Efficacy and safety of apararenone (MT‐3995) in patients with nonalcoholic steatohepatitis: A randomized controlled study

Frequently abnormal serum gamma-glutamyl transferase activity is associated with future development of fatty liver: a retrospective cohort study

(2020) Hideki Fujii et al.   BMC GASTROENTEROLOGY

Apararenone in patients with diabetic nephropathy: results of a randomized, double-blind, placebo-controlled phase 2 dose–response study and open-label extension study

(2020) Takashi Wada et al.   Clinical and Experimental Nephrology

Phase 1 Studies to Define the Safety, Tolerability, and Pharmacokinetic and Pharmacodynamic Profiles of the Nonsteroidal Mineralocorticoid Receptor Antagonist Apararenone in Healthy Volunteers

(2020) Tadakatsu Nakamura et al.   Clinical Pharmacology in Drug Development

Non-Invasive Assessment of Liver Disease in Patients with NAFLD

(2019) Laurent Castera et al.   GASTROENTEROLOGY

Report on the AASLD/EASL joint workshop on clinical trial endpoints in NAFLD

(2019) Mary E. Rinella et al.   JOURNAL OF HEPATOLOGY

Appraising diagnostic performance of ELF test by pathological staging and digital quantification of liver fibrosis

(2019) Ender Gunes Yegin et al.   Annals of Hepatology

Multi-drug approaches to NASH: what’s in the development pipeline?

(2019) Michael P Johnston et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers

(2018) Takahisa Kawaguchi et al.   PLoS One

A simple scoring system using type IV collagen 7S and aspartate aminotransferase for diagnosing nonalcoholic steatohepatitis and related fibrosis

(2017) Takeshi Okanoue et al.   JOURNAL OF GASTROENTEROLOGY

EASL–EASD–EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease

(2016) et al.   DIABETOLOGIA

Relationships between Genetic Variations of PNPLA3, TM6SF2 and Histological Features of Nonalcoholic Fatty Liver Disease in Japan

(2016) Norio Akuta et al.   Gut and Liver

Classification of patients with non-alcoholic fatty liver disease using rapid immunoassay of serum type IV collagen compared with liver histology and other fibrosis markers

(2016) Masayuki Mizuno et al.   HEPATOLOGY RESEARCH

Biomarkers in Nonalcoholic Fatty Liver Disease

(2016) Manuela G Neuman et al.   Canadian Journal of Gastroenterology and Hepatology

Weight Loss Through Lifestyle Modification Significantly Reduces Features of Nonalcoholic Steatohepatitis

(2015) Eduardo Vilar-Gomez et al.   GASTROENTEROLOGY

Beneficial effects of mineralocorticoid receptor blockade in experimental non-alcoholic steatohepatitis

(2015) Margarita Pizarro et al.   LIVER INTERNATIONAL

Are oxidative stress mechanisms the common denominator in the progression from hepatic steatosis towards non-alcoholic steatohepatitis (NASH)?

(2014) Zoon Tariq et al.   LIVER INTERNATIONAL

Eplerenone ameliorates the phenotypes of metabolic syndrome with NASH in liver-specific SREBP-1c Tg mice fed high-fat and high-fructose diet

(2013) Tsutomu Wada et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Enhanced Liver Fibrosis (ELF) score: Normal values, influence factors and proposed cut-off values

(2013) Ralf Lichtinghagen et al.   JOURNAL OF HEPATOLOGY

Validation of terminal peptide of procollagen III for the detection and assessment of nonalcoholic steatohepatitis in patients with nonalcoholic fatty liver disease

(2012) Sudeep Tanwar et al.   HEPATOLOGY

Prevalence and associated metabolic factors of nonalcoholic fatty liver disease in the general population from 2009 to 2010 in Japan: a multicenter large retrospective study

(2012) Yuichiro Eguchi et al.   JOURNAL OF GASTROENTEROLOGY

Non-invasive diagnosis of non-alcoholic fatty liver disease. A critical appraisal

(2012) Mariana V. Machado et al.   JOURNAL OF HEPATOLOGY

Genetic Polymorphisms of the Human PNPLA3 Gene Are Strongly Associated with Severity of Non-Alcoholic Fatty Liver Disease in Japanese

(2012) Takahisa Kawaguchi et al.   PLoS One

Histopathological stages of nonalcoholic fatty liver disease in type 2 diabetes: prevalences and correlated factors

(2011) Nathalie C. Leite et al.   LIVER INTERNATIONAL

Clinical features and outcomes of cirrhosis due to non-alcoholic steatohepatitis compared with cirrhosis caused by chronic hepatitis C

(2008) Satoru Yatsuji et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY