Electrophysiological Effects of the Transient Receptor Potential Melastatin 4 Channel Inhibitor (4-Chloro-2-(2-chlorophenoxy)acetamido) Benzoic Acid (CBA) in Canine Left Ventricular Cardiomyocytes

KCNQ1 G219E and TRPM4 T160M polymorphisms are involved in the pathogenesis of long QT syndrome

(2021) Yang Zhao et al.   MEDICINE

TRPM4 Participates in Aldosterone-Salt-Induced Electrical Atrial Remodeling in Mice

(2021) Christophe Simard et al.   Cells

Deletion of Trpm4 Alters the Function of the Nav1.5 Channel in Murine Cardiac Myocytes

(2021) Lijo Cherian Ozhathil et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ion current profiles in canine ventricular myocytes obtained by the “onion peeling” technique

(2021) Balázs Horváth et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

TRPM4 modulates right ventricular remodeling under pressure load accompanied with decreased expression level

(2020) Wiebke Frede et al.   JOURNAL OF CARDIAC FAILURE

Late sodium current in human, canine and guinea pig ventricular myocardium

(2020) Balázs Horváth et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

New role of TRPM4 channel in the cardiac excitation-contraction coupling in response to physiological and pathological hypertrophy in mouse

(2020) Christophe Hedon et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Inherited Cardiac Arrhythmia Syndromes: Focus on Molecular Mechanisms Underlying TRPM4 Channelopathies

(2020) Mohamed-Yassine Amarouch et al.   Cardiovascular Therapeutics

TRP Channels Expression Profile in Human End-Stage Heart Failure

(2019) Martin Dragún et al.   Medicina-Lithuania

AAV9-Mediated Overexpression of TRPM4 Increases the Incidence of Stress-Induced Ventricular Arrhythmias in Mice

(2019) Andy Pironet et al.   Frontiers in Physiology

Identification of potent and selective small molecule inhibitors of the cation channel TRPM4

(2018) Lijo Cherian Ozhathil et al.   BRITISH JOURNAL OF PHARMACOLOGY

Transient Receptor Potential Melastatin 4 channel inhibitor 9-phenanthrol inhibits K+ but not Ca2+ currents in canine ventricular myocytes

(2018) Roland Veress et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Functional characterization of TRPM4 variants identified in sudden unexpected natural death

(2018) Ekaterina Subbotina et al.   FORENSIC SCIENCE INTERNATIONAL

Ca 2+ -activated Cl − current is antiarrhythmic by reducing both spatial and temporal heterogeneity of cardiac repolarization

(2017) Bence Hegyi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The TRPM4 channel is functionally important for the beneficial cardiac remodeling induced by endurance training

(2017) Mélanie Gueffier et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

QT interval variability in body surface ECG: measurement, physiological basis, and clinical value: position statement and consensus guidance endorsed by the European Heart Rhythm Association jointly with the ESC Working Group on Cardiac Cellular Electrophysiology

(2016) Mathias Baumert et al.   EUROPACE

Sarcolemmal Ca 2+ -entry through L-type Ca 2+ channels controls the profile of Ca 2+ -activated Cl − current in canine ventricular myocytes

(2016) Balázs Horváth et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Role of TRP channels in the cardiovascular system

(2015) Zhichao Yue et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The Ca2+-activated cation channel TRPM4 is a negative regulator of angiotensin II-induced cardiac hypertrophy

(2015) Miklós Kecskés et al.   BASIC RESEARCH IN CARDIOLOGY

TRPM4 non-selective cation channels influence action potentials in rabbit Purkinje fibres

(2015) Thomas Hof et al.   JOURNAL OF PHYSIOLOGY-LONDON

Transient Receptor Potential Melastatin-4 Is Involved in Hypoxia-Reoxygenation Injury in the Cardiomyocytes

(2015) Hulin Piao et al.   PLoS One

The TRPM4 channel inhibitor 9-phenanthrol

(2014) R Guinamard et al.   BRITISH JOURNAL OF PHARMACOLOGY

P2Y1receptor-mediated potentiation of inspiratory motor output in neonatal ratin vitro

(2014) T. S. Alvares et al.   JOURNAL OF PHYSIOLOGY-LONDON

Contribution of ion currents to beat-to-beat variability of action potential duration in canine ventricular myocytes

(2014) Norbert Szentandrássy et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Trpm4 Gene Invalidation Leads to Cardiac Hypertrophy and Electrophysiological Alterations

(2014) Marie Demion et al.   PLoS One

9-Phenanthrol and flufenamic acid inhibit calcium oscillations in HL-1 mouse cardiomyocytes

(2013) Rees Burt et al.   CELL CALCIUM

Increased β-Adrenergic Inotropy in Ventricular Myocardium From Trpm4 −/− Mice

(2013) Ilka Mathar et al.   CIRCULATION RESEARCH

Implication of the TRPM4 nonselective cation channel in mammalian sinus rhythm

(2013) Thomas Hof et al.   HEART RHYTHM

The TRPM4 non-selective cation channel contributes to the mammalian atrial action potential

(2013) Christophe Simard et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Biochemical, single-channel, whole-cell patch clamp, and pharmacological analyses of endogenous TRPM4 channels in HEK293 cells

(2013) Mohamed-Yassine Amarouch et al.   NEUROSCIENCE LETTERS

Molecular Genetics and Functional Anomalies in a Series of 248 Brugada Cases with 11 Mutations in the TRPM4 Channel

(2013) Hui Liu et al.   PLoS One

Evidence for functional expression of TRPM7 channels in human atrial myocytes

(2012) Yan-Hui Zhang et al.   BASIC RESEARCH IN CARDIOLOGY

Arrhythmogenic mechano-electric heterogeneity in the long-QT syndrome

(2012) Rachel M.A. ter Bekke et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Transient receptor potential melastatin 4 inhibitor 9-phenanthrol abolishes arrhythmias induced by hypoxia and re-oxygenation in mouse ventricle

(2011) Christophe Simard et al.   BRITISH JOURNAL OF PHARMACOLOGY

Endogenous cytosolic Ca2+ buffering is necessary for TRPM4 activity in cerebral artery smooth muscle cells

(2011) Albert L. Gonzales et al.   CELL CALCIUM

Profile of L-type Ca2+ current and Na+/Ca2+ exchange current during cardiac action potential in ventricular myocytes

(2011) Tamas Banyasz et al.   HEART RHYTHM

Mutational spectrum in the Ca2+-activated cation channel gene TRPM4 in patients with cardiac conductance disturbances

(2011) Birgit Stallmeyer et al.   HUMAN MUTATION

Calcium-activated non-selective cation currents are involved in generation of tonic and bursting activity in dopamine neurons of the substantia nigra pars compacta

(2011) Ana Mrejeru et al.   JOURNAL OF PHYSIOLOGY-LONDON

Microdomain [Ca2+] near ryanodine receptors as reported by L-type Ca2+and Na+/Ca2+exchange currents

(2011) Karoly Acsai et al.   JOURNAL OF PHYSIOLOGY-LONDON

Gain-of-Function Mutations in TRPM4 Cause Autosomal Dominant Isolated Cardiac Conduction Disease

(2010) Hui Liu et al.   Circulation-Cardiovascular Genetics

Possible mechanisms of sudden cardiac death in top athletes: a basic cardiac electrophysiological point of view

(2010) András Varró et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The Pathological Role of Transient Receptor Potential Channels in Heart Disease

(2009) Hiroyuki Watanabe et al.   CIRCULATION JOURNAL

Impaired endocytosis of the ion channel TRPM4 is associated with human progressive familial heart block type I

(2009) Martin Kruse et al.   JOURNAL OF CLINICAL INVESTIGATION

IKs restricts excessive beat-to-beat variability of repolarization during beta-adrenergic receptor stimulation

(2009) Daniel M. Johnson et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Endogenous TRPM4-like channel in Chinese hamster ovary (CHO) cells

(2008) Oleg V. Yarishkin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

9-Phenanthrol inhibits human TRPM4 but not TRPM5 cationic channels

(2008) T Grand et al.   BRITISH JOURNAL OF PHARMACOLOGY

Calcium Cycling and Signaling in Cardiac Myocytes

(2007) Donald M. Bers   Annual Review of Physiology