Evaluation of putative CSF biomarkers in paediatric spinal muscular atrophy (SMA) patients before and during treatment with nusinersen

Nusinersen treatment and cerebrospinal fluid neurofilaments: An explorative study on Spinal Muscular Atrophy type 3 patients

(2020) Irene Faravelli et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Neurofilaments and tau in CSF in an infant with SMA type 1 treated with nusinersen

(2019) Benedikt Winter et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Neurofilament as a potential biomarker for spinal muscular atrophy

(2019) Basil T. Darras et al.   Annals of Clinical and Translational Neurology

Serum neurofilament heavy chains as early marker of motor neuron degeneration

(2019) Maxim De Schaepdryver et al.   Annals of Clinical and Translational Neurology

Neurofilament Heavy Chain and Tau Protein Are Not Elevated in Cerebrospinal Fluid of Adult Patients with Spinal Muscular Atrophy during Loading with Nusinersen

(2019) Andreas Totzeck et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neurofilament light chain in serum of adolescent and adult SMA patients under treatment with nusinersen

(2019) Claudia D. Wurster et al.   JOURNAL OF NEUROLOGY

P.270Association between plasma phosphorylated neurofilament heavy chain and efficacy endpoints in the nusinersen NURTURE study

(2019) F. Muntoni et al.   NEUROMUSCULAR DISORDERS

Nusinersen versus Sham Control in Later-Onset Spinal Muscular Atrophy

(2018) Eugenio Mercuri et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evidence in focus: Nusinersen use in spinal muscular atrophy

(2018) David Michelson et al.   NEUROLOGY

Cerebrospinal Fluid Neurogranin as a Biomarker of Neurodegenerative Diseases: A Cross-Sectional Study

(2017) Simone Lista et al.   JOURNAL OF ALZHEIMERS DISEASE

Comparison of elevated phosphorylated neurofilament heavy chains in serum and cerebrospinal fluid of patients with amyotrophic lateral sclerosis

(2017) Maxim De Schaepdryver et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Nusinersen versus Sham Control in Infantile-Onset Spinal Muscular Atrophy

(2017) Richard S. Finkel et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Cerebrospinal Fluid Neurogranin/BACE1 Ratio is a Potential Correlate of Cognitive Decline in Alzheimer’s Disease

(2016) Ann De Vos et al.   JOURNAL OF ALZHEIMERS DISEASE

Glia and alpha-synuclein in neurodegeneration: A complex interaction

(2016) Dominik Brück et al.   NEUROBIOLOGY OF DISEASE

Baseline results of the NeuroNEXT spinal muscular atrophy infant biomarker study

(2016) Stephen J. Kolb et al.   Annals of Clinical and Translational Neurology

Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease

(2015) Hlin Kvartsberg et al.   Alzheimers & Dementia

C-terminal neurogranin is increased in cerebrospinal fluid but unchanged in plasma in Alzheimer's disease

(2015) Ann De Vos et al.   Alzheimers & Dementia

Spectrum of Neuropathophysiology in Spinal Muscular Atrophy Type I

(2015) Brian N. Harding et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Non-Aggregating Tau Phosphorylation by Cyclin-Dependent Kinase 5 Contributes to Motor Neuron Degeneration in Spinal Muscular Atrophy

(2015) Nimrod Miller et al.   JOURNAL OF NEUROSCIENCE

 -Synuclein in CSF of patients with severe traumatic brain injury

(2013) S. Mondello et al.   NEUROLOGY

Cerebrospinal Fluid Brain Injury Biomarkers in Children: A Multicenter Study

(2013) Pashtun Shahim et al.   PEDIATRIC NEUROLOGY

Low CSF Levels of Both α-Synuclein and the α-Synuclein Cleaving Enzyme Neurosin in Patients with Synucleinopathy

(2013) Malin Wennström et al.   PLoS One

Elevated cerebrospinal fluid neurofilament light levels in patients with amyotrophic lateral sclerosis: a possible marker of disease severity and progression

(2012) R. Tortelli et al.   EUROPEAN JOURNAL OF NEUROLOGY

Cerebrospinal fluid biomarkers in neurological diseases in children

(2012) Pashtun Shahim et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model

(2011) Yimin Hua et al.   NATURE

 -Secretase-dependent amyloid-  is increased in Niemann-Pick type C: A cross-sectional study

(2010) N. Mattsson et al.   NEUROLOGY

Neuropeptide changes and neuroactive amino acids in CSF from humans and sheep with neuronal ceroid lipofuscinoses (NCLs, Batten disease)

(2009) Graham W. Kay et al.   NEUROCHEMISTRY INTERNATIONAL

Elevated Cerebrospinal Fluid BACE1 Activity in Incipient Alzheimer Disease

(2008) Henrik Zetterberg et al.   ARCHIVES OF NEUROLOGY