Deregulation of mitochondrial sirtuins and OGG1-2a acts as a prognostic and diagnostic biomarker in leukemia

Dual Tumor Suppressor and Tumor Promoter Action of Sirtuins in Determining Malignant Phenotype

(2019) Vincenzo Carafa et al.   Frontiers in Pharmacology

Expression deregulation of DNA repair pathway genes in gastric cancer

(2019) Shahzad Yousaf et al.   Cancer Genetics

Sirtuin-4 (SIRT4), a therapeutic target with oncogenic and tumor-suppressive activity in cancer

(2018) Guoyu Huang et al.   OncoTargets and Therapy

Role of NAD+ and mitochondrial sirtuins in cardiac and renal diseases

(2017) Kathleen A. Hershberger et al.   Nature Reviews Nephrology

Down-regulation of SIRT3 promotes ovarian carcinoma metastasis

(2016) Xue-cai Dong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

High-throughput screening of Sirtuin family of genes in breast cancer

(2016) Mehri Igci et al.   GENE

Decreased sirtuin 4 expression is associated with poor prognosis in patients with invasive breast cancer

(2016) Qingyu Shi et al.   Oncology Letters

Loss of Mitochondrial Tumor Suppressor Genes Expression Is Associated with Unfavorable Clinical Outcome in Head and Neck Squamous Cell Carcinoma: Data from Retrospective Study

(2016) Ishrat Mahjabeen et al.   PLoS One

Assessing sirtuin expression in endometrial carcinoma and non-neoplastic endometrium

(2015) Carla Bartosch et al.   Oncotarget

SIRT5 facilitates cancer cell growth and drug resistance in non-small cell lung cancer

(2014) Weidong Lu et al.   TUMOR BIOLOGY

SIRT5 desuccinylates and activates SOD1 to eliminate ROS

(2013) Zhi-Feng Lin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Aberrant expression of SIRT3 is conversely correlated with the progression and prognosis of human gastric cancer

(2013) Bing Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SIRT4 Has Tumor-Suppressive Activity and Regulates the Cellular Metabolic Response to DNA Damage by Inhibiting Mitochondrial Glutamine Metabolism

(2013) Seung Min Jeong et al.   CANCER CELL

The mTORC1 Pathway Stimulates Glutamine Metabolism and Cell Proliferation by Repressing SIRT4

(2013) Alfred Csibi et al.   CELL

SIRT4 Represses Peroxisome Proliferator-Activated Receptor α Activity To Suppress Hepatic Fat Oxidation

(2013) Gaëlle Laurent et al.   MOLECULAR AND CELLULAR BIOLOGY

SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways

(2013) Jeongsoon Park et al.   MOLECULAR CELL

Decreased mitochondrial OGG1 expression is linked to mitochondrial defects and delayed hepatoma cell growth

(2013) Young-Kyoung Lee et al.   MOLECULES AND CELLS

Mitochondria in metabolic disease: Getting clues from proteomic studies

(2013) Juan R. Peinado et al.   PROTEOMICS

Altered expression of SIRT gene family in head and neck squamous cell carcinoma

(2013) Chi-Chih Lai et al.   TUMOR BIOLOGY

Interaction of Sirt3 with OGG1 contributes to repair of mitochondrial DNA and protects from apoptotic cell death under oxidative stress

(2013) Y Cheng et al.   Cell Death & Disease

Sirt3 inhibits hepatocellular carcinoma cell growth through reducing Mdm2-mediated p53 degradation

(2012) Yuan-Yuan Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Histone Deacetylase Inhibitors Demonstrate Significant Preclinical Activity as Single Agents, and in Combination with Bortezomib in Waldenström's Macroglobulinemia

(2012) Jenny Y. Sun et al.   Clinical Lymphoma Myeloma & Leukemia

SIRT5 deacetylates and activates urate oxidase in liver mitochondria of mice

(2012) Yasuhiko Nakamura et al.   FEBS LETTERS

Decreased mRNA expression levels of base excision repair (BER) pathway genes is associated with enhanced Ki-67 expression in HNSCC

(2012) Ishrat Mahjabeen et al.   MEDICAL ONCOLOGY

Lysine Succinylation and Lysine Malonylation in Histones

(2012) Zhongyu Xie et al.   MOLECULAR & CELLULAR PROTEOMICS

Sirt5 Is a NAD-Dependent Protein Lysine Demalonylase and Desuccinylase

(2011) J. Du et al.   SCIENCE

SIRT4 Regulates Fatty Acid Oxidation and Mitochondrial Gene Expression in Liver and Muscle Cells

(2010) Nargis Nasrin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Upregulated INHBA expression is associated with poor survival in gastric cancer

(2010) Quan Wang et al.   MEDICAL ONCOLOGY

Identification of lysine succinylation as a new post-translational modification

(2010) Zhihong Zhang et al.   Nature Chemical Biology

SIRT5 Deacetylates Carbamoyl Phosphate Synthetase 1 and Regulates the Urea Cycle

(2009) Takashi Nakagawa et al.   CELL

Recent progress in the biology and physiology of sirtuins

(2009) Toren Finkel et al.   NATURE

OGG1 is a novel prognostic indicator in acute myeloid leukaemia

(2009) K Liddiard et al.   ONCOGENE