Article
Infectious Diseases
Maryam Nasiri, Javad Khodadadi, Sedigheh Molaei
Summary: This study found a significant association between vitamin D levels and hospital stay in COVID-19 patients, but no significant relationship with death rate or time to return to normal oxygen levels.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2021)
Review
Medicine, General & Internal
Sreedhar Subramanian, George Griffin, Martin Hewison, Julian Hopkin, Rose Anne Kenny, Eamon Laird, Richard Quinton, David Thickett, Jonathan M. Rhodes
Summary: Vitamin D deficiency is associated with an increased risk of COVID-19, especially in winter or among individuals with less sunlight exposure or darker skin pigmentation. Some studies have shown an association between vitamin D deficiency and increased severity of COVID-19, but the results of interventional studies are inconclusive.
JOURNAL OF INTERNAL MEDICINE
(2022)
Article
Geriatrics & Gerontology
S. Karahan, F. Katkat
Summary: This study investigated the role of serum 25(OH) vitamin D level on COVID severity and related mortality in 149 COVID-19 patients, revealing that serum 25(OH) vitamin D was independently associated with mortality.
JOURNAL OF NUTRITION HEALTH & AGING
(2021)
Article
Nutrition & Dietetics
Magdalena Basinska-Lewandowska, Krzysztof Lewandowski, Wojciech Horzelski, Andrzej Lewinski, Elzbieta Skowronska-Jozwiak
Summary: The study found a correlation between 25OHD concentrations below 12 ng/mL and an increased risk of COVID-19 infection. However, no significant increase in infection risk was observed for individuals with 25OHD concentrations above 20 ng/mL.
Article
Immunology
Yongbiao Huang, Ye Yuan, Sheng Chen, Duo Xu, Lingyan Xiao, Xi Wang, Wan Qin, Bo Liu
Summary: This study aimed to investigate the therapeutic effects and underlying action mechanisms of vitamin D in COVID-19 and HCC. Through bioinformatics and network pharmacology analyses, we identified target genes and analyzed their prognostic significance in HCC patients. We developed a risk score model to evaluate the prognosis of HCC patients with COVID-19 and identified seven potential pharmacological targets of vitamin D. We also revealed the biological functions, signaling pathways, and TF-miRNA coregulatory network of vitamin D in COVID-19/HCC.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Nutrition & Dietetics
Sreedhar Subramanian, Jonathan M. Rhodes, Joseph M. Taylor, Anna M. Milan, Steven Lane, Martin Hewison, Rene F. Chun, Andrea Jorgensen, Paul Richardson, Darshan Nitchingham, Joseph Aslan, Maya Shah, Coonoor R. Chandrasekar, Amanda Wood, Mike Beadsworth, Munir Pirmohamed
Summary: Vitamin D status is not significantly associated with mortality from COVID-19, but extremely low and high levels may be associated with mortality risks.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Nutrition & Dietetics
Alberto Sulli, Emanuele Gotelli, Andrea Casabella, Sabrina Paolino, Carmen Pizzorni, Elisa Alessandri, Marco Grosso, Diego Ferone, Vanessa Smith, Maurizio Cutolo
Summary: The study demonstrates that vitamin D deficiency in COVID-19 patients is associated with severe lung involvement, longer disease duration, and higher risk of death, particularly in elderly patients. Low vitamin D levels are negatively correlated with the severity of radiologic pulmonary involvement.
Review
Endocrinology & Metabolism
Andrea Giustina
Summary: The review suggests that there may be an endocrine phenotype related to COVID-19, with a correlation between 25 hydroxyvitamin D levels and different clinical outcomes of the disease. Therefore, various endocrine manifestations of COVID-19 could potentially be explained in the context of inadequate vitamin D status.
Review
Medicine, General & Internal
K. Shah, V. P. Varna, A. Pandya, D. Saxena
Summary: The study revealed that nearly half of pediatric COVID patients suffer from vitamin D deficiency, and low levels of vitamin D are associated with increased risk of infection and poorer outcomes.
QJM-AN INTERNATIONAL JOURNAL OF MEDICINE
(2021)
Article
Nutrition & Dietetics
Martyna Jasielska, Urszula Grzybowska-Chlebowczyk
Summary: The study found that the incidence of hypocalcemia and vitamin D deficiency is higher in children with inflammatory bowel diseases and lactose intolerance. However, the use of a low-lactose diet did not have a significant impact on these conditions.
Review
Health Care Sciences & Services
Hiwot Yisak, Amien Ewunetei, Belayneh Kefale, Melkalem Mamuye, Fentaw Teshome, Birhanie Ambaw, Getachew Yideg Yitbarek
Summary: Vitamin D status is associated with risks of influenza and respiratory tract infections, particularly against enveloped viruses like coronavirus. Studies show that maintaining sufficient levels of vitamin D can affect COVID-19 infection, severity, and mortality rates.
RISK MANAGEMENT AND HEALTHCARE POLICY
(2021)
Article
Endocrinology & Metabolism
Sima Hashemipour, Somaieh Kiani, Pouria Shahsavari, Sabereh Afshar, Arefeh Ghobadi, Seyyed Mohammad Reza Hadizadeh Khairkhahan, Milad Badri, Seyed Saeed Farzam, Hossein Sohrabi, Mahyar Seddighi, Rozita Bahadori
Summary: This study evaluated the etiologies of hypocalcemia in COVID-19 patients and found that vitamin D deficiency plays a major role. The findings also suggest that inappropriately low/low-normal serum PTH may contribute to this disorder.
JOURNAL OF BONE AND MINERAL METABOLISM
(2022)
Review
Pharmacology & Pharmacy
James Bernard Walsh, Daniel M. McCartney, Eamon Laird, Kevin McCarroll, Declan G. Byrne, Martin Healy, Paula M. O'Shea, Rose Anne Kenny, John L. Faul
Summary: This review examines the association between vitamin D, SARS-CoV-2 infection, and COVID-19 severity. The authors conclude that there is a causal relationship between low vitamin D status and increased risk of infection and severe COVID-19. They suggest that vitamin D supplementation may be beneficial for improving immunity against SARS-CoV-2, especially in vulnerable populations. The study highlights the prevalence of low vitamin D status among Irish adults.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Nutrition & Dietetics
Emanuele Cereda, Laura Bogliolo, Catherine Klersy, Federica Lobascio, Sara Masi, Silvia Crotti, Ludovico De Stefano, Raffaele Bruno, Angelo Guido Corsico, Antonio Di Sabatino, Stefano Perlini, Carlomaurizio Montecucco, Riccardo Caccialanza
Summary: In this study of COVID-19 patients admitted to an Italian referral hospital, there was a high prevalence of 25(OH)vitamin D deficiency, but low levels were not associated with clinical outcomes. Surprisingly, higher 25(OH)vitamin D levels were positively correlated with in-hospital mortality. This suggests a complex relationship between vitamin D levels and COVID-19 severity that requires further investigation.
CLINICAL NUTRITION
(2021)
Article
Infectious Diseases
Justyna Malinowska, Milena Malecka-Gieldowska, Diana Bankowska, Kinga Borecka, Olga Ciepiela
Summary: Nonrespiratory manifestations of COVID-19, including endocrine disorders, can affect calcium-magnesium-phosphate homeostasis and impact disease severity and patient outcomes. This study found that hypermagnesemia and hyperphosphatemia were associated with increased risk of death in COVID-19 patients, while hypovitaminosis D3 was also linked to higher mortality. Routine monitoring of these parameters, especially in patients with decreased kidney function, is recommended.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Toxicology
Badria Alhatali, Sultan Al Lawatia, Faryal Khamis, Sandeep Kantur, Seif Al-Abri, Vikas Kapil, Jerry Thomas, Rudolph Johnson, Elizabeth Hamelin, Rebecca M. Coleman, Ziad Kazzi
Summary: This report describes five cases of tetrodotoxin poisoning in patients who consumed fried internal organs of local pufferfish from the coast of Oman. Patients exhibited typical TTX toxidrome symptoms, with most recovering completely, except for one patient who developed subarachnoid hemorrhage related to TTX poisoning, a complication not previously reported.
CLINICAL TOXICOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Jameela Al Salman, Laila Al Dabal, Matteo Bassetti, Wadha A. Alfouzan, Muna Al Maslamani, Basem Alraddadi, Ashraf Elhoufi, Faryal Khamis, Eiman Mokkadas, Ingy Romany, Mushira Enani, Ali Somily, Souha S. Kanj
Summary: Antimicrobial resistance is a significant global issue, with a particular impact in the Middle East where the emergence of multi-drug resistant organisms poses a major challenge. A Working Group of experts from Arab countries in the Middle East identified differences in awareness of local epidemiology, management of multi-drug resistant organisms, and antimicrobial stewardship practices. Urgent action is needed to address barriers to effective management and promote strategies for antimicrobial stewardship in the region, focusing on training, education, capacity building, infrastructure, regional research, and surveillance.
JOURNAL OF INFECTION AND PUBLIC HEALTH
(2021)
Article
Infectious Diseases
Asma Al Balushi, Jalila AlShekaili, Mahmood Al Kindi, Zainab Ansari, Murtadha Al-Khabori, Faryal Khamis, Zaiyana Ambusaidi, Afra Al Balushi, Aisha Al Huraizi, Sumaiya Al Sulaimi, Fatma Al Fahdi, Iman Al Balushi, Nenad Pandak, Tom Fletcher, Iman Nasr
Summary: Identifying immune cells and predictors of poor outcomes in COVID-19 is crucial. This study found that hospitalized patients had higher levels of inflammatory markers and certain immune cells were independent predictors of ICU admission or death.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Public, Environmental & Occupational Health
Faryal Khamis, Ziad Memish, Maher Al Bahrani, Samata Al Dowaiki, Nenad Pandak, Zakaryia Al Bolushi, Issa Al Salmi, Ibrahim Al-Zakwani
Summary: The study identified a high mortality rate among COVID-19 patients in a hospital in Oman, with factors such as advanced age, heart disease, liver disease, high ferritin levels, ARDS, sepsis, and ICU admission being associated with mortality.
JOURNAL OF INFECTION AND PUBLIC HEALTH
(2021)
Article
Medicine, General & Internal
Bassim Jaffar Al Bahrani, Itrat Mehdi, Faryal Ali Khamis, Abdulaziz Mohammed Al Farsi, Fatma Al Fandi, Najla Ali Al Lawati
Summary: This study evaluated the extent of coronavirus infection in cancer patients in a tertiary care setting in Oman from March to October 2020. The data showed that 0.47% of cancer patients were infected with COVID-19, with a high mortality rate of 35.1%. Cancer patients with COVID-19 also had comorbidities such as diabetes, hypertension, renal complications, and cardiac issues.
JOURNAL OF THE PAKISTAN MEDICAL ASSOCIATION
(2021)
Article
Emergency Medicine
Massimo Sartelli, Francesco M. Labricciosa, Federico Coccolini, Raul Coimbra, Fikri M. Abu-Zidan, Luca Ansaloni, Majdi N. Al-Hasan, Shamshul Ansari, Philip S. Barie, Miguel Angel Cainzos, Marco Ceresoli, Massimo Chiarugi, Jeffrey A. Claridge, Enrico Cicuttin, Evan Patchen Dellinger, Donald E. Fry, Xavier Guirao, Timothy Craig Hardcastle, Andreas Hecker, Ari K. Leppaniemi, Andrey Litvin, Sanjay Marwah, Emilio Maseda, John E. Mazuski, Ziad Ahmed Memish, Andrew W. Kirkpatrick, Leonardo Pagani, Mauro Podda, Huseyin Kemal Rasa, Boris E. Sakakushev, Robert G. Sawyer, Fabio Tumietto, Yonghong Xiao, Wedad Faraj Aboubreeg, Harissou Adamou, Lali Akhmeteli, Emrah Akin, Maria Grazia Alberio, Felipe Alconchel, Ibrahim Amadou Magagi, Ana Belen Arauz, Giulio Argenio, Boyko C. Atanasov, Semra Demirli Atici, Selmy Sabry Awad, Efstratia Baili, Lovenish Bains, Miklosh Bala, Oussama Baraket, Suman Baral, Vladislav A. Belskii, Moussa Benboubker, Offir Ben-Ishay, Pierpaolo Bordoni, Abdalia Boumediene, Giuseppe Brisinda, Laura Cavazzuti, Sujith J. Chandy, Maria Michela Chiarello, Nicola Cillara, Guglielmo Clarizia, Maria-Elena Cocuz, Iuliu Gabriel Cocuz, Luigi Conti, Raffaella Coppola, Yunfeng Cui, Jacek Czepiel, Fabrizio D'Acapito, Dimitrios Damaskos, Koray Das, Belinda De Simone, Samir Delibegovic, Zaza Demetrashvili, Dzemail S. Detanac, Sameer Dhingra, Stefano Di Bella, Evgeni N. Dimitrov, Agron Dogjani, Mario D'Oria, Irina Magdalena Dumitru, Mutasim M. Elmangory, Octavian Enciu, Massimo Fantoni, Daniela Filipescu, Francesco Fleres, Domitilla Foghetti, Pietro Fransvea, Mahir Gachabayov, Rita Galeiras, Gianni Gattuso, Wagih M. Ghannam, Valeria Ghisetti, Giorgio Giraudo, Kebebe Bekele Gonfa, Emre Gonullu, Yousif Tag Elsir Y. Hamad, Matthias Hecker, Arda Isik, Nizar Ismail, Azzain Ismail, Sumita Agarwal Jain, Souha S. Kanj, Garima Kapoor, Ilias Karaiskos, Alfie J. Kavalakat, Jakub Kenig, Faryal Khamis, Vladimir Khokha, Ronald Kiguba, Jae Il Kim, Yoshiro Kobe, Kenneth Yuh Yen Kok, Bojan M. Kovacevic, Igor Andreevich Kryvoruchko, Akira Kuriyama, Aitor Landaluce-Olavarria, Konstantinos Lasithiotakis, Varut Lohsiriwat, Eftychios Lostoridis, Davide Luppi, Gustavo Miguel Machain Vega, Marc Maegele, Athanasios Marinis, Gennaro Martines, Aleix Martinez-Perez, Damien Massalou, Cristian Mesina, Gokhan Metan, Maria Guadalupe Miranda-Novales, Shyam Kumar Mishra, Mohaned Ibrahim Hussein Mohamed, Ali Yasen Y. Mohamedahmed, Ismael Mora-Guzman, Francesk Mulita, Ana-Maria Musina, Pradeep H. Navsaria, Ionut Negoi, Gabriela Elisa Nita, Donal B. O'Connor, Carlos Alberto Ordonez, Desire Pantalone, Arpad Panyko, Aristeidis Papadopoulos, Nikolaos Pararas, Francesco Pata, Tapan Patel, Gianluca Pellino, Teresa Perra, Gennaro Perrone, Antonio Pesce, Tadeja Pintar, Georgi Ivanov Popivanov, Alberto Porcu, Martha Alexa Quiodettis, Razrim Rahim, Ashrarur Rahman Mitul, Martin Reichert, Miran Rems, Glendee Yolande Reynolds Campbell, Nuno Rocha-Pereira, Gabriel Rodrigues, Gustavo Eduardo Roncancio Villamil, Stefano Rossi, Ibrahima Sall, Hossein Samadi Kafil, Diego Sasia, Jeremiah Seni, Charalampos Seretis, Mario Serradilla-Martin, Vishal G. Shelat, Boonying Siribumrungwong, Mihail Slavchev, Leonardo Solaini, Boun Kim Tan, Antonio Tarasconi, Dario Tartaglia, Elena Adelina Toma, Gia Tomadze, Adriana Toro, Marcos Roberto Tovani-Palone, Harry van Goor, Alin Vasilescu, Andras Vereczkei, Massimiliano Veroux, Sergio Alberto Weckmann, Lukas Werner Widmer, AliIbrahim Yahya, Sanoop K. Zachariah, Andee Dzulkarnaen Zakaria, Nadezhda Zubareva, Wietse P. Zuidema, Isidoro Di Carlo, Francesco Cortese, Gian Luca Baiocchi, Ronald Maier, Fausto Catena
Summary: This study investigated the organizational characteristics of acute care facilities worldwide in preventing and managing infections in surgery, and assessed participants' perception regarding infection prevention and control measures. The results showed that patient involvement in IPC implementation is still not well-considered, and the COVID-19 pandemic has played a significant role in increasing awareness among HCWs of IPC programs.
WORLD JOURNAL OF EMERGENCY SURGERY
(2022)
Article
Medicine, Research & Experimental
Faryal Khamis, Salah Al Awaidy, Muna Ba'Omar, Wessam Osman, Shabnam Chhetri, Zaiyana Ambusaid, Zakariya Al Fahdi, Jaber Al Lawati, Khalsa Al Sulaimi, Salma Ali Al Bulushi, Maher Al Bahrani, Ibrahim Al-Zakwani
Summary: This study evaluated the demographic, clinical, laboratory, and all-cause mortality of moderate and severe COVID-19 patients admitted to a tertiary care hospital in Oman during the different COVID-19 waves and variant types.
Article
Medicine, Research & Experimental
Faryal Khamis, Salah Al Awaidy, Muna Al Shaaibi, Mubarak Al Shukeili, Shabnam Chhetri, Afra Al Balushi, Sumaiya Al Sulaimi, Amal Al Balushi, Ronald Wesonga
Summary: This study aimed to identify the epidemiological and clinical characteristics of hospitalized COVID-19 patients with moderate versus severe illness. The results showed that age, diabetes, and laboratory parameters had a significant impact on disease severity. The findings of this study can help prioritize and focus on key factors in assessing and managing COVID-19 patients.
Article
Public, Environmental & Occupational Health
Faryal Khamis, Abdallah Badahdah, Nawal Al Mahyijari, Furqan Al Lawati, Jaleela Al Noamani, Issa Al Salmi, Maher Al Bahrani
Summary: COVID-19 vaccine hesitancy is prevalent among healthcare workers in Oman, with physicians and male healthcare workers showing more positive attitudes towards the vaccines. Concerns about unknown health issues, efficacy, and safety were expressed by the participants.
JOURNAL OF EPIDEMIOLOGY AND GLOBAL HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Salah T. Al Awaidy, Faryal Khamis, Badria Al Rashidi, Ahmed H. Al Wahaibi, Abdulrahim Albahri, Ozayr Mahomed
Summary: The study in Oman showed that young Omani males had the highest incidence of COVID-19 infection and hospitalization, while mortality rates were higher among males and older age groups (>50 years). Identifying the epidemiological characteristics of COVID-19 patients is crucial for developing targeted intervention strategies and preparing for potential future waves of the pandemic.
JOURNAL OF EPIDEMIOLOGY AND GLOBAL HEALTH
(2021)
Article
Psychiatry
N. Al Mahyijari, A. Badahdah, F. Khamis
Summary: The COVID-19 pandemic has had harmful effects on the mental health of healthcare workers, with many experiencing high levels of stress and anxiety, as well as suboptimal levels of well-being.
IRISH JOURNAL OF PSYCHOLOGICAL MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
Faryal Khamis, Ziad Memish, Maher Al Bahrani, Hamed Al Nummani, Dana Al Raisi, Samata Al Dowaiki, Shabnam Chhetri, Fatma Al Fahdi, Maha Al Yahyai, Nenad Pandak, Zakariya Al Bolushi, Zainab Alarimi, Sabria Al Hashmi, Issa Al Salmi, Ibrahim Al-Zakwani
Summary: In patients with severe COVID-19 infection, treatment with tocilizumab and convalescent plasma is associated with improvement in inflammatory and ventilatory parameters, but does not impact mortality rate. These findings need further validation from randomized clinical trials.
JOURNAL OF EPIDEMIOLOGY AND GLOBAL HEALTH
(2021)
Article
Urology & Nephrology
Ali Almajrafi, Issa Al Salmi, Faryal Khamis, Nenad Pandak, Amina Al-Jardani, Eskild Petersen
Summary: West Nile virus (WNV) infections can lead to a variety of central nervous system diseases. Early diagnosis is crucial for immunosuppressed kidney transplant patients, and supportive treatment as well as appropriate immunomodulation may help control the disease.
SAUDI JOURNAL OF KIDNEY DISEASES AND TRANSPLANTATION
(2021)
Article
Psychiatry
Abdallah Badahdah, Faryal Khamis, Nawal Al Mahyijari, Marwa Al Balushi, Hashil Al Hatmi, Issa Al Salmi, Zakariya Albulushi, Jaleela Al Noomani
Summary: This study found a high prevalence of stress, anxiety, and poor psychological well-being among healthcare workers during the COVID-19 crisis, especially among females, young healthcare workers, and those who interacted with COVID-19 patients. The results highlight the urgency of providing administrative and psychological support, as well as current and accurate information on COVID-19 to healthcare workers.
INTERNATIONAL JOURNAL OF SOCIAL PSYCHIATRY
(2021)
