Heerfordt's Syndrome Associated with Trigeminal Nerve Palsy and Reversed Halo Sign

Heerfordt's syndrome is a rare subtype of sarcoidosis and features a combination of facial palsy, parotid swelling, and uveitis, associated with a low-grade fever. Cases with two of three symptoms are called incomplete Heerfordt's syndrome. Heerfordt's syndrome involving other cranial nerve symptoms is relatively rare. We herein report a case of incomplete Heerfordt's syndrome presenting with trigeminal nerve palsy and a reversed halo sign, a rare manifestation of pulmonary sarcoidosis. The histological diagnosis following a biopsy of the parotid gland and endobronchial ultrasound-guided trans-bronchial needle aspiration of the mediastinal lymph nodes was sarcoidosis. The symptoms and lung lesions improved after corticosteroid therapy.

Automated summary

Heerfordt's syndrome is a rare subtype of sarcoidosis characterized by facial palsy, parotid swelling, and uveitis. This study presents a case of incomplete Heerfordt's syndrome with trigeminal nerve palsy and a reversed halo sign, showing improvement after corticosteroid therapy.