Journal
JOURNAL OF APPLIED POLYMER SCIENCE
Volume 138, Issue 44, Pages -Publisher
WILEY
DOI: 10.1002/app.51313
Keywords
biomaterials; degradation; differential scanning calorimetry; fibers; mechanical properties
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The aim of the study is to modulate the characteristics of electrospun scaffolds by selecting appropriate polymers, leading to better performance in terms of hydrophilicity and thermomechanical properties, with samples containing 3% cellulose nanocrystals and elastin peptide showing the best results.
Electrospun scaffolds can find numerous applications, including biomedical; for example, tissue engineering. Poly-L-lactic acid is considered suitable for these applications, but its low-thermal stability and its poor mechanical properties limit this polymer use. The aim of this work is to obtain a modulation of the final scaffolds characteristics such as fibers dimension, wettability, elasticity, and resistance to rupture through the choice of the polymers to be electrospun. Different electrospun scaffolds containing gelatin, Poly-DL-lactic acid, different percentages of cellulose nanocrystals and an elastin peptide have been produced. Thermal stability, physical structure, and its mechanical behavior have been studied. Results suggest that the electrospun scaffolds show better thermal and mechanical properties than bulk materials; that is, the scaffolds with the best hydrophilic and thermomechanical properties are the samples containing 3% (wt/wt) of CNCs and elastin peptide.
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