Review
Polymer Science
Maria de los Angeles Martinez Martinez, Lucia Soto Urzua, Yovani Aguilar Carrillo, Mirian Becerril Ramirez, Luis Javier Martinez Morales
Summary: In this review, the PHB production by A. brasilense is analyzed, including the carbon and nitrogen sources used, the synthesis and metabolic pathways of PHB, the role of genes involved in PHB metabolism, and the applications of PHB in the physiology of Azospirillum and biomedical and commercial areas.
Article
Engineering, Environmental
Jorge Luis Meraz, Anthony J. Abel, Douglas S. Clark, Craig S. Criddle
Summary: Bioconversion of methane into PHB offers a promising solution for methane management. This study develops a dynamic model that accurately predicts the growth and PHB accumulation of Type II methanotrophs. The model explores the impact of various factors on productivity and energy efficiency and identifies operational windows for optimizing PHB production.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Engineering, Environmental
P. R. Yashavanth, Meenakshi Das, Soumen K. Maiti
Summary: Plastic, while crucial in various sectors, poses severe environmental hazards due to its non-biodegradable nature. Eco-friendly bioplastics like PHB, produced from bacteria like cyanobacteria, show potential to replace conventional plastics. Challenges in industrial-scale PHB production still exist despite advancements in upstream and downstream processing strategies.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Biochemistry & Molecular Biology
Sun Mi Lee, Hong-Ju Lee, Sang Hyun Kim, Min Ju Suh, Jang Yeon Cho, Sion Ham, Hun-Suk Song, Shashi Kant Bhatia, Ranjit Gurav, Jong-Min Jeon, Jeong-Jun Yoon, Kwon-Young Choi, Jae-Seok Kim, Sang Ho Lee, Yung-Hun Yang
Summary: The engineered Shewanella marisflavi BBL25 can produce PHB by inserting polyhydroxyalkanoates synthesis genes from Ralstonia eutropha H16. High PHB production was achieved using barley straw hydrolysates as a carbon source. In addition, simultaneous production of PHB and electricity was demonstrated using the microbial fuel cell system.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Multidisciplinary
Piotr Jablonski, Dariush Nikjoo, Johan Warna, Knut Irgum, Jyri-Pekka Mikkola, Santosh Govind Khokarale
Summary: This report introduces a sustainable, metal-free, and single solvent-based reaction approach for the selective depolymerization of biopolymers to industrially valuable chemicals. The study investigates the influence of different reaction parameters on the conversion yield and efficiency.
Article
Biotechnology & Applied Microbiology
Meghna R. Malik, Nii Patterson, Nirmala Sharma, Jihong Tang, Claire Burkitt, Yuanyuan Ji, Matthew Martino, Andrew Hertig, Dirk Schweitzer, Oliver Peoples, Kristi D. Snell
Summary: Plant-based production of polyhydroxyalkanoates (PHAs) and seed oil can provide a sustainable source of feedstocks for renewable fuels and plastics. This study successfully engineered Camelina sativa to produce PHA poly[(R)-3-hydroxybutyrate] (PHB) in the seed cytosol using a bacterial PHB biosynthetic pathway. By localizing the key enzymes to the cytosol and endoplasmic reticulum, stable polymer production was achieved with PHB levels reaching 10.2% of seed weight. This research represents a significant advancement towards commercial use of plant-based PHAs, connecting large-scale agricultural production with the plastics and renewable fuels markets.
PLANT BIOTECHNOLOGY JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
Mohammad Mohammadalipour, Saeed Karbasi, Tayebeh Behzad, Zahra Mohammadalipour, Maryam Zamani
Summary: The choice of materials and preparation methods are crucial for the characteristics of scaffolds. In this study, cellulose nanofibers were used as nano-additives to prepare a polyhydroxybutyrate (PHB) based nanocomposite scaffold. The properties of the PHB/CNF scaffold were compared with pure PHB, and the results showed improvements in crystallinity, water contact angle, degradation rate, biomineralization, toughness factor, and surface roughness. Moreover, the PC nanocomposite demonstrated better cell viability and spreading, indicating its potential in bone tissue engineering.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Biotechnology & Applied Microbiology
Daiana Trape, Olivia Lopez, Marcelo A. Villar
Summary: This study aimed to produce PHB from vinasse by Bacillus megaterium, finding that higher C or N concentrations led to decreased productivity. Optimization was conducted and it was concluded that biopolymer production from vinasse is a feasible alternative.
BIORESOURCES AND BIOPROCESSING
(2021)
Article
Chemistry, Applied
Seo A. Park, Kwon-Young Choi
Summary: Indigo derivatives incorporating Poly(3-hydroxybutyrate) (IDPs) were produced in a single recombinant Escherichia coli strain through a one-pot process. The IDPs were analyzed for various biological and physical properties, revealing that 5-OH IDP exhibited higher thermal stability, while 4-NO2 IDP showed the lowest resistance to biodegradation.
Article
Biochemistry & Molecular Biology
Mohammad Mohammadalipour, Tayebeh Behzad, Saeed Karbasi, Zahra Mohammadalipour
Summary: This study investigates the optimization of electrospinning process conditions and the addition of lignin to improve the performance of polyhydroxybutyrate (PHB) scaffolds. The results show that the addition of lignin can reduce the brittleness and hydrophobicity of PHB, improve the uniformity of electrospun nanofibers, and enhance the mechanical properties of PHB. Moreover, the PHB/lignin electrospun scaffold exhibits potential for promoting cell growth and mineralization, as well as antioxidant activity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Green & Sustainable Science & Technology
Demetres Briassoulis, Philippos Tserotas, Ioanna-Georgia Athanasoulia
Summary: Polyhydroxyalkanoates (PHAs), a group of bio-based polymeric materials formed by microorganisms, include the well-known member Poly(3-hydroxybutyrate) (PHB). Despite PHB's high biodegradability and biocompatibility, its low ductility and susceptibility to thermal degradation limit its applications. Alternative strategies such as modification and blending are needed to enhance the performance of PHB for producing bio-based plastics with improved properties.
JOURNAL OF CLEANER PRODUCTION
(2021)
Article
Multidisciplinary Sciences
Doeun Jeon, Lingmin Jiang, Ki-Hyun Kim, Yuxin Peng, Donghyun Cho, Rae-Dong Jeong, Cha Young Kim, Jae Cheol Jeong, Jiyoung Lee
Summary: A new rod-shaped bacterium strain DM-R-R2A-13(T), named Massilia endophytica sp. nov., was isolated from the plant Cannabis sativa L. 'Cheungsam'. The strain has the potential to produce the bioplastic poly-3-hydroxybutyrate (PHB).
SCIENTIFIC REPORTS
(2023)
Article
Biotechnology & Applied Microbiology
Lionel F. Longe, Laurent Michely, Antoine Gallos, Agustin Rios De Anda, Henri Vahabi, Estelle Renard, Michel Latroche, Florent Allais, Valerie Langlois
Summary: This study used three novel additives based on ferulic acid esterified with different alcohols to improve the mechanical properties of poly(3-hydroxybutyrate) (PHB). The additive BDF significantly increased the processing window and elongation at break of PHB. The highly thermally stable additive also enhanced the fire-retardant property of the material and exhibited antioxidant properties.
BIOENGINEERING-BASEL
(2022)
Article
Biochemistry & Molecular Biology
Saeid Ghasemi, Afshin Alibabaie, Reyhane Saberi, Mahdie Esmaeili, Dariush Semnani, Saeed Karbasi
Summary: This study blended zein with polyhydroxybutyrate (PHB) to fabricate scaffolds and characterized their properties. The optimal sample was found to be the scaffold with 10% zein (PHB-10Z), which showed improved mechanical properties and surface roughness compared to pure PHB. The presence of zein in the scaffold was confirmed, and the PHB-10Z scaffold exhibited antioxidant activity and enhanced cell attachment and differentiation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Mohammad Mohammadalipour, Mehrdad Asadolahi, Zahra Mohammadalipour, Tayebeh Behzad, Saeed Karbasi
Summary: Polyhydroxybutyrate (PHB) nanofibers were prepared by electrospinning and their surface was modified by atmospheric plasma. The modified nanofibers showed lower water contact angle, appropriate degradation rate, and outstanding biomineralization compared to the untreated samples. Cell behavior analyses also demonstrated better cell proliferation with the modified mats in bone tissue engineering. These findings support the use of plasma surface modification as a quick, environmentally friendly, and low-cost approach to enhance the performance of nanofibers.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Energy & Fuels
Prangya Ranjan Rout, Mukesh Goel, Anee Mohanty, Daya Shankar Pandey, Nirmalya Halder, Sanjay Mukherjee, Shashi Kant Bhatia, Naresh Kumar Sahoo, Sunita Varjani
Summary: This review highlights the valorisation of wastewater during hydrothermal liquefaction (HTL) of biomass, focusing on the role of microalgae in wastewater utilization. The study findings suggest that the selection of appropriate technology is dependent on the characteristics of the microalgae. Recommendations for potential research opportunities are provided to improve the viability of HTL wastewater valorisation.
BIOENERGY RESEARCH
(2023)
Article
Green & Sustainable Science & Technology
A. E. Atabani, Eyas Mahmoud, Muhammed Aslam, Salman Raza Naqvi, Dagmar Juchelkova, Shashi Kant Bhatia, Irfan Anjum Badruddin, T. M. Yunus Khan, Anh Tuan Hoang, Petr Palacky
Summary: The global market for fuel pellets is growing due to coal substitutes, but sustainability and biomass availability are major issues. Spent coffee grounds can be used to produce high heating value fuel pellets, but burning 100% SCG leads to high NO R emissions and low boiler efficiency. Mixing SCG with other biomass improves combustion performance. Further research is needed on the combustion and emissions of defatted spent coffee grounds.
ENVIRONMENT DEVELOPMENT AND SUSTAINABILITY
(2023)
Article
Chemistry, Physical
Chayanika Putatunda, Manya Behl, Preeti Solanki, Samriti Sharma, Shashi Kant Bhatia, Abhishek Walia, Ravi Kant Bhatia
Summary: Biohydrogen is considered a versatile future fuel that can replace fossil fuels in various sectors, and photofermentation is an attractive approach due to its efficiency and reduced environmental impacts. However, there are still significant challenges in commercial biohydrogen production through photofermentation. This review provides updated information on new technologies and discusses the prospects for the future of green biohydrogen production.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2023)
Article
Agricultural Engineering
Jeyaprakash Dharmaraja, Sutha Shobana, Sundaram Arvindnarayan, Rusal Raj Francis, Rajesh Banu Jeyakumar, Rijuta Ganesh Saratale, Veeramuthu Ashokkumar, Shashi Kant Bhatia, Vinod Kumar, Gopalakrishnan Kumar
Summary: During the pretreatment of lignocellulose biomass, reducing sugars are released and can be used for the production of biofuels and other products. Innovative greener pretreatment techniques are being considered to improve the digestibility of lignocellulosic materials and remove hemicellulose/lignin to yield valid bioproducts.
BIORESOURCE TECHNOLOGY
(2023)
Article
Agricultural Engineering
Shashi Kant Bhatia, Ranjit Gurav, Do-Hyun Cho, Byungchan Kim, Hee Ju Jung, Su Hyun Kim, Tae -Rim Choi, Hyun-Joong Kim, Yung -Hun Yang
Summary: In this study, fourteen types of biochar produced from seven different biomasses at 300 degrees C and 600 degrees C were tested for their ability to remove phenolics including furfural and hydroxymethylfurfural (HMF). Eucheuma spinosum biochar (EB-BC 600) showed the highest adsorption capacity for furfural (258.94 +/- 3.2 mg/g) and HMF (222.81 +/- 2.3 mg/g). Detoxified hydrolysates using EB-BC 600 biochar resulted in significantly increased production of polyhydroxyalkanoates (PHA).
BIORESOURCE TECHNOLOGY
(2023)
Review
Agricultural Engineering
Nitin Kumar Singh, Manish Yadav, Vijai Singh, Hirendrasinh Padhiyar, Vinod Kumar, Shashi Kant Bhatia, Pau-Loke Show
Summary: Artificial intelligence (AI) and machine learning (ML) are currently being used in multiple domains, including the monitoring and design of biological wastewater treatment systems (WWTS). This paper reviews the available information on the applications of AI and ML models in WWTS, presenting bibliometric analyses, model descriptions, specific applications, and major findings. Predominantly used models in biological wastewater treatment include artificial neural networks (ANN), fuzzy logic (FL) algorithms, random forest (RF), and long short-term memory (LSTM), which are tested for predictive control of effluent parameters such as biological oxygen demand (BOD), chemical oxygen demand (COD), nutrient parameters, solids, and metallic substances. Commonly used model performance indicators for accuracy analysis include root mean squared error (RMSE), mean square error (MSE), and determination coefficient (DC). Additionally, this study summarizes the outcomes of various models.
BIORESOURCE TECHNOLOGY
(2023)
Article
Engineering, Environmental
Jiyeong Jeong, Tae Hyun Kim, Nulee Jang, Minji Ko, Seong Keun Kim, Georgii Emelianov, Eugene Rha, Kil Koang Kwon, Haseong Kim, Eun Yeol Lee, Dae-Hee Lee, Hyewon Lee, Seung-Goo Lee
Summary: Methanotrophs have been successfully engineered to produce valuable bioproducts from methane by utilizing a phenol-inducible gene expression system and a CRISPR-based genome editing tool. The engineered strain achieved the highest concentration of synthetic biochemicals produced from methane in methanotrophs.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
Hong-Ju Lee, Hee Ju Jung, Byungchan Kim, Do-Hyun Cho, Su Hyun Kim, Shashi Kant Bhatia, Ranjit Gurav, Yun-Gon Kim, Sang-Won Jung, Hyun June Park, Yung-Hun Yang
Summary: This study aims to investigate the effect of heterologous phasins on the production of polyhydroxybutyrate (PHB) in E. coli and determine the best combination of phaP genes. By introducing a combination of phaP genes from a high-producing strain, Halomonas sp. YLGW01, into E. coli, the resulting strain showed a 2.9-fold increase in PHB production, with increased cell mass and PHB content reaching 65%. This strain also exhibited increased tolerance to inhibitors and could utilize lignocellulosic biomass as a carbon source.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Biotechnology & Applied Microbiology
Ushasree Mrudulakumari Vasudevan, Dung Hoang Anh Mai, Shyam Krishna, Eun Yeol Lee
Summary: Methanotrophs have the potential to produce various bioactive secondary metabolites including iso-prenoids, polymers, peptides, and vitamins. Genome mining of these microbes revealed the hidden biosynthetic potential of these microbes. Through advanced synthetic biology tools, the central carbon metabolism in methanotrophs can be modified to produce valuable secondary metabolites. This review summarizes the possibilities of developing methanotrophs as microbial chassis for high-value secondary metabolites.
BIOTECHNOLOGY ADVANCES
(2023)
Review
Chemistry, Multidisciplinary
My Ha Tran, Eun Yeol Lee
Summary: This article reviews the methods for producing polyols from vegetable oil, lignin, and carbohydrates, as well as the production of polyurethane from biomass polyols. Conversion of vegetable oil involves epoxidation, hydroformylation, and transesterification, while conversion of lignin involves solvothermal liquefaction, hydroxymethylation, oxypropylation, and phenolation.
ENVIRONMENTAL CHEMISTRY LETTERS
(2023)
Article
Multidisciplinary Sciences
Sanzhar Naizabekov, Seung Woon Hyun, Jeong-Geol Na, Sukhwan Yoon, Ok Kyung Lee, Eun Yeol Lee
Summary: Comparative genomic analysis revealed the potential of newly isolated methanotroph Methylocystis sp. MJC1 as a biodegradable polyhydroxybutyrate (PHB) producer. Under nitrogen-limiting conditions, Methylocystis sp. MJC1 can accumulate up to 44.5% PHB based on dry cell weight. Functional annotation and comparison with other Methylocystis species showed that Methylocystis sp. MJC1 contains all major biochemical pathways of type II methanotrophs and possesses both particulate and soluble methane monooxygenases, which are not commonly found in other Methylocystis species. These findings open up possibilities for future practical applications such as organism-specific genome-scale models and metabolic engineering strategies.
Review
Polymer Science
Vishal Ahuja, Arvind Kumar Bhatt, J. Rajesh Banu, Vinod Kumar, Gopalakrishnan Kumar, Yung-Hun Yang, Shashi Kant Bhatia
Summary: Microbial exopolysaccharides (EPSs) such as xanthan, dextran, gellan, and curdlan have various applications in industries due to their biocompatibility, nontoxicity, and functional characteristics. However, their commercial use in healthcare practices is hindered by biodegradability issues, poor cell adhesion, mineralization, and low enzyme activity. Blending EPSs with other polymers can improve their characteristics and make the composites suitable for diverse applications, especially tissue engineering. More research is needed to address the challenges and commercialize these products.
Editorial Material
Polymer Science
Shashi Kant Bhatia
Article
Chemistry, Multidisciplinary
Dieu-Phuong Phan, My Ha Tran, Eun Yeol Lee
Summary: Polymeric materials play a crucial role in modern society, and biomass can be utilized as a renewable carbon source for the production of bio-based plastics. This review summarizes the applications of Metal-Organic Framework (MOF)-based catalysts in the production of renewable bio-plastic-derived materials and highlights the effects of reaction conditions.
MATERIALS TODAY CHEMISTRY
(2023)
Review
Environmental Sciences
Sonika Kumari, Varruchi Sharma, Savita Soni, Ajay Sharma, Abhinay Thakur, Satish Kumar, Kuldeep Dhama, Anil Kumar Sharma, Shashi Kant Bhatia
Summary: Layered double hydroxides (LDHs) are a class of materials with unique structures and properties that have a wide range of applications. LDHs can be synthesized in a cost-effective and environmentally friendly manner through aqueous synthetic pathways, and they have the advantages of easy modification and controlled release. LDHs have great potential in drug delivery, as they can stabilize drugs, enhance solubility, and control release. Additionally, LDHs have good biocompatibility and cellular uptake. This study demonstrates the applications of LDHs and their hybrids/composites in drug, cosmeceutical, and gene delivery systems.
ENVIRONMENTAL RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
