Ncx3-Induced Mitochondrial Dysfunction in Midbrain Leads to Neuroinflammation in Striatum of A53t-α-Synuclein Transgenic Old Mice

Mitochondrial Behavior in Axon Degeneration and Regeneration

(2021) Biyao Wang et al.   Frontiers in Aging Neuroscience

Nuclear-encoded NCX3 and AKAP121: two novel modulators of mitochondrial calcium efflux in normoxic and hypoxic neurons

(2020) Maria Josè Sisalli et al.   CELL CALCIUM

Mitochondrial Dysfunctions: A Red Thread across Neurodegenerative Diseases

(2020) Serena Stanga et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial Homeostasis and Signaling in Parkinson’s Disease

(2020) Antonella Scorziello et al.   Frontiers in Aging Neuroscience

NCX1 and NCX3 as potential factors contributing to neurodegeneration and neuroinflammation in the A53T transgenic mouse model of Parkinson’s Disease

(2018) Rossana Sirabella et al.   Cell Death & Disease

Selective neuronal vulnerability in Parkinson disease

(2017) D. James Surmeier et al.   NATURE REVIEWS NEUROSCIENCE

Interaction of α-synuclein with biomembranes in Parkinson's disease —role of cardiolipin

(2016) Stephanie Ghio et al.   PROGRESS IN LIPID RESEARCH

Pharmacological Characterization of the Newly Synthesized 5-Amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide Hydrochloride (BED) as a Potent NCX3 Inhibitor That Worsens Anoxic Injury in Cortical Neurons, Organotypic Hippocampal Cultures, and Ischemic Brain

(2015) Agnese Secondo et al.   ACS Chemical Neuroscience

Elevated Mitochondrial Bioenergetics and Axonal Arborization Size Are Key Contributors to the Vulnerability of Dopamine Neurons

(2015) Consiglia Pacelli et al.   CURRENT BIOLOGY

Endoplasmic reticulum refilling and mitochondrial calcium extrusion promoted in neurons by NCX1 and NCX3 in ischemic preconditioning are determinant for neuroprotection

(2014) M J Sisalli et al.   CELL DEATH AND DIFFERENTIATION

Inhibition of Neuroinflammation and Mitochondrial Dysfunctions by Carbenoxolone in the Rotenone Model of Parkinson’s Disease

(2014) Poonam Thakur et al.   MOLECULAR NEUROBIOLOGY

Systemic injection of LPS induces region-specific neuroinflammation and mitochondrial dysfunction in normal mouse brain

(2014) Haneul Noh et al.   NEUROCHEMISTRY INTERNATIONAL

Calcium and Endoplasmic Reticulum-Mitochondria Tethering in Neurodegeneration

(2013) Tito Calì et al.   DNA AND CELL BIOLOGY

NCX3 regulates mitochondrial Ca 2+ handling through the AKAP121-anchored signaling complex and prevents hypoxia-induced neuronal death

(2013) Antonella Scorziello et al.   JOURNAL OF CELL SCIENCE

Mitochondrial dynamics modulate the expression of pro-inflammatory mediators in microglial cells

(2013) Junghyung Park et al.   JOURNAL OF NEUROCHEMISTRY

Calcium Entry and  -Synuclein Inclusions Elevate Dendritic Mitochondrial Oxidant Stress in Dopaminergic Neurons

(2013) D. I. Dryanovski et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial Ca2+ and neurodegeneration

(2012) Tito Calì et al.   CELL CALCIUM

Assessing Activation States in Microglia

(2012) Carol A. Colton et al.   CNS & Neurological Disorders-Drug Targets

A New Concept: A 1-42 Generates a Hyperfunctional Proteolytic NCX3 Fragment That Delays Caspase-12 Activation and Neuronal Death

(2012) A. Pannaccione et al.   JOURNAL OF NEUROSCIENCE

Proteasome Inhibition Alleviates SNARE-Dependent Neurodegeneration

(2012) M. Sharma et al.   Science Translational Medicine

The role of calcium and mitochondrial oxidant stress in the loss of substantia nigra pars compacta dopaminergic neurons in Parkinson's disease

(2011) D.J. Surmeier et al.   NEUROSCIENCE

Neuroinflammation in Parkinson's disease

(2011) Etienne C. Hirsch et al.   PARKINSONISM & RELATED DISORDERS

Immune response by microglia in the spinal cord

(2010) Julie K. Olson   Annals of the New York Academy of Sciences

Mitochondria and Neuroplasticity

(2010) Aiwu Cheng et al.   ASN Neuro

Mechanisms Underlying Inflammation in Neurodegeneration

(2010) Christopher K. Glass et al.   CELL

Calcium, cellular aging, and selective neuronal vulnerability in Parkinson's disease

(2010) D. James Surmeier et al.   CELL CALCIUM

Effects of mitochondrial dysfunction on the immunological properties of microglia

(2010) Annette I Ferger et al.   Journal of Neuroinflammation

Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1

(2010) Jaime N. Guzman et al.   NATURE

Gait dynamics in Parkinson’s disease: Common and distinct behavior among stride length, gait variability, and fractal-like scaling

(2009) Jeffrey M. Hausdorff   CHAOS

Dopamine and synaptic plasticity in dorsal striatal circuits controlling action selection

(2009) D James Surmeier et al.   CURRENT OPINION IN NEUROBIOLOGY

Neuroinflammation in Parkinson’s Disease

(2009) Jae-Kyung Lee et al.   Journal of Neuroimmune Pharmacology

Serum levels of brain-derived neurotrophic factor correlate with motor impairment in Parkinson’s disease

(2009) Paula Scalzo et al.   JOURNAL OF NEUROLOGY

The role of α-synuclein in brain lipid metabolism: a downstream impact on brain inflammatory response

(2009) Mikhail Y. Golovko et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Primary support cultures of hippocampal and substantia nigra neurons

(2009) Thomas Fath et al.   Nature Protocols

Neuroinflammation in Parkinson's disease: Its role in neuronal death and implications for therapeutic intervention

(2009) Malú G. Tansey et al.   NEUROBIOLOGY OF DISEASE

Anoxia-Induced NF-kB-Dependent Upregulation of NCX1 Contributes to Ca 2+ Refilling Into Endoplasmic Reticulum in Cortical Neurons

(2009) Rossana Sirabella et al.   STROKE

NCX1 Expression and Functional Activity Increase in Microglia Invading the Infarct Core

(2009) Francesca Boscia et al.   STROKE

Calcium homeostasis, selective vulnerability and Parkinson's disease

(2009) C. Savio Chan et al.   TRENDS IN NEUROSCIENCES

Targeted Disruption of Na+/Ca2+ Exchanger 3 (NCX3) Gene Leads to a Worsening of Ischemic Brain Damage

(2008) P. Molinaro et al.   JOURNAL OF NEUROSCIENCE

Glial reactions in Parkinson's disease

(2007) Patrick L. McGeer et al.   MOVEMENT DISORDERS