Article
Medicine, General & Internal
Sergio Conti, Francesco Sabatino, Fabrizio Fortunato, Giuliano Ferrara, Antonio Cascino, Giuseppe Sgarito
Summary: This study aimed to evaluate the safety, effectiveness, and acute outcomes of high-power short-duration radiofrequency ablation in patients with persistent atrial fibrillation. The results showed that high-power short-duration radiofrequency ablation had similar success rates and shorter procedural time compared to the control group.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Christian-H Heeger, Makoto Sano, Sorin Stefan Popescu, Behnam Subin, Marcel Feher, Huong-Lan Phan, Bettina Kirstein, Julia Vogler, Charlotte Eitel, Sascha Hatahet, Karl-Heinz Kuck, Roland R. Tilz
Summary: This study evaluated the safety and efficacy of the vHP-SD ablation using a very-close protocol for pulmonary vein isolation (PVI) in the treatment of atrial fibrillation (AF) compared to standard ablation. The results showed that the vHP-SD ablation led to shorter procedure duration and ablation time, higher first-pass isolation rate, and promising 12-month follow-up and PVI durability.
Article
Medicine, General & Internal
Sebastian Weyand, Viola Adam, Matthias Beuter, Simon Hanger, David Heinzmann, Willibald Schrezenmeier, Peter Seizer
Summary: For patients undergoing radiofrequency pulmonary vein isolation, the necessity of pulmonary vein angiography was investigated after the use of high-resolution mapping catheters and high-power, short-duration ablation technique. The study found that omitting pulmonary vein angiography had no significant impact on the efficacy, efficiency, and complications of the ablation procedure. Therefore, avoiding pulmonary vein angiography may be useful, especially for young patients and those with chronic renal disease, when using this protocol.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Jonas Woermann, Jakob Lueker, Jan-Hendrik van den Bruck, Karlo Filipovic, Susanne Erlhoefer, Cornelia Scheurlen, Sebastian Dittrich, Jan-Hendrik Schipper, Daniel Steven, Arian Sultan
Summary: This study compared the efficacy and procedural differences between high power short duration radiofrequency ablation (HPSD) and cryoballoon ablation (CB) in the treatment of atrial fibrillation. The results showed that HPSD and CB had similar success rates and safety profiles, but HPSD had a longer procedure duration. In conclusion, HPSD is a feasible and effective option for the ablation treatment of atrial fibrillation.
CLINICAL RESEARCH IN CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Hanjin Park, Je-Wook Park, Daehoon Kim, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Boyoung Joung, Moon-Hyoung Lee, Chun Hwang, Hui-Nam Pak
Summary: This study compared the efficacy and safety of cryoballoon, high-power short-duration, and conventional radiofrequency ablation in treating atrial fibrillation. The results showed that the Cryo-PVI group had similar major complication and clinical recurrence rates compared to the other groups. However, the Cryo-PVI group had a lower risk of recurrent AF in patients with paroxysmal AF and a higher risk in patients with persistent AF. Additionally, the Cryo-PVI group had higher post-procedural sympathetic nervous activity and sympatho-vagal balance compared to the conventional-PVI group.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Alexander Francke, Frank Scharfe, Steffen Schoen, Carsten Wunderlich, Marian Christoph
Summary: High-power-short-duration radiofrequency technology is becoming a new standard of care in atrial fibrillation ablation, showing promising short-term efficacy. However, mid- to long-term effects are not well understood. Requiring reablation, patients mainly suffer from progressive fibrous atrial cardiomyopathy after HPSD ablation for pulmonary vein isolation and left atrial substrate modification.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Zoltan Sallo, Peter Perge, Bernadett Balogi, Gabor Orban, Katalin Piros, Szilvia Herczeg, Klaudia Vivien Nagy, Istvan Osztheimer, Pal abraham, Bela Merkely, Laszlo Geller, Nandor Szegedi
Summary: The study showed that high-power short-duration and very high-power short-duration radiofrequency ablation can shorten the procedure and radiofrequency time, increase the rate of first-pass isolation, and reduce the possibility of atrial fibrillation recurrence.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Medicine, General & Internal
Eduardo Celentano, Ernesto Cristiano, Barbara Ignatiuk, Elena Bia, Lorenzo Girotto, Nicola Tarantino, Natasja M. S. De Groot
Summary: Compared with standard radiofrequency ablation, the very high-power short-duration ablation technique showed shorter procedural time, total RF time, ablation phase time, and irrigation volume in the treatment of paroxysmal atrial fibrillation. In vHP-SD RF ablation, a minimum contact force of 5 g throughout the 4 s of RF application was significantly associated with an impedance drop of at least 10 Ohm. A maximum temperature and minimum contact force exceeding 5 g independently predicted an effective impedance drop in vHP-SD.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Sebastian Seidl, Tanja Muelleder, Josef Kaiblinger, Stefan Sieghartsleitner, Jasmina Alibegovic-Zaborsky, Elisabeth Sigmund, Michael Derndorfer, Georg Kollias, Helmut Puererfellner, Martin Martinek
Summary: This study compared the one-year outcome of very high power short-duration (HPSD) ablation with an ablation index (AI)-guided 50 Watt HPSD ablation strategy. The results showed comparable efficacy rates between the two approaches in terms of freedom from atrial fibrillation (AF) recurrence. Additionally, the very HPSD ablation approach was able to shorten ablation times and reduce radiation exposure without significantly increasing the rate of intraprocedural complications.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2022)
Article
Medicine, General & Internal
Julian Mueller, Karin Nentwich, Artur Berkovitz, Kai Sonne, Olena Kozlova, Sebastian Barth, Alexandru Deacanu, Christian Waechter, Philipp Halbfass, Heiko Lehrmann, Thomas Deneke
Summary: This study investigated the characteristics of patients undergoing redo AF ablation and the impact of different ablation strategies. The results showed that pulmonary vein reconnection was common among all techniques of AF ablation, and different ablation strategies did not improve long-term success.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Alexander Francke, Gregor Naumann, Marie-Christin Weidauer, Frank Scharfe, Steffen Schoen, Carsten Wunderlich, Marian Christoph
Summary: The use of high-power-short-duration radiofrequency ablation in atrial fibrillation treatment can reduce the incidence of esophageal injury, and additional posterior box isolation does not increase the risk of esophageal damage.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Naoko Hijioka, Takashi Kaneshiro, Takeshi Nehashi, Kazuaki Amami, Minoru Nodera, Shinya Yamada, Masashi Kamioka, Takafumi Ishida, Yasuchika Takeishi
Summary: This study investigated the safety and efficacy of high-power short-duration (HP-SD) ablation compared to conventional ablation in patients with atrial fibrillation. The results showed that the HP-SD group had a higher first pass isolation rate, fewer remaining gaps, and a shorter radiofrequency application time in each pulmonary vein.
BMC CARDIOVASCULAR DISORDERS
(2022)
Article
Cardiac & Cardiovascular Systems
Jean-Yves Wielandts, Maria Kyriakopoulou, Alexandre Almorad, Gabriela Hilfiker, Teresa Strisciuglio, Thomas Phlips, Milad El Haddad, Michelle Lycke, Philippe Unger, Jean-Benoit Le Polain De Waroux, Yves Vandekerckhove, Rene Tavernier, Mattias Duytschaever, Sebastien Knecht
Summary: The study on patients with paroxysmal AF using a 45W radiofrequency power CLOSE protocol significantly increased global procedural efficiency with similar midterm efficacy. However, there was a narrower safety margin and limited efficiency increase at the posterior wall using high power, advocating against high power use near the esophagus.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY
(2021)
Article
Medicine, General & Internal
Philippe Taghji, Jean-Claude Deharo, Sana Amraoui, Sok-Sithikun Bun
Summary: This study evaluated the efficacy of CLOSE-guided pulmonary vein isolation (PVI) in the treatment of persistent atrial fibrillation (AF). The results showed that CLOSE-guided PVI achieved a high single-procedure arrhythmia-free survival rate of 80% at 1 year under intensive cardiac rhythm monitoring. However, larger-scale studies are still needed to further confirm these findings.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Jonas Woermann, Jan-Hendrik Schipper, Jakob Lueker, Jan-Hendrik van den Bruck, Karlo Filipovic, Susanne Erlhoefer, Friederike Pavel, Cornelia Scheurlen, Sebastian Dittrich, Daniel Steven, Arian Sultan
Summary: This study compared procedural and outcome data for nonthermal pulsed field ablation (PFA) and very high power short duration ablation (VHPSD) in patients with atrial fibrillation. The results showed that both PFA and VHPSD are effective and safe for achieving pulmonary vein isolation (PVI) in patients with paroxysmal or persistent atrial fibrillation. However, PFA has a significantly shorter procedure duration, which may be beneficial.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2023)
Article
Cell Biology
Alexander Francke, Joerg Herold, Soenke Weinert, Ruth H. Strasser, Ruediger C. Braun-Dullaeus
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
(2011)
Article
Cardiac & Cardiovascular Systems
Joerg Herold, Alexander Francke, Soenke Weinert, Alexander Schmeisser, Katrin Hebel, Burkhart Schraven, Friedich-Wilhelm Roehl, Ruth H. Strasser, Ruediger C. Braun-Dullaeus
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2014)
Article
Multidisciplinary Sciences
Martin Wagner, Helen Koester, Christian Deffge, Soenke Weinert, Johannes Lauf, Alexander Francke, Jerry Lee, R. C. Braun-Dullaeus, Joerg Herold
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
(2014)
Article
Cardiac & Cardiovascular Systems
Marian Christoph, Akram Youssef, Jan Svitil, Mathias Forkmann, Yan Huo, Thomas Gaspar, Alexander Francke, Steffen Schoen, Silvio Quick, Carsten Wunderlich
Summary: This study aims to compare the efficiency and safety of uninterrupted DOAC therapy versus VKA during AF-Ablation in real world setting, with a focus on periinterventional heparin dosage.
CLINICAL CARDIOLOGY
(2021)
Article
Oncology
Joerg Herold, Steven Nowak, Sawa Kostin, Jan-Marcus Daniel, Alexander Francke, Saravanan Subramaniam, Ruediger C. Braun-Dullaeus, Sandip M. Kanse
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH
(2017)
Meeting Abstract
Cardiac & Cardiovascular Systems
J. Herold, C. Deffge, S. Nowak, M. Wagner, R. C. Braun-Dullaeus, S. Kostin, J. M. Daniel, A. Francke, S. Subramaniam, S. M. Kanse
CARDIOVASCULAR RESEARCH
(2016)
Meeting Abstract
Cardiac & Cardiovascular Systems
J. Herold, S. Nowak, A. Francke, S. Kanse, S. Weinert, R. C. Braun-Dullaeus
EUROPEAN HEART JOURNAL
(2011)
Article
Oncology
Alexander Francke, Soenke Weinert, Ruth H. Strasser, Ruediger C. Braun-Dullaeus, Joerg Herold
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH
(2013)