Chlamydia Spreads to the Large Intestine Lumen via Multiple Pathways

Chlamydia overcomes multiple gastrointestinal barriers to achieve long-lasting colonization

(2021) Guangming Zhong   TRENDS IN MICROBIOLOGY

Gastrointestinal co-infection promotes chlamydial pathogenicity in the genital tract

(2020) Qi Tian et al.   INFECTION AND IMMUNITY

Effects of Immunomodulatory Drug Fingolimod (FTY720) on Chlamydia Dissemination and Pathogenesis

(2020) Zengzi Zhou et al.   INFECTION AND IMMUNITY

The plasmid-encoded pGP3 promotes Chlamydia evasion of acidic barriers in both stomach and vagina

(2019) Tianyuan Zhang et al.   INFECTION AND IMMUNITY

Antigen-Specific CD4+ T Cell-Derived Gamma Interferon Is Both Necessary and Sufficient for Clearing Chlamydia from the Small Intestine but Not the Large Intestine

(2019) Hui Lin et al.   INFECTION AND IMMUNITY

Dissemination of Chlamydia from the reproductive tract to the gastro-intestinal tract occurs in stages and relies on Chlamydia transport by host cells

(2019) Savannah E. Howe et al.   PLoS Pathogens

Chlamydia Spreading from the Genital Tract to the Gastrointestinal Tract – A Two-Hit Hypothesis

(2018) Guangming Zhong   TRENDS IN MICROBIOLOGY

IL-6-mediated signaling pathways limit Chlamydia muridarum infection and exacerbate its pathogenicity in the mouse genital tract

(2017) Xin Sun et al.   MICROBES AND INFECTION

Chlamydial Plasmid-Dependent Pathogenicity

(2017) Guangming Zhong   TRENDS IN MICROBIOLOGY

Recent advances and future directions in understanding and treating Chlamydia-induced reactive arthritis

(2016) John D. Carter et al.   Expert Review of Clinical Immunology

Intravenous Inoculation with Chlamydia muridarum Leads to a Long-Lasting Infection Restricted to the Gastrointestinal Tract

(2016) Jin Dai et al.   INFECTION AND IMMUNITY

The Chlamydia muridarum Organisms Fail to Auto-Inoculate the Mouse Genital Tract after Colonization in the Gastrointestinal Tract for 70 days

(2016) Luying Wang et al.   PLoS One

Is it time to switch to doxycycline from azithromycin for treating genital chlamydial infections in women? Modelling the impact of autoinoculation from the gastrointestinal tract to the genital tract

(2015) Andrew P Craig et al.   BMC INFECTIOUS DISEASES

The Chromosome-Encoded Hypothetical Protein TC0668 Is an Upper Genital Tract Pathogenicity Factor of Chlamydia muridarum

(2015) Turner Allen Conrad et al.   INFECTION AND IMMUNITY

In VitroPassage Selects for Chlamydia muridarum with Enhanced Infectivity in Cultured Cells but Attenuated Pathogenicity in Mouse Upper Genital Tract

(2015) Chaoqun Chen et al.   INFECTION AND IMMUNITY

In VivoandEx VivoImaging Reveals a Long-Lasting Chlamydial Infection in the Mouse Gastrointestinal Tract following Genital Tract Inoculation

(2015) Qi Zhang et al.   INFECTION AND IMMUNITY

Rectal chlamydia infection in women at high risk of chlamydia attending Canberra Sexual Health Centre

(2015) Kate Musil et al.   INTERNATIONAL JOURNAL OF STD & AIDS

Evidence for Increased Chlamydia Case Finding After the Introduction of Rectal Screening Among Women Attending 2 Canadian Sexually Transmitted Infection Clinics

(2014) J. Gratrix et al.   CLINICAL INFECTIOUS DISEASES

Complement Factor C5 but Not C3 Contributes Significantly to Hydrosalpinx Development in Mice Infected with Chlamydia muridarum

(2014) Zhangsheng Yang et al.   INFECTION AND IMMUNITY

Plasmid-Encoded Pgp3 Is a Major Virulence Factor for Chlamydia muridarum To Induce Hydrosalpinx in Mice

(2014) Yuanjun Liu et al.   INFECTION AND IMMUNITY

Chlamydial Induction of Hydrosalpinx in 11 Strains of Mice Reveals Multiple Host Mechanisms for Preventing Upper Genital Tract Pathology

(2014) Jianlin Chen et al.   PLoS One

Bioluminescence Imaging of Chlamydia muridarum Ascending Infection in Mice

(2014) Jessica Campbell et al.   PLoS One

Prevalence and Characteristics of Rectal Chlamydia and Gonorrhea Cases Among Men Who Have Sex With Men After the Introduction of Nucleic Acid Amplification Test Screening at 2 Canadian Sexually Transmitted Infection Clinics

(2014) Jennifer Gratrix et al.   SEXUALLY TRANSMITTED DISEASES

Cross-Sectional Study of Genital, Rectal, and Pharyngeal Chlamydia and Gonorrhea in Women in Rural South Africa

(2014) Remco P.H. Peters et al.   SEXUALLY TRANSMITTED DISEASES

Human enteroendocrine cell responses to infection with Chlamydia trachomatis: a microarray study

(2014) Aldona Dlugosz et al.   Gut Pathogens

Reduced Live Organism Recovery and Lack of Hydrosalpinx in Mice Infected with Plasmid-Free Chlamydia muridarum

(2013) Lei Lei et al.   INFECTION AND IMMUNITY

Prevention of Chlamydia-Induced Infertility by Inhibition of Local Caspase Activity

(2013) Joseph U. Igietseme et al.   JOURNAL OF INFECTIOUS DISEASES

Oviduct Infection and Hydrosalpinx in DBA1/j Mice Is Induced by Intracervical but Not Intravaginal Inoculation with Chlamydia muridarum

(2013) Lingli Tang et al.   PLoS One

B Cells Enhance Antigen-Specific CD4 T Cell Priming and Prevent Bacteria Dissemination following Chlamydia muridarum Genital Tract Infection

(2013) Lin-Xi Li et al.   PLoS Pathogens

Chlamydial infection of the gastrointestinal tract: a reservoir for persistent infection

(2013) Laxmi Yeruva et al.   Pathogens and Disease

Chlamydia trachomatis Antigens Recognized in Women With Tubal Factor Infertility, Normal Fertility, and Acute Infection

(2012) Nicole M. Budrys et al.   OBSTETRICS AND GYNECOLOGY

Genome-wide identification of Chlamydia trachomatis antigens associated with tubal factor infertility

(2011) Allison K. Rodgers et al.   FERTILITY AND STERILITY

Retro-orbital injections in mice

(2011) Tal Yardeni et al.   LAB ANIMAL

Vaccination with the defined chlamydial secreted protein CPAF induces robust protection against female infertility following repeated genital chlamydial challenge

(2011) Ashlesh K. Murthy et al.   VACCINE

Association of tubal factor infertility with elevated antibodies to Chlamydia trachomatis caseinolytic protease P

(2010) Allison K. Rodgers et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Bacterial Entry to the Splenic White Pulp Initiates Antigen Presentation to CD8+ T Cells

(2008) Taiki Aoshi et al.   IMMUNITY