Journal
FITOTERAPIA
Volume 113, Issue -, Pages 182-187Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2016.07.015
Keywords
Agarwood; Gyrinops salicifolia; Sesquiterpenes; AChE inhibitory activities
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Funding
- Special Fund for Agro-scientific Research in the Public Interest [201303117]
- Natural Science Fund of Hainan Province [20168367]
- Special Fund for The Young Talents's Science and Technology Project of Hainan Association for Science and Technology [HASI201628]
- Special Fund for Key Research Project of Hainan Province [ZDYF2016210]
- Major Technology Project of Hainan Province [ZDKJ2016004-03]
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Six new sesquiterpenoids (1-6) and six known sesquiterpenoids (7-12) were isolated from agarwood originated from Gyrinops salicifolia Ridl. Most of them gave off aromatic odor, and all the compounds were isolated from this genus for the first time. The structures of 1-6 were elucidated by spectroscopic techniques (UV, IR, 1D and 2D NMR) and MS analysis, as well as by comparison with literature data. Compounds 1, 6 and 11-12 showed moderate acetylcholinesterase (AChE) inhibitory activity. (C) 2016 Published by Elsevier B.V.
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