Hypoxia inhibits RANKL-induced ferritinophagy and protects osteoclasts from ferroptosis

Energy-stress-mediated AMPK activation inhibits ferroptosis

(2020) Hyemin Lee et al.   NATURE CELL BIOLOGY

Loss of Cardiac Ferritin H Facilitates Cardiomyopathy via Slc7a11-Mediated Ferroptosis

(2020) Xuexian Fang et al.   CIRCULATION RESEARCH

Both aerobic glycolysis and mitochondrial respiration are required for osteoclast differentiation

(2020) Boer Li et al.   FASEB JOURNAL

Hypoxia inhibits ferritinophagy, increases mitochondrial ferritin, and protects from ferroptosis

(2020) Dominik C. Fuhrmann et al.   Redox Biology

Schisandrin A restrains osteoclastogenesis by inhibiting reactive oxygen species and activating Nrf2 signalling

(2020) Shuo Ni et al.   CELL PROLIFERATION

Distinct roles for the hypoxia-inducible transcription factors HIF-1α and HIF-2α in human osteoclast formation and function

(2020) Helen J. Knowles   Scientific Reports

Ferroptosis as a target for protection against cardiomyopathy

(2019) Xuexian Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Iron-dependent CDK1 activity promotes lung carcinogenesis via activation of the GP130/STAT3 signaling pathway

(2019) Yanbin Kuang et al.   Cell Death & Disease

Macrophage-specific HIF-1α contributes to impaired autophagic flux in non-alcoholic steatohepatitis

(2018) Xiaojing Wang et al.   HEPATOLOGY

BAP1 links metabolic regulation of ferroptosis to tumour suppression

(2018) Yilei Zhang et al.   NATURE CELL BIOLOGY

Characterization of ferroptosis in murine models of hemochromatosis

(2017) Hao Wang et al.   HEPATOLOGY

Tau-mediated iron export prevents ferroptotic damage after ischemic stroke

(2017) Q-z Tuo et al.   MOLECULAR PSYCHIATRY

NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis

(2017) Samantha W. Alvarez et al.   NATURE

Ferroptosis is an autophagic cell death process

(2016) Minghui Gao et al.   CELL RESEARCH

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

(2014) Joseph D. Mancias et al.   NATURE

Synchronized renal tubular cell death involves ferroptosis

(2014) Andreas Linkermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIF1  is required for osteoclast activation by estrogen deficiency in postmenopausal osteoporosis

(2013) Y. Miyauchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Hypoxia and hypoxia inducible factors: Diverse roles in liver diseases

(2011) Bharath Nath et al.   HEPATOLOGY

Autophagy regulates hypoxia-induced osteoclastogenesis through the HIF-1α/BNIP3 signaling pathway

(2011) Yi Zhao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol

(2010) D. R. Richardson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acute hypoxia and osteoclast activity: a balance between enhanced resorption and increased apoptosis

(2009) Helen J Knowles et al.   JOURNAL OF PATHOLOGY

Coordination of PGC-1β and iron uptake in mitochondrial biogenesis and osteoclast activation

(2009) Kiyo-aki Ishii et al.   NATURE MEDICINE

An Angiogenesis Inhibitor, 2-Methoxyestradiol, Involutes Rat Collagen-Induced Arthritis and Suppresses Gene Expression of Synovial Vascular Endothelial Growth Factor and Basic Fibroblast Growth Factor

(2008) Ernest Brahn et al.   JOURNAL OF RHEUMATOLOGY

Osteoclast size is controlled by Fra-2 through LIF/LIF-receptor signalling and hypoxia

(2008) Aline Bozec et al.   NATURE