Article
Multidisciplinary Sciences
Xiaofan Yuan, Lei Guo, Jianhong Wang, Duozi Wang, Shu Yang, Fuqiang Guo
Summary: Using serum GFAP and S100B with imaging tools can evaluate cerebral vessel reactivity after CAS, with significant improvement in CVR at 30-day follow-up, more severe stenosis led to more obvious improvement.
SCIENTIFIC REPORTS
(2021)
Article
Neurosciences
Chun Li, Jihong Meng, Baoxin Xu, Xiaodong Li, Miaomiao Li, Xue Du, Shaoyi Li, Weining Ma
Summary: This study aimed to investigate the relationship between CT angiography (CTA) manifestations in the anterior cerebral artery a1 segment (A1) and hemodynamics in patients with internal carotid artery stenosis (ICAS). A total of 97 cases were analyzed, and the degree of ICAS and symmetry of A1 were evaluated using CTA examination, while hemodynamic indexes were measured using transcranial Doppler (TCD). The study found that the presentation of A1 on the side of ICAS reflects the overall changes in intracranial hemodynamics, and a combination of TCD and CTA examination of A1 can help determine the location and degree of ICAS.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Pharmacology & Pharmacy
Z. Yuan, Q. Wei, J. Wang
Summary: This study aimed to describe the alternations in cerebral and ocular blood flow velocities in symptomatic patients with unilateral carotid stenosis after carotid endarterectomy. The results showed significant improvements in blood flow velocities after surgery, but a tendency for reduction in the long-term follow-up.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jeanne Hersant, Pierre Ramondou, Delphine Douillet, Stanislas Abrard, Patrick Vandeputte, Francois-Xavier Lapebie, Pierre Abraham, Samir Henni
Summary: This study investigated the correlation between hemodynamic parameters measured by duplex ultrasonography and dual-gate Doppler mode for quantifying stenosis. Results showed high correlation, but also highlighted discrepancies in measurement precision between the two methods. Overall, the dual-gate Doppler mode may offer advantages over conventional ultrasonography for hemodynamic measurements.
Article
Radiology, Nuclear Medicine & Medical Imaging
Ziguang Yan, Guochen Niu, Weiping Sun, Junmei Li, Min Yang
Summary: This retrospective cohort study aimed to investigate the changes in cerebral hemodynamics in the early stage following carotid artery stenting (CAS). The study found that the ipsilateral middle cerebral artery (MCA) peak systolic velocity (PSV) and pulsatility index (PI) significantly increased at 1 hour and 3 hours following CAS, particularly in patients with severe stenosis.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2023)
Article
Clinical Neurology
Sara Mazzucco, Linxin Li, Iain J. McGurgan, Maria Assuncao Tuna, Nicoletta Brunelli, Lucy E. Binney, Peter M. Rothwell
Summary: The effects of early blood pressure lowering on cerebral perfusion in patients with moderate/severe occlusive carotid disease after transient ischemic attack (TIA) and non-disabling stroke are uncertain. This study aimed to evaluate the changes in transcranial Doppler (TCD) indices in patients undergoing blood pressure lowering soon after TIA/non-disabling stroke. The results showed that blood pressure lowering treatment in patients with moderate/severe occlusive carotid disease is safe in the acute setting of TIA clinics.
INTERNATIONAL JOURNAL OF STROKE
(2022)
Article
Geriatrics & Gerontology
Rita Magyar-Stang, Hanga Pal, Borbala Csanyi, Anna Gaal, Zsuzsanna Mihaly, Zsofia Czinege, Tamas Csipo, Zoltan Ungvari, Peter Sotonyi, Andrea Varga, Tamas Horvath, Daniel Bereczki, Akos Koller, Robert Debreczeni
Summary: Unhealthy vascular aging promotes atherogenesis and can lead to significant internal carotid artery stenosis (CAS) in older adults. This study found that CAS is associated with impaired cerebral vascular reactivity, but there were no significant differences in autoregulatory function or inter-hemispheric blood flow between symptomatic and asymptomatic CAS patients. Anatomically compromised circle of Willis did not significantly affect these parameters.
Article
Clinical Neurology
Qiuping Li, Yang Hua, Jiabin Liu, Fubo Zhou, Liyong Du, Jingzhi Li, Qing Li, Liqun Jiao
Summary: This study found that intraoperative TCD monitoring can help predict CHS after CEA at an early stage. The MCAV% values of CHS patients were significantly higher than non-CHS patients, and these values showed good accuracy in identifying CHS. Intraoperative TCD hemodynamic parameters play an important role in predicting CHS.
WORLD NEUROSURGERY
(2022)
Article
Clinical Neurology
Qiuping Li, Yang Hua, Jiabin Liu, Fubo Zhou, Liyong Du, Jingzhi Li, Qing Li, Liqun Jiao
Summary: This study found that intraoperative transcranial Doppler (TCD) monitoring can help predict cerebral hyperperfusion syndrome (CHS) after carotid endarterectomy (CEA) at an early stage.
WORLD NEUROSURGERY
(2022)
Article
Clinical Neurology
Guanxu Zhao, Guang Feng, Lei Zhao, Shuai Feng, Yi An, Cuicui Kong, Tianlong Wang
Summary: This study investigated the value of QEEG monitoring in Carotid Endarterectomy (CEA) and the thresholds for intraoperative cerebral perfusion-related ischemia monitoring. The results showed that QEEG is a promising monitoring method undergoing CEA under general anesthesia and has good consistency with TCD.
FRONTIERS IN NEUROLOGY
(2023)
Article
Acoustics
Jie Zhang, Lijuan Wang, Ying Chen, Sibo Wang, Li Cui
Summary: The aim of this study was to evaluate diffuse intracranial vertebrobasilar artery stenosis using ultrasonic examination with digital subtraction angiography as the reference. The study found that the consistency between ultrasonic examination and digital subtraction angiography for evaluating certain types of stenosis was not favorable. The study also identified the optimal low-velocity criteria for identifying critical and long stenosis in intracranial vertebrobasilar arteries.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2022)
Article
Surgery
Choshin Kim, Jun Lee, Se-Jin Lee, Woo-Sung Yun
Summary: The study aimed to evaluate the association between microembolic signals (MES) during carotid endarterectomy (CEA) and postoperative neurologic events or new brain lesions. Results showed MES were frequently found during CEA, but were not associated with new brain lesions.
ANNALS OF VASCULAR SURGERY
(2022)
Article
Surgery
Kara A. Rothenberg, Lue-Yen Tucker, Rebecca C. Gologorsky, Andrew L. Avins, Hui C. Kuang, Rishad M. Faruqi, Alexander C. Flint, Mai N. Nguyen-Huynh, Robert W. Chang
Summary: This study reports low rates of adverse events and long-term stroke risk up to 5 years following carotid endarterectomy (CEA) in a large health care system. The outcomes for both asymptomatic and symptomatic indications are within consensus guidelines and published trial outcomes, supporting the optimal use of CEA for severe carotid stenosis.
JOURNAL OF VASCULAR SURGERY
(2021)
Article
Clinical Neurology
Jinfeng Wang, Lanjun Guo, Robert N. Holdefer, Yansheng Zhang, Qin Liu, Qing Gai, Wengao Zhang
Summary: The study involving 152 patients undergoing carotid endarterectomy found that TCD is effective in detecting hypoperfusion and hyperperfusion, playing a key role in regulating blood pressure to prevent hyperperfusion.
WORLD NEUROSURGERY
(2021)
Article
Neurosciences
Efdal Akkaya, Bijen Nazliel, Hale Zeynep Caglayan Batur, Erhan Ilgit, Baran Onal, Koray Akkan, Ceyla Irkec
Summary: This study found significant increases in median CBFV and pulsatility index (PI) in the middle cerebral artery (MCA) bilaterally, especially on the stented side, measured 3 days and 3 months after stenting in patients with severe internal carotid artery stenosis.