Article
Chemistry, Physical
Constantinos Voniatis, Dora Barczikai, Gergo Gyulai, Angela Jedlovszky-Hajdu
Summary: This manuscript presents the first attempt to fabricate and characterise electrospun polycaprolactone/poly(succinimide) composite meshes, which show great potential for diverse applications. Three different meshes were produced using different electrospinning configurations, and physical-chemical and mechanical characterisation confirmed the advantages of the composite meshes in terms of mechanical strength and wettability.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Polymer Science
Fatemeh Dehghan, Adeleh Gholipour-Kanani, Mehdi Kamali Dolatabadi, Seyed Hajir Bahrami
Summary: In this study, nanofibrous webs loaded with different amounts of aloe vera extract were fabricated using electrospinning technique. The PCL-PEG-aloe vera nanofibers with a 1:1:1 mass ratio exhibited a bead-less bimodal morphology consisting of nano-scale and micro-scale fibers, and showed higher mechanical strength and cell compatibility compared to unloaded nanofibers. The nanofibrous scaffolds incorporated with aloe vera extract also exhibited excellent ability for bone repair, as confirmed by the higher amount of calcium deposition.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Materials Science, Multidisciplinary
Yuxin Li, Dianyu Wang, Eryun Yan, Jianwei Gao, Yan Wang, Shaobin Li, Yuwei Wang, Liquan Fan, Shengnan Chen, Deqing Zhang
Summary: Xylan/PCL core-shell nanofibers were successfully prepared using coaxial electrospinning, and they exhibited good degradation performance under acidic or neutral conditions. These nanofibers can act as drug carriers and showed excellent bactericidal activity.
Article
Polymer Science
Lucia F. A. Amorim, Raul Fangueiro, Isabel C. Gouveia
Summary: In this study, needleless electrospinning technology was used to fabricate flexirubin-loaded polyvinyl alcohol/kefiran/polycaprolactone nanofibers. The nanofibers exhibited beadless morphology with stable mechanical properties. The fabricated nanofibers showed high antioxidant activity and the ability to reduce enzymatic browning.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Polymer Science
Cristina Busuioc, Andrada-Elena Alecu, Claudiu-Constantin Costea, Mihaela Beregoi, Mihaela Bacalum, Mina Raileanu, Sorin-Ion Jinga, Iuliana-Mihaela Deleanu
Summary: This study reports the synthesis and characterization of polycaprolactone fibers loaded with particulate calcium magnesium silicates, which form composite materials with bioresorbable and bioactive properties. The fibrous composites were fabricated by electrospinning and showed a significant reduction in fiber diameter after the loading stage. The silicate phases exhibited high bioactivity and enriched the potential of the polymeric host, providing both biocompatibility and bioresorbability.
Article
Chemistry, Physical
Izabella Rajzer, Monika Rom, Elzbieta Menaszek, Janusz Fabia, Ryszard Kwiatkowski
Summary: The study aimed to investigate the effects of PCL/n-HAp scaffolds modified with a conductive polymer-polyaniline on bone cell growth and proliferation. The material was prepared using electrospinning and ink-jet printing methods, and analyzed using various techniques. The results showed that the material was able to promote the growth and proliferation of bone cells.
Article
Materials Science, Textiles
E. San Martin-Martinez, R. Casanas-Pimentel, A. Almaguer-Flores, G. Prado-Prone, A. Garcia-Garcia, C. Landa-Solis, A. Hernandez-Rangel
Summary: The addition of curcumin to PCL-COL composite membranes enhances their mechanical properties and antibacterial effects, making them promising candidates for wound management. The degradation rate and wettability of the membranes are also suitable for skin tissue regeneration.
FIBERS AND POLYMERS
(2022)
Article
Chemistry, Applied
Adrian Rojas, Eliezer Velasquez, Constanza Pina, Maria Jose Galotto, Carol Lopez de Dicastillo
Summary: The study investigated the influence of core/shell electrospun mats based on CA and PCL on the release of Quer and Cur, revealing that the CA/PCL coaxial structure could effectively slow down the diffusion rate of both active agents.
CARBOHYDRATE POLYMERS
(2021)
Article
Materials Science, Multidisciplinary
Sundarapandian Subramanian, Sathish Kumar Karuppannan, Raghavendra Ramalingam, Mohammed Junaid Hussain Dowlath, S. B. Mohamed Khalith, Shazia Anjum Musthafa, V. Chitra, Ganesh Munuswamy-Ramanujam, Kantha Deivi Arunachalam
Summary: In this study, Gymnema sylvestre leaf extract was incorporated into polycaprolactone (PCL) nanofiber, which resulted in the synthesis of beadless, hydrophilic, and continuous nanofibers with surface mediated antibacterial activity and enhanced proliferation of fibroblast cells, suitable for wound care applications.
Article
Materials Science, Multidisciplinary
Eryun Yan, Jinyu Jiang, Xihua Ren, Jianwei Gao, Xunhai Zhang, Shuhua Li, Shengnan Chen, Yuxin Li
Summary: Polymer nanofibers with pH-responsive properties were successfully prepared by coaxial electrospinning, which can be used as carriers for anticancer drug paclitaxel (PTX) and effectively degrade under acidic or neutral condition, showing good inhibitory effects on colon cancer cells.
Article
Engineering, Biomedical
Jiafeng Wang, Longhui Shao, Xiaoyu Wu, Chun Liu, Su Ni, Ting Dai, Hongwei Liu, Hongbin Zhao
Summary: Osteoblasts and osteoclasts play a crucial role in bone regeneration and remodeling. Incorporating naringenin and vitamin K2 stimulates osteogenesis-related genes and proteins while inhibiting the formation and growth of osteoclasts.
MATERIALS TODAY BIO
(2023)
Article
Polymer Science
Hannah A. Lacy, Vera Jencova, Sarka Hauzerova, Andrei Stanishevsky
Summary: Nanofibers made from blending natural and synthetic biopolymers have shown potential for better mechanical stability, ECM morphology mimicry, and cellular interaction. This study focuses on AC-electrospinning of poorly miscible blends of gelatin and polycaprolactone, and the results demonstrate the effect of the blend ratio on wettability, crystallinity, and structure. Preliminary in vitro tests confirm favorable cell attachment, proliferation, and spreading on the nanofibrous meshes.
JOURNAL OF APPLIED POLYMER SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Amirhossein Mohammadi, Morteza Koruji, Mahmoud Azami, Ronak Shabani, Sanam Mohandesnezhad, Zahra Bashiri, Hamidreza Asgari
Summary: This article discusses the development of biocompatible tubular scaffolds using electrospinning. These scaffolds, made from polycaprolactone, decellularized extracellular matrix from ram testicular tissue, and graphene oxide nanoparticles, aim to mimic the structural properties of seminiferous tubules for in vitro spermatogenesis support.
MACROMOLECULAR BIOSCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Hao-Hsi Kao, Chang-Yi Kuo, Darshan Tagadur Govindaraju, Kuo-Su Chen, Jyh-Ping Chen
Summary: This study aims to investigate the effect of chitosan (CS) on the cellular response of mesothelial cells cultured in a polycaprolactone (PCL) and PCL/CS blend nanofiber scaffold. The results show that the incorporation of CS improves scaffold hydrophilicity, enhances cell attachment, and better maintains the mesothelial phenotype. In vivo experiments demonstrate that the cell/scaffold construct containing allograft mesothelial cells can be used for mesothelium reconstruction.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Engineering, Environmental
Shaghayegh Sheikhzadeh, Mohammad Alizadeh Khaledabad, Hadi Almasi
Summary: This study aimed to fabricate and optimize polycaprolactone/xanthan electrospun nanofibers using design of experiment. A central composite design was constructed to investigate the effects of blend ratio, voltage, flow rate, and spinning distance on the fiber diameter, standard deviation, and contact angle. The results showed that the blend ratio was critical for obtaining desired nanofiber properties, while voltage, flow rate, and spinning distance also had significant effects. The model demonstrated the potential for producing fine, uniform nanofibers with moderate wettability, suitable for food and biological applications.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2023)
Article
Polymer Science
Dominik de Cassan, Alexander Becker, Birgit Glasmacher, Yvonne Roger, Andrea Hoffmann, Thomas R. Gengenbach, Christopher D. Easton, Robert Hansch, Henning Menzel
JOURNAL OF APPLIED POLYMER SCIENCE
(2020)
Article
Cell & Tissue Engineering
Elmar Willbold, Mathias Wellmann, Bastian Welke, Nina Angrisani, Sarah Gniesmer, Andreas Kampmann, Andrea Hoffmann, Dominik de Cassan, Henning Menzel, Anna Lena Hoheisel, Birgit Glasmacher, Janin Reifenrath
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE
(2020)
Article
Nanoscience & Nanotechnology
Catharina Husteden, Falko Doberenz, Nathalie Goergen, Shashank Reddy Pinnapireddy, Christopher Janich, Andreas Langner, Frank Syrowatka, Alexandros Repanas, Frank Erdmann, Jarmila Jedelska, Udo Bakowsky, Thomas Groth, Christian Woelk
ACS APPLIED MATERIALS & INTERFACES
(2020)
Article
Biology
Vitalii Mutsenko, Sven Knaack, Lothar Lauterboeck, Dmytro Tarusin, Bulat Sydykov, Ramon Cabiscol, Dmitrii Ivnev, Jan Belikan, Annemarie Beck, Daniele Dipresa, Anja Lode, Thaqif El Khassawna, Marian Kampschulte, Roland Scharf, Alexander Yu. Petrenko, Sotirios Korossis, Willem F. Wolkers, Michael Gelinsky, Birgit Glasmacher, Oleksandr Gryshkov
Article
Multidisciplinary Sciences
Sarah Gniesmer, Ralph Brehm, Andrea Hoffmann, Dominik de Cassan, Henning Menzel, Anna Lena Hoheisel, Birgit Glasmacher, Elmar Willbold, Janin Reifenrath, Nils Ludwig, Ruediger Zimmerer, Frank Tavassol, Nils-Claudius Gellrich, Andreas Kampmann
Article
Biochemistry & Molecular Biology
Olena Pogozhykh, Nicola Hofmann, Oleksandr Gryshkov, Constantin von Kaisenberg, Marc Mueller, Birgit Glasmacher, Denys Pogozhykh, Martin Boergel, Rainer Blasczyk, Constanca Figueiredo
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Polymer Science
Dierk Fricke, Alexander Becker, Annice Heratizadeh, Sara Knigge, Lennart Juette, Merve Wollweber, Thomas Werfel, Bernhard Wilhelm Roth, Birgit Glasmacher
Review
Polymer Science
Sinduja Suresh, Alexander Becker, Birgit Glasmacher
Review
Engineering, Biomedical
Leal-Marin Sara, Kern Thomas, Hofmann Nicola, Pogozhykh Olena, Framme Carsten, Borgel Martin, Figueiredo Constanca, Glasmacher Birgit, Gryshkov Oleksandr
Summary: Human amniotic membrane (hAM) is widely used in tissue engineering, particularly in skin dressing and corneal treatment, due to its extracellular matrix structure and excellent biological properties. Recent research focuses on enhancing hAM performance by creating scaffolds mimicking the native membrane structure. Preservation techniques for maintaining biological functions such as angiogenesis, anti-inflammation, antifibrotic, and antibacterial activity are also essential for native hAM and tissue-engineered products.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
(2021)
Article
Biotechnology & Applied Microbiology
Eva Vonbrunn, Marc Mueller, Melanie Pichlsberger, Monika Sundl, Alexander Helmer, Stefanie Angela Wallner, Beate Rinner, Alexandru-Cristian Tuca, Lars-Peter Kamolz, Dagmar Brislinger, Birgit Glasmacher, Ingrid Lang-Olip
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2020)
Article
Dentistry, Oral Surgery & Medicine
T. Hildebrand, L. Nogueira, P. T. Sunde, D. Orstavik, B. Glasmacher, H. J. Haugen
Summary: The methodology introduced in this study utilizes phosphotungstic acid (PTA) as a contrast-enhancement agent to visualize dental ultrastructures, including cellular and soft tissue components, by performing high-resolution nano-CT scans. The staining protocol allows for the concomitant visualization of hard tissues along with cellular layers and soft tissues in teeth.
INTERNATIONAL ENDODONTIC JOURNAL
(2021)
Article
Biochemistry & Molecular Biology
Oleksandr Gryshkov, Vitalii Mutsenko, Dmytro Tarusin, Diaa Khayyat, Ortwin Naujok, Ekaterina Riabchenko, Yuliia Nemirovska, Arseny Danilov, Alexander Y. Petrenko, Birgit Glasmacher
Summary: Alginate, a versatile natural biomaterial, is widely used in the biomedical field for its unique features such as biocompatibility and biodegradability. Core-shell capsules made from low viscosity high-G alginate show superior stability during in vitro culture and promote the formation of viable self-assembled cellular structures and maintenance of MSCs functionality compared to other materials. The proposed workflow of preparation, culture, and cryopreservation of core-shell capsules with self-assembled cellular structures appears to be a promising strategy for their off-the-shelf availability.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Materials Science, Multidisciplinary
Sara Knigge, Marc Mueller, Lara Fricke, Tobias Schilling, Birgit Glasmacher
Summary: Magnesium is a promising metal for resorbable cardiovascular implants due to its biocompatibility, corrosion tendency, and mechanical properties. A protective polymeric layer can slow down the corrosion rate, and coatings can improve tissue interaction. This study examines the corrosion mechanism of coated magnesium and finds that spin coatings provide efficient protection with a significantly lower corrosion rate. However, the degradation of the protective layer is accelerated by magnesium corrosion.
Review
Polymer Science
Christina Maria Winkler, Antonia Isabel Kuhn, Gesine Hentschel, Birgit Glasmacher
Summary: This study explores the advantages of using hydrogels as PIV channel materials and their properties in cardiovascular applications. Hydrogels have optical and mechanical properties that can match the refractive index of the fluid. By measuring the optical and mechanical properties, suitable hydrogel materials can be selected.
Article
Thermodynamics
Ali Chitsazan, Georg Klepp, Birgit Glasmacher
Summary: Jet impingements enhance heat and mass transfer rates in industrial drying machines. The study of heat transfer between multiple jets and a moving curved surface is difficult due to changing boundaries and surface curvature effects. The use of the SST k-omega turbulence model has shown reasonable accuracy in simulating real geometries for industrial drying applications.
INTERNATIONAL JOURNAL OF HEAT AND TECHNOLOGY
(2021)