The IgGFc-binding protein FCGBP is secreted with all GDPH sequences cleaved but maintained by interfragment disulfide bonds

Assembly Mechanism of Mucin and von Willebrand Factor Polymers

(2020) Gabriel Javitt et al.   CELL

The von Willebrand factor D'D3 assembly and structural principles for factor VIII binding and concatemer biogenesis

(2019) Xianchi Dong et al.   BLOOD

SignalP 5.0 improves signal peptide predictions using deep neural networks

(2019) José Juan Almagro Armenteros et al.   NATURE BIOTECHNOLOGY

Structural weakening of the colonic mucus barrier is an early event in ulcerative colitis pathogenesis

(2019) Sjoerd van der Post et al.   GUT

SUSD2 Proteolytic Cleavage Requires the GDPH Sequence and Inter-Fragment Disulfide Bonds for Surface Presentation of Galectin-1 on Breast Cancer Cells

(2019) Mitch E. Patrick et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antibiotic-induced changes in the microbiota disrupt redox dynamics in the gut

(2018) Aspen T Reese et al.   eLife

Calcium-activated Chloride Channel Regulator 1 (CLCA1) Controls Mucus Expansion in Colon by Proteolytic Activity

(2018) Elisabeth E.L. Nyström et al.   EBioMedicine

Internal cleavage and synergy with twisted gastrulation enhance BMP inhibition by BMPER

(2018) Michael P. Lockhart-Cairns et al.   MATRIX BIOLOGY

The Reduction-insensitive Bonds of the MUC2 Mucin Are Isopeptide Bonds

(2016) Christian V. Recktenwald et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Searching the Evolutionary Origin of Epithelial Mucus Protein Components—Mucins and FCGBP

(2016) Tiange Lang et al.   MOLECULAR BIOLOGY AND EVOLUTION

Normalization of Host Intestinal Mucus Layers Requires Long-Term Microbial Colonization

(2015) Malin E.V. Johansson et al.   Cell Host & Microbe

The Goblet Cell Protein Clca1 (Alias mClca3 or Gob-5) Is Not Required for Intestinal Mucus Synthesis, Structure and Barrier Function in Naive or DSS-Challenged Mice

(2015) Nancy A. Erickson et al.   PLoS One

von Willebrand factor, Jedi knight of the bloodstream

(2014) T. A. Springer   BLOOD

Microbial-induced meprin   cleavage in MUC2 mucin and a functional CFTR channel are required to release anchored small intestinal mucus

(2014) A. Schutte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Studies of mucus in mouse stomach, small intestine, and colon. II. Gastrointestinal mucus proteome reveals Muc2 and Muc5ac accompanied by a set of core proteins

(2013) Ana M. Rodríguez-Piñeiro et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Site-specificO-Glycosylation on the MUC2 Mucin Protein Inhibits Cleavage by thePorphyromonas gingivalisSecreted Cysteine Protease (RgpB)

(2013) Sjoerd van der Post et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the Repulsive Guidance Molecule (RGM)-Neogenin Signaling Hub

(2013) C. H. Bell et al.   SCIENCE

Sequence and structure relationships within von Willebrand factor

(2012) Y.-F. Zhou et al.   BLOOD

Role of oxygen gradients in shaping redox relationships between the human intestine and its microbiota

(2012) Michael Graham Espey   FREE RADICAL BIOLOGY AND MEDICINE

Platform-independent and Label-free Quantitation of Proteomic Data Using MS1 Extracted Ion Chromatograms in Skyline

(2012) Birgit Schilling et al.   MOLECULAR & CELLULAR PROTEOMICS

An ex vivo method for studying mucus formation, properties, and thickness in human colonic biopsies and mouse small and large intestinal explants

(2011) Jenny K. Gustafsson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Characterization of the Self-Cleaving Effector Protein NopE1 of Bradyrhizobium japonicum

(2011) J. Schirrmeister et al.   JOURNAL OF BACTERIOLOGY

Human Intestinal TFF3 Forms Disulfide-Linked Heteromers with the Mucus-Associated FCGBP Protein and Is Released by Hydrogen Sulfide

(2010) Timo K. Albert et al.   JOURNAL OF PROTEOME RESEARCH

Proteomic Analyses of the Two Mucus Layers of the Colon Barrier Reveal That Their Main Component, the Muc2 Mucin, Is Strongly Bound to the Fcgbp Protein

(2009) Malin E. V. Johansson et al.   JOURNAL OF PROTEOME RESEARCH

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

The BMP-Binding Protein Crossveinless 2 Is a Short-Range, Concentration-Dependent, Biphasic Modulator of BMP Signaling in Drosophila

(2008) Mihaela Serpe et al.   DEVELOPMENTAL CELL

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Phylogeny.fr: robust phylogenetic analysis for the non-specialist

(2008) A. Dereeper et al.   NUCLEIC ACIDS RESEARCH

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

(2008) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA