Analysis of the DNA-binding properties of Alx1, an evolutionarily conserved regulator of skeletogenesis in echinoderms

Transcription Factors of the Alx Family: Evolutionarily Conserved Regulators of Deuterostome Skeletogenesis

(2020) Jian Ming Khor et al.   Frontiers in Genetics

Identification of a novel homozygous ALX4 mutation in two unrelated patients with frontonasal dysplasia type-2

(2018) Mona El-Ruby et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

From Genome to Anatomy: The Architecture and Evolution of the Skeletogenic Gene Regulatory Network of Sea Urchins and Other Echinoderms

(2018) Tanvi Shashikant et al.   GENESIS

A massively parallel reporter assay reveals context-dependent activity of homeodomain binding sites in vivo

(2018) Andrew E.O. Hughes et al.   GENOME RESEARCH

Functional divergence of paralogous transcription factors supported the evolution of biomineralization in echinoderms

(2017) Jian Ming Khor et al.   eLife

Exome sequencing revealed a novel splice site variant in theALX1gene underlying frontonasal dysplasia

(2016) A. Ullah et al.   CLINICAL GENETICS

Experimental Approach Reveals the Role of alx1 in the Evolution of the Echinoderm Larval Skeleton

(2016) Hiroyuki Koga et al.   PLoS One

Syntax compensates for poor binding sites to encode tissue specificity of developmental enhancers

(2016) Emma K. Farley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

To Be Specific or Not: The Critical Relationship Between Hox And TALE Proteins

(2016) Samir Merabet et al.   TRENDS IN GENETICS

Low Affinity Binding Site Clusters Confer Hox Specificity and Regulatory Robustness

(2015) Justin Crocker et al.   CELL

Juvenile skeletogenesis in anciently diverged sea urchin clades

(2015) Feng Gao et al.   DEVELOPMENTAL BIOLOGY

Evolution of Darwin’s finches and their beaks revealed by genome sequencing

(2015) Sangeet Lamichhaney et al.   NATURE

Evolutionary rewiring of gene regulatory network linkages at divergence of the echinoid subclasses

(2015) Eric M. Erkenbrack et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide analysis of the skeletogenic gene regulatory network of sea urchins

(2014) K. Rafiq et al.   DEVELOPMENT

Vertical transmission of a frontonasal phenotype caused by a novelALX4mutation

(2013) Débora R Bertola et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Expression of skeletogenic genes during arm regeneration in the brittle star Amphiura filiformis

(2013) Anna Czarkwiani et al.   GENE EXPRESSION PATTERNS

BMP-2 Induced Expression of Alx3 That Is a Positive Regulator of Osteoblast Differentiation

(2013) Takashi Matsumoto et al.   PLoS One

Defective neural crest migration revealed by a Zebrafish model of Alx1-related frontonasal dysplasia

(2012) C. T. Dee et al.   HUMAN MOLECULAR GENETICS

Development of an embryonic skeletogenic mesenchyme lineage in a sea cucumber reveals the trajectory of change for the evolution of novel structures in echinoderms

(2012) Brenna S McCauley et al.   EvoDevo

The genomic regulatory control of skeletal morphogenesis in the sea urchin

(2011) K. Rafiq et al.   DEVELOPMENT

Disruption of ALX1 Causes Extreme Microphthalmia and Severe Facial Clefting: Expanding the Spectrum of Autosomal-Recessive ALX-Related Frontonasal Dysplasia

(2010) Elif Uz et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Scapula development is governed by genetic interactions of Pbx1 with its family members and with Emx2 via their cooperative control of Alx1

(2010) T. D. Capellini et al.   DEVELOPMENT

Frontorhiny, a Distinctive Presentation of Frontonasal Dysplasia Caused by Recessive Mutations in the ALX3 Homeobox Gene

(2009) Stephen R.F. Twigg et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Size and Shape of Protein Molecules at the Nanometer Level Determined by Sedimentation, Gel Filtration, and Electron Microscopy

(2009) Harold P. Erickson   BIOLOGICAL PROCEDURES ONLINE

Variation in Homeodomain DNA Binding Revealed by High-Resolution Analysis of Sequence Preferences

(2008) Michael F. Berger et al.   CELL

RESURRECTING THE ROLE OF TRANSCRIPTION FACTOR CHANGE IN DEVELOPMENTAL EVOLUTION

(2008) Vincent J. Lynch et al.   EVOLUTION

Transfer of a large gene regulatory apparatus to a new developmental address in echinoid evolution

(2008) F. Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA