Article
Polymer Science
Jorge Ivan Castro, Carlos Humberto Valencia-Llano, Mayra Eliana Valencia Zapata, Yilmar Joan Restrepo, Jose Herminsul Mina Hernandez, Diana Paola Navia-Porras, Yamid Valencia, Cesar Valencia, Carlos David Grande-Tovar
Summary: The study synthesized four different film composites, with the addition of tea tree essential oil (TTEO) showing a reinforcement effect, exhibiting potential biocompatibility and signs of absorption after implantation experiment.
Article
Biochemistry & Molecular Biology
LeeAnn Nguyen, Brianna DeVico, Maliha Mannan, Matthew Chang, Cristina Rada Santacruz, Christopher Siragusa, Sydney Everhart, Christopher H. Fazen
Summary: Persister cells are a subset of bacteria that can survive antibiotic treatment and regrow after antibiotic removal, playing a key role in the reoccurrence of bacterial infections. Tea tree essential oil (TTO) has been found to completely eradicate persister cells of Escherichia coli and Staphylococcus epidermidis, primarily through the action of terpinen-4-ol, which disrupts the bacterial membrane.
Article
Materials Science, Multidisciplinary
Tiangao Jiang, Di Wang, Xueqin Zhang, Qian Yang, Qinfang Huang, Xianghong Ju, Lefan Li, Xinhuang Kang, Chengpeng Li
Summary: By utilizing the Pickering emulsion electrospinning strategy, tea tree oil with low solubility was successfully loaded into a hydrophilic nanofiber matrix, resulting in antimicrobial nanofibers with excellent blood compatibility and cell compatibility.
MATERIALS CHEMISTRY AND PHYSICS
(2024)
Article
Biochemistry & Molecular Biology
Hongpeng Yu, Qing Zhou, Dong He, Jinjin Yang, Kegang Wu, Xianghua Chai, Yujuan Xiang, Xuejuan Duan, Xiqin Wu
Summary: In this study, cinnamon essential oil and tea polyphenols were added to composite films to enhance their mechanical and functional properties. The addition of these additives improved the antibacterial and antioxidant properties of the films, as well as their transparency. The presence of the additives also led to the formation of a cross-linked structure in the films, improving their surface and cross-section morphology. The films with cinnamon essential oil exhibited enhanced thermal stability and storage quality indicators.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Food Science & Technology
Xueying Song, Lei Wang, Liu Liu, Jianke Li, Xiaoxia Wu
Summary: This study aimed to develop a novel antimicrobial packaging film using chitosan, deep eutectic solvent, and tea tree essential oil. The results showed that tea tree essential oil reduced the hydrophilicity of the film, while deep eutectic solvent significantly improved its flexibility. Micro-structural characterization revealed the interaction and uniform dispersion of the main components in the film. Antibacterial assays confirmed the antimicrobial activity of the film.
Article
Chemistry, Applied
Kepeng Hu, Erna Jia, Qimeng Zhang, Wei Zheng, Rongjiao Sun, Mengao Qian, Ying Tan, Wanle Hu
Summary: Tea tree oil (TTO) is encapsulated into the hydrogel network via a previous emulsification process, and a tough and antibacterial injectable hydrogel is synthesized by the Schiff base reaction between carboxymethyl chitosan (CMCS) and genipin (GP). The obtained hydrogels exhibit high adhesive strength (about 162.75 kPa), excellent antibacterial properties (over 90%), and great biocompatibility. The heterogeneous hydrogel shows good slow-release properties of TTO for accelerated healing of complex anal fistula wounds according to an anal fistula-like wound healing experiment.
CARBOHYDRATE POLYMERS
(2023)
Article
Polymer Science
Frederic Matussek, Adriana Pavinatto, Peggy Knospe, Sabine Beuermann, Rafaela Cristina Sanfelice
Summary: Chitosan-based polymeric films and droplets containing gold nanoparticles and tea tree oil were successfully prepared and studied for controlled release. The release time of tea tree oil was around 25 hours in the experiments. The effects of reaction temperature and acetic acid concentration on the formation of gold nanoparticles were also investigated.
Article
Biochemistry & Molecular Biology
Swarup Roy, Jong-Whan Rhim
Summary: A functional carrageenan/agar-based film was prepared by combining tea tree oil Pickering emulsion (PET) and zinc sulfide nanoparticles (ZnSNP). The incorporation of ZnSNPs improved the mechanical strength, while PET slightly decreased the strength. However, the combined addition of ZnSNP and PET maintained the mechanical strength with slightly improved flexibility, making it suitable for active food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Zhe Li, Xiaoxia Jiang, Hao Huang, Ao Liu, Hongning Liu, Naeem Abid, Liangshan Ming
Summary: The purpose of this study was to compare the properties of chitosan/zein edible films reinforced with Mosla chinensis essential oils nanoemulsions and nanoparticles. The results showed that films formulated with nanoemulsions exhibited excellent mechanical properties, moisture barrier capacity, and significant antioxidant and antibacterial activity. Moreover, nanoemulsion-based films improved the release of bioactive compounds.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Agricultural Engineering
Yirong Wang, Meng Cheng, Xiaoran Yan, Peixin Zhao, Kaiyue Wang, Yifan Wang, Xiangyou Wang, Juan Wang
Summary: In order to reduce environmental damage caused by non-degradable plastic packaging, environment-friendly active packaging films were developed using polyvinyl alcohol (PVA), sesbania gum (SG) as the film matrix, tea tree oil (TTO) as the active material, and hydroxyapatite porous microspheres (HPMS) as the loading system. The microcosmic appearance and structure of HPMS were analyzed through specific surface area and pore analysis, scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The addition of TTO-HPMS to the film matrix enhanced the thermal stability, antioxidant and antibacterial capacities of the packaging films, as well as improving their hydrophobicity. However, it also decreased the mechanical properties of the films, specifically the elongation at break (EB).
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Food Science & Technology
Meihong Cai, Gang Zhang, Jian Wang, Changzhu Li, Haiying Cui, Lin Lin
Summary: Encapsulating tea tree essential oil in nanoparticles and applying them to food packaging helps inhibit the growth of Salmonella typhimurium on meat surfaces, while also delaying oxidation. The use of nanofiber packaging effectively suppresses bacterial growth during storage without affecting the texture and color of the meat products.
Article
Biochemistry & Molecular Biology
Nourihan S. Farrag, Amro Shetta, Wael Mamdouh
Summary: The study focused on investigating the antineoplastic activity of green tea essential oil (GTO) as a natural product. Encapsulation of GTO in cationic chitosan nanoparticles (CS NPs) showed enhanced cytotoxic effect on cancer cell lines and successful complexation with technethium-99m (99mTc) radionuclide, highlighting the potential for anticancer therapy and diagnostic imaging.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Wendan Chen, Hua Liu, Yuhong Chai, Chenghu Guo, Chang Luo, Dongliang Chen, Xi Cheng, Fengjun Wang, Conglin Huang
Summary: Composite films were prepared using chitosan, pullulan, and Artemisia annua essential oil. The optimal amount of essential oil in the composite film was determined, resulting in improved mechanical properties and reduced water vapor transmission rate. The composite film exhibited high UV absorption and extended the storage time of grape berries, making it a promising fruit packaging material.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Lu Hua, Jieying Deng, Zhaoming Wang, Ying Wang, Bo Chen, Yunhao Ma, Xiaomin Li, Baocai Xu
Summary: The study aimed to obtain chitosan composite films with improved physical and functional properties by incorporating CEO-loaded C/ZN nanoparticles. The resulting films showed reduced water vapor permeability, increased tensile strength and break elongation, controlled-release properties, and enhanced antibacterial properties. Edible antibacterial films have great potential for applications in food preservation and delivery systems.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Physical
Sandra Flincec Grgac, Tea Tesla, Ivana Corak, Franka Zuvela Bosnjak
Summary: This study aimed to enhance the antimicrobial activity of chitosan by using tea tree essential oil to durably finish cotton fabrics for use in a hospital environment. The results showed the presence of a thin film on the surface of samples synthesized with tea tree essential oil and chitosan, indicating durability, as well as inhibition of bacteria and fungi.
Article
Chemistry, Applied
Maria Florez, Esther Guerra-Rodriguez, Patricia Cazon, Manuel Vazquez
Summary: The massive use of petroleum-based plastics in food packaging has led to serious environmental issues, prompting the need to develop biodegradable polymer packaging. Chitosan, a natural polysaccharide with non-toxic, antimicrobial, and antifungal properties, is considered a promising material for food packaging. Recent studies have evaluated the potential of active and/or intelligent chitosan-based films in improving food preservation and monitoring. The addition of active compounds has been shown to enhance the mechanical, barrier and functional properties of chitosan films, with potential applications in antimicrobial and antioxidant activities.
FOOD HYDROCOLLOIDS
(2022)
Article
Chemistry, Multidisciplinary
Patricia Cazon, Eduardo Morales-Sanchez, Gonzalo Velazquez, Manuel Vazquez
Summary: In recent years, there has been a significant shift in the food industry towards biodegradable packaging driven by social and environmental demands. This laboratory exercise aims to provide undergraduate students with a tool to actively learn about new technologies and trends in biopolymer chemistry. The focus of the exercise is on barrier properties, particularly water vapor permeability, using chitosan as an example. Detailed instructions are provided for the synthesis of chitosan and measurement of its water vapor permeability. Additionally, a 3D printing guide for a temperature-controlled permeability chamber is included to save time during the experiment. This exercise and the accompanying Supporting Information are expected to be valuable resources for biopolymer teaching and research laboratories.
JOURNAL OF CHEMICAL EDUCATION
(2022)
Article
Food Science & Technology
Patricia Cazon, Daniel Cazon, Manuel Vazquez, Esther Guerra-Rodriguez
Summary: The study found that UV-VIS-NIR spectroscopy combined with chemometric techniques can be used to authenticate the origin and determine the composition of polysaccharide-based films.
FOOD PACKAGING AND SHELF LIFE
(2022)
Article
Chemistry, Applied
Gema Puertas, Patricia Cazon, Manuel Vazquez
Summary: The aim of this study was to develop a quick and inexpensive method for detecting fraud in egg labels according to the four legally approved farming methods of the EU. Plasma obtained from egg centrifugation was investigated and evaluated for its protein content, color parameters, and UV-VIS-NIR spectra. The classification algorithms SVM, LDA, and QDA were utilized. The results showed that plasma spectral measurements combined with classification algorithms can be a powerful tool for discriminating the four farming systems.
Article
Food Science & Technology
Gema Puertas, Patricia Cazon, Manuel Vazquez
Summary: Membrane separation technology is widely used in research, food and pharmaceutical industries. This study assessed the application of UV-VIS-NIR spectroscopy in quantifying the composition of fractions obtained through membrane separation. The results showed that UV-VIS-NIR spectroscopy combined with chemometric tools is a reliable and efficient method for composition analysis in the membrane filtration process.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Pawel Rudnicki-Velasquez, Alicja Borylo, Marcin Kaczor, Jaroslaw Wieczorek, Jaroslawa Rutkowska
Summary: This study assessed the activity concentration and annual effective dose of Po-210 in fruit wines from different regions in Poland. The Po-210 activity in fruit wines varied significantly depending on the production site, with the highest activity in Malopolskie and the lowest in Podlaskie. The main factors contributing to the differentiation were environmental conditions such as soil parameters, precipitation, and proximity to lakes.
Article
Biotechnology & Applied Microbiology
Gema Puertas, Patricia Cazon, Manuel Vazquez
Summary: This study assessed the application of membrane separation technology to egg products. The interactions between egg yolk and egg white components made the separation difficult, but using modified polyethersulfone membrane for filtration could remove important nutrients such as cholesterol and carotenoids. Therefore, further research should evaluate the influence of cooking method and digestion on the bioaccessibility of nutrients and the generation of bioactive peptides from different egg components.
FOOD AND BIOPRODUCTS PROCESSING
(2023)
Review
Food Science & Technology
Braley Gentry, Patricia Cazon, Keely O'Brien
Summary: Described in detail that kefir grains are the natural starter for kefir production, which contains many yeast and bacterial species in a polysaccharide matrix called kefiran, with beneficial properties that make it a valuable biopolymer with widespread industrial applications. Various challenges in kefiran production, such as cost inefficiency and inhibition during fermentation, have hindered large-scale commercial production. This review focuses on the production, properties, and applications of kefiran in the food industry, pointing out the knowledge gaps and the need for further exploration.
INTERNATIONAL DAIRY JOURNAL
(2023)
Article
Polymer Science
Manuel Vazquez, Gema Puertas, Patricia Cazon
Summary: This study investigated the feasibility of using Garnacha Tintorera bagasse and potato wastes as substrates for the co-production of bacterial cellulose and gluconic acid. The results showed that the hydrolysis treatment improved the phenolic content of the bagasse extract and the addition of potato residues improved the glucose content of the culture medium. The fermentation experiments demonstrated that this method could achieve high yields of bacterial cellulose and gluconic acid.
Review
Polymer Science
Maria Florez, Patricia Cazon, Manuel Vazquez
Summary: Petroleum-based polymers are widely used in the commercial world, but their contamination and non-biodegradability make them unattractive. Biopolymers derived from nature offer an environmentally friendly alternative and reduce plastic waste. This review provides an overview of production methods for biopolymers, including the parameters affecting development, suitable biopolymers, and applications. Polymers derived from polysaccharides and proteins are the most studied, and their properties can be improved through production methods like solvent casting, coating, electrospinning, 3D printing, compression molding, and graft copolymerization. These biopolymers find applications in various fields such as biomedicine, pharmaceuticals, food packaging, and scaffold engineering.
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)