseases and healthy controls

(2020) Xiaofen Zhang et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Bile acids profile, histopathological indices and genetic variants for non-alcoholic fatty liver disease progression

(2020) Nisreen Nimer et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Bile acid alterations in nonalcoholic fatty liver disease, obesity, insulin resistance and type 2 diabetes

(2019) Oscar Chávez-Talavera et al.   CURRENT OPINION IN LIPIDOLOGY

Fasting serum bile acids concentration is associated with insulin resistance independently of diabetes status

(2019) Sang-Guk Lee et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Saxagliptin alters bile acid profiles and yields metabolic benefits in drug naïve overweight or obese type 2 diabetes

(2019) Wen Li et al.   Journal of Diabetes

Acute Changes of Bile Acids and FGF19 After Sleeve Gastrectomy and Roux-en-Y Gastric Bypass

(2019) Yutao Chen et al.   OBESITY SURGERY

Designing a new therapy for T2DM

(2019) Claire Greenhill   Nature Reviews Endocrinology

Postprandial dyslipidemia, hyperinsulinemia, and impaired gut peptides/bile acids in adolescents with obesity

(2019) Victoria Higgins et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The integrative biology of type 2 diabetes

(2019) Michael Roden et al.   NATURE

Modulation of endothelium-derived nitric oxide production and activity by taurine and taurine-conjugated bile acids

(2019) Daniele M. Guizoni et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Associations between Dietary Patterns and Bile Acids—Results from a Cross-Sectional Study in Vegans and Omnivores

(2019) Iris Trefflich et al.   Nutrients

Response of fibroblast growth factor 19 and bile acid synthesis after a body weight-adjusted oral fat tolerance test in overweight and obese NAFLD patients: a non-randomized controlled pilot trial

(2018) Dana Friedrich et al.   BMC GASTROENTEROLOGY

The influences of cholecystectomy on the circadian rhythms of bile acids as well as the enterohepatic transporters and enzymes systems in mice

(2018) Fan Zhang et al.   CHRONOBIOLOGY INTERNATIONAL

The Nuclear Bile Acid Receptor FXR is a PKA- and FOXA2-Sensitive Activator of Fasting Hepatic Gluconeogenesis

(2018) Maheul Ploton et al.   JOURNAL OF HEPATOLOGY

Circulating bile acids in healthy adults respond differently to a dietary pattern characterized by whole grains, legumes and fruits and vegetables compared to a diet high in refined grains and added sugars: A randomized, controlled, crossover feeding study

(2018) Bigina N.R. Ginos et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Serum bile acid patterns are associated with the presence of NAFLD in twins, and dose-dependent changes with increase in fibrosis stage in patients with biopsy-proven NAFLD

(2018) Cyrielle Caussy et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Suppressed hepatic bile acid signalling despite elevated production of primary and secondary bile acids in NAFLD

(2017) Na Jiao et al.   GUT

The presence and severity of nonalcoholic steatohepatitis is associated with specific changes in circulating bile acids

(2017) Puneet Puri et al.   HEPATOLOGY

Bile Acid Alterations Are Associated With Insulin Resistance, but Not With NASH, in Obese Subjects

(2017) Vanessa Legry et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Acute caloric restriction counteracts hepatic bile acid and cholesterol deficiency in morbid obesity

(2017) S. Straniero et al.   JOURNAL OF INTERNAL MEDICINE

Analyses of gut microbiota and plasma bile acids enable stratification of patients for antidiabetic treatment

(2017) Yanyun Gu et al.   Nature Communications

Taurine Supplementation Lowers Blood Pressure and Improves Vascular Function in Prehypertension

(2016) Qianqian Sun et al.   HYPERTENSION

Increased Bile Acid Synthesis and Impaired Bile Acid Transport in Human Obesity

(2016) Rebecca A. Haeusler et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Postprandial Plasma Concentrations of Individual Bile Acids and FGF-19 in Patients With Type 2 Diabetes

(2016) David P. Sonne et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Insulin Resistance is Associated With Total Bile Acid Level in Type 2 Diabetic and Nondiabetic Population

(2016) Wanwan Sun et al.   MEDICINE

Elevated First-Trimester Total Bile Acid is Associated with the Risk of Subsequent Gestational Diabetes

(2016) Wolin Hou et al.   Scientific Reports

Unconjugated Bile Acids Influence Expression of Circadian Genes: A Potential Mechanism for Microbe-Host Crosstalk

(2016) Kalaimathi Govindarajan et al.   PLoS One

Effects of Diurnal Variation of Gut Microbes and High-Fat Feeding on Host Circadian Clock Function and Metabolism

(2015) Vanessa Leone et al.   Cell Host & Microbe

Altered Bile Acid Metabolome in Patients with Nonalcoholic Steatohepatitis

(2015) Brian C. Ferslew et al.   DIGESTIVE DISEASES AND SCIENCES

Serum Bile Acid Levels in Children with NAFLD

(2015) Jörg Jahnel et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Chenodeoxycholic acid, an endogenous FXR ligand alters adipokines and reverses insulin resistance

(2015) Mohamed Sham Shihabudeen et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Plasma bile acids show a positive correlation with body mass index and are negatively associated with cognitive restraint of eating in obese patients

(2015) Philip Prinz et al.   Frontiers in Neuroscience

Bile acids, obesity, and the metabolic syndrome

(2014) Huijuan Ma et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Correlation between postprandial bile acids and body fat mass in healthy normal-weight subjects

(2014) Tatsuya Suzuki et al.   CLINICAL BIOCHEMISTRY

Fasting Serum Taurine-Conjugated Bile Acids Are Elevated in Type 2 Diabetes and Do Not Change With Intensification of Insulin

(2014) Marlene Wewalka et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Glucose-lowering effects of intestinal bile acid sequestration through enhancement of splanchnic glucose utilization

(2014) Janne Prawitt et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Human Insulin Resistance Is Associated With Increased Plasma Levels of 12 -Hydroxylated Bile Acids

(2013) R. A. Haeusler et al.   DIABETES

A Role for Fibroblast Growth Factor 19 and Bile Acids in Diabetes Remission After Roux-en-Y Gastric Bypass

(2013) G. S. Gerhard et al.   DIABETES CARE

Roux-en-Y gastric bypass normalizes the blunted postprandial bile acid excursion associated with obesity

(2013) N N Ahmad et al.   INTERNATIONAL JOURNAL OF OBESITY

Discovery of a Highly Potent, Nonabsorbable Apical Sodium-Dependent Bile Acid Transporter Inhibitor (GSK2330672) for Treatment of Type 2 Diabetes

(2013) Yulin Wu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Impact of Parenteral Nutrition Versus Fasting on Hepatic Bile Acid Production and Transport in a Rabbit Model of Prolonged Critical Illness

(2013) Yoo-Mee Vanwijngaerden et al.   SHOCK

Association Between Nonalcoholic Fatty Liver Disease and Risk for Hepatocellular Cancer, Based on Systematic Review

(2012) Donna L. White et al.   Clinical Gastroenterology and Hepatology

Glucocorticoid receptor mediates the gluconeogenic activity of the farnesoid X receptor in the fasting condition

(2012) Barbara Renga et al.   FASEB JOURNAL

Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice

(2012) Bo Kong et al.   HEPATOLOGY

Gallbladder and gastric motility in obese newborns, pre-adolescents and adults

(2012) Agostino Di Ciaula et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Elevated hepatic fatty acid oxidation, high plasma fibroblast growth factor 21, and fasting bile acids in nonalcoholic steatohepatitis

(2011) Srinivasan Dasarathy et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

PXR Prevents Cholesterol Gallstone Disease by Regulating Biosynthesis and Transport of Bile Salts

(2011) Jinhan He et al.   GASTROENTEROLOGY

Bile Acid Is a Host Factor That Regulates the Composition of the Cecal Microbiota in Rats

(2011) K.B.M. Saiful Islam et al.   GASTROENTEROLOGY

Glucose and Insulin Induction of Bile Acid Synthesis

(2011) Tiangang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plasma Bile Acids Are Associated with Energy Expenditure and Thyroid Function in Humans

(2011) Johann Ockenga et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Fasting plasma chenodeoxycholic acid and cholic acid concentrations are inversely correlated with insulin sensitivity in adults

(2011) Bertrand Cariou et al.   Nutrition & Metabolism

Bile Acid Metabolites in Serum: Intraindividual Variation and Associations with Coronary Heart Disease, Metabolic Syndrome and Diabetes Mellitus

(2011) Carine Steiner et al.   PLoS One

The relationship between postprandial bile acid concentration, GLP-1, PYY and ghrelin

(2010) R. E. Roberts et al.   CLINICAL ENDOCRINOLOGY

Two weeks taurine supplementation reverses endothelial dysfunction in young male type 1 diabetics

(2010) Michael A Moloney et al.   Diabetes & Vascular Disease Research

Improved glycemic control with colesevelam treatment in patients with type 2 diabetes is not directly associated with changes in bile acid metabolism

(2010) Gemma Brufau et al.   HEPATOLOGY

Plasma metabolomic profile in nonalcoholic fatty liver disease

(2010) Satish C. Kalhan et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Postprandial plasma bile acid responses in normal weight and obese subjects

(2010) C. Glicksman et al.   ANNALS OF CLINICAL BIOCHEMISTRY

OST alpha-OST beta: a key membrane transporter of bile acids and conjugated steroids

(2009) Nazzareno Ballatori   Frontiers in Bioscience-Landmark

The 2009 Stock Conference Report: Inflammation, Obesity and Metabolic Disease

(2009) A. L. Hevener et al.   Obesity Reviews

Free fatty acids sensitize hepatocytes to bile acid-induced apoptosis

(2008) Thomas Pusl et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity

(2008) Oded Shaham et al.   Molecular Systems Biology