Ganciclovir and Its Hemocompatible More Lipophilic Derivative Can Enhance the Apoptotic Effects of Methotrexate by Inhibiting Breast Cancer Resistance Protein (BCRP)

Multidrug resistance proteins (MRPs): Structure, function and the overcoming of cancer multidrug resistance

(2021) Jing-Quan Wang et al.   DRUG RESISTANCE UPDATES

Identification of molecular fingerprints of natural products for the inhibition of breast cancer resistance protein (BCRP)

(2021) Arghya Banik et al.   PHYTOMEDICINE

Structural Basis of Drug Recognition by the Multidrug Transporter ABCG2

(2021) Julia Kowal et al.   JOURNAL OF MOLECULAR BIOLOGY

The ABCG2/BCRP transporter and its variants – from structure to pathology

(2020) Balázs Sarkadi et al.   FEBS LETTERS

L-Type Amino Acid Transporter 1 Enables the Efficient Brain Delivery of Small-Sized Prodrug across the Blood–Brain Barrier and into Human and Mouse Brain Parenchymal Cells

(2020) Ahmed B. Montaser et al.   ACS Chemical Neuroscience

Sulfenamide derivatives can improve transporter-mediated cellular uptake of metformin and induce cytotoxicity in human breast adenocarcinoma cell lines

(2019) Magdalena Markowicz-Piasecka et al.   BIOORGANIC CHEMISTRY

Concomitant febuxostat enhances methotrexate-induced hepatotoxicity by inhibiting breast cancer resistance protein

(2019) Kenji Ikemura et al.   Scientific Reports

Biocompatible sulfenamide and sulfonamide derivatives of metformin can exert beneficial effects on plasma haemostasis

(2018) Magdalena Markowicz-Piasecka et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Targeted efflux transporter inhibitors – A solution to improve poor cellular accumulation of anti-cancer agents

(2018) Johanna Huttunen et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

New prodrugs of metformin do not influence the overall haemostasis potential and integrity of the erythrocyte membrane

(2017) Magdalena Markowicz-Piasecka et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Coupling to a cancer-selective heparan-sulfate-targeted branched peptide can by-pass breast cancer cell resistance to methotrexate

(2017) Lorenzo Depau et al.   Oncotarget

Overcoming ABC transporter-mediated multidrug resistance: Molecular mechanisms and novel therapeutic drug strategies

(2016) Wen Li et al.   DRUG RESISTANCE UPDATES

Triple negative breast cancer development can be selectively suppressed by sustaining an elevated level of cellular cyclic AMP through simultaneously blocking its efflux and decomposition

(2016) Wei Wang et al.   Oncotarget

Multiple drug resistance-associated protein (MRP4) exports prostaglandin E2 (PGE2) and contributes to metastasis in basal/triple negative breast cancer

(2016) Tyler J. Kochel et al.   Oncotarget

Adenovirus-mediated gene therapy with sitimagene ceradenovec followed by intravenous ganciclovir for patients with operable high-grade glioma (ASPECT): a randomised, open-label, phase 3 trial

(2013) Manfred Westphal et al.   LANCET ONCOLOGY

The art of gene therapy for glioma: a review of the challenging road to the bedside

(2012) Alex Tobias et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Expression levels of multidrug resistance-associated protein 4 (MRP4) in human leukemia and lymphoma cell lines, and the inhibitory effects of the MRP-specific inhibitor MK-571 on methotrexate distribution in rats

(2012) KENJI TAKEUCHI et al.   Experimental and Therapeutic Medicine

Overcoming drug efflux-based multidrug resistance in cancer with nanotechnology

(2012) Xue Xue et al.   Chinese Journal of Cancer

Biocompatibility and characteristics of injectable chitosan-based thermosensitive hydrogel for drug delivery

(2010) Hui Yun Zhou et al.   CARBOHYDRATE POLYMERS

Side populations of glioblastoma cells are less sensitive to HSV-TK/GCV suicide gene therapy system than the non-side population

(2010) Weiwei Hu et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Contribution of the drug transporter ABCG2 (breast cancer resistance protein) to resistance against anticancer nucleosides

(2008) C. de Wolf et al.   MOLECULAR CANCER THERAPEUTICS