Article
Chemistry, Multidisciplinary
Ibrahim Khan, Saud Bawazeer, Abdur Rauf, Muhammad Nasimullah Qureshi, Naveed Muhammad, Yahya S. Al-Awthan, Omar Bahattab, Aneela Maalik, Kannan R. R. Rengasamy
Summary: The study demonstrates the efficient synthesis of silver nanoparticles using alcoholic extracts of black cumin seeds, showing significant pharmacological activities and potential for various medical applications.
JOURNAL OF NANOSTRUCTURE IN CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Omar Bahattab, Ibrahim Khan, Sami Bawazeer, Abdur Rauf, Muhammad Nasimullah Qureshi, Yahya S. Al-Awthan, Naveed Muhammad, Ajmal Khan, Muhammad Akram, Mohammad Nazmul Islam, Talha Bin Emran
Summary: Gold nanoparticles (Au-NPs) capped and stabilized with black cumin seed alcohol extract were successfully synthesized, showing fast, simple, and environmentally friendly characteristics. The Au-NPs were characterized using various techniques, demonstrating good stability under different pH levels, salt concentrations, and temperatures. Additionally, the Au-NPs exhibited promising bio-activities, making them suitable for applications in the biomedical and pharmaceutical industries.
GREEN PROCESSING AND SYNTHESIS
(2021)
Article
Plant Sciences
Mudasir Hafiz Khan, Niyaz Ahmad Dar, Bashir Ahmad Alie, Ghulam Hassan Mir, Uzma Fayaz, Azra Khan, Basharat Bashir, Ajaz Ahmad, Sheikh Mansoor, Yong Suk Chung, Seong Heo
Summary: Bunium persicum, a valuable medicinal plant, faces challenges in widespread cultivation due to seed dormancy and a lengthy seed-to-seed cycle. This study evaluated the germination behavior and seed dormancy of six genotypes of Bunium persicum collected from different altitudes. The findings suggest that specific treatments and growth media can break seed dormancy, promote early tuber development, and improve germination percentage and growth.
Article
Food Science & Technology
Soumaya Bourgou, Iness Bettaieb Rebey, Sofiene Ben Kaab, Majdi Hammami, Sarra Dakhlaoui, Selmi Sawsen, Kamel Msaada, Hiroko Isoda, Riadh Ksouri, Marie-Laure Fauconnier
Summary: Comparative study on the extraction of bioactive lipids from black cumin and basil seeds using conventional petroleum-based solvent and green solvent MeTHF showed that MeTHF extraction resulted in higher oil yield and more abundant nutrients. The oils extracted with MeTHF had higher tocopherols and phenolic compounds content, stronger antioxidant activities, and similar anti-inflammatory capacity compared to hexane-extracted oils.
Article
Agricultural Engineering
Tianmiao Huang, Di Liu, Xiuwen Cui, Meiling Li, Ling Jin, Paul W. Pare, Mengfei Li, Jianhe Wei
Summary: This study successfully cultivated seedlings of the traditional Chinese medicine Angelica sinensis by inducing embryogenic callus, suspension cell culture, bioactive metabolite determination, and plantlet acclimatization. The highest growth rate and bioactive metabolite contents were observed under the optimal treatment conditions, leading to the successful establishment of robust plants.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Review
Materials Science, Multidisciplinary
Biruk Fentahun Adamu, Jing Gao, Abdul Khalique Jhatial, Degu Melaku Kumelachew
Summary: Modern wound dressings are now incorporating functional materials like electrospun nanofibers to assist in wound healing and tissue regeneration. These dressings also provide breathability for cellular growth and have potential applications in drug delivery systems.
MATERIALS & DESIGN
(2021)
Article
Agricultural Engineering
Seyyed Ali Sadegh Sadat Darakeh, Weria Weisany, Nawroz Abdul-Razzak Tahir, Peer M. Schenk
Summary: The aim of this study was to find a natural method to enhance the growth of black cumin and reduce dependence on mineral fertilizers. The results showed that vermicompost and arbuscular mycorrhizal fungi treatments significantly increased the fresh and dry weights of black cumin plants. These treatments also had positive effects on chlorophyll content, relative water content, and micronutrient uptake.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Review
Nutrition & Dietetics
Ahmed A. Zaky, Jae-Han Shim, A. M. Abd El-Aty
Summary: Black cumin cake, a natural waste material generated after pressing the oil, is rich in nutritional value and has been extensively developed by scientists and food manufacturers due to its antioxidants properties. Despite the vast amounts of cake by-products not effectively utilized, the bioactive peptides contained within could be valuable additives in various industries.
FRONTIERS IN NUTRITION
(2021)
Article
Medicine, Legal
George A. Burdock
Summary: The food ingredient Nigella sativa L., also known as black cumin or black caraway, has a long history of use in Middle- and Far-Eastern cultures. The seed and its extracts have been reported as a successful therapeutic agent, with the presence of thymoquinone being attributed to its effectiveness. However, the quantitative analysis of the seed yields variable results, which can be due to various factors. Despite this variability, many studies have shown positive outcomes in toxicity testing and clinical trials. Some allergic reactions have been reported when N. sativa extracts are applied to the skin. Nevertheless, when consumed at historical levels and as traditionally practiced, N. sativa seeds are considered safe.
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2022)
Article
Plant Sciences
Abdalrhaman M. Salih, Fahad Al-Qurainy, Salim Khan, Mohammad Nadeem, Mohamed Tarroum, Hassan O. Shaikhaldein
Summary: This study synthesized silver nanoparticles and investigated their effects on phytochemical production in Juniperus procera callus. The results showed that silver nanoparticles significantly affected biomass accumulation, non-enzymatic antioxidants, and the production of bioactive compounds.
FRONTIERS IN PLANT SCIENCE
(2022)
Review
Chemistry, Medicinal
Nguyen Thi Thuy Linh, Nguyen Thi Thu Ha, Nguyen Thanh Tra, Le Thi Tu Anh, Nguyen Van Tuyen, Ninh The Son
Summary: Centipeda minima, a medicinal plant used for treating whooping cough, nasal allergy, malaria, and asthma, has more than a hundred isolated compounds with various biological activities such as anti-cancer, anti-bacterial, anti-allergy, anti-viral, anti-inflammatory, and hepatoprotective properties. The use of C. minima plant extracts and isolated compounds for drug development appears to be a promising strategy due to its bioactive results, especially in anti-cancer and anti-inflammatory effects.
MINI-REVIEWS IN MEDICINAL CHEMISTRY
(2021)
Article
Agronomy
Nima Abbasi, Yousef Sohrabi, Hawre Kiani
Summary: Improving water productivity is an effective strategy for managing irrigation under water deficit conditions. A factorial experiment was conducted to investigate the effect of irrigation regimes and tragacanth gum concentrations on black cumin plants. The results showed that reduced irrigation led to negative effects on various plant traits, while the application of tragacanth gum at proper concentrations improved these traits and increased grain weight, especially under drought stress conditions.
AGRICULTURAL WATER MANAGEMENT
(2023)
Article
Agriculture, Dairy & Animal Science
Ahmed A. A. Abdel-Wareth, Saskia Kehraus, Karl -Heinz Suedekum
Summary: The study showed that oregano leaves and their PBLC can significantly improve the growth performance, nutrient digestibility, and organ functions of rabbits, while reducing fecal ammonia concentration and serum cholesterol levels.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Md Abdul Hannan, Md Sarwar Zahan, Partha Protim Sarker, Akhi Moni, Hunjoo Ha, Md Jamal Uddin
Summary: Black cumin and its vital compound, thymoquinone, have shown protective effects against kidney injury caused by various xenobiotics through antioxidation, anti-inflammation, anti-apoptosis, and antifibrosis mechanisms. Clinical trials have demonstrated improvements in blood and urine parameters in advanced CKD patients. However, further research is needed to explore targeted delivery mechanisms and to gather more clinical evidence for recommending black cumin to CKD patients.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Claudia Novais, Carla Pereira, Adriana K. Molina, Angela Liberal, Maria Ines Dias, Mikel Anibarro-Ortega, Maria Jose Alves, Ricardo C. Calhelha, Isabel C. F. R. Ferreira, Lillian Barros
Summary: The research evaluated the nutritional and chemical profiles of four condiment mixtures, highlighting their bioactive properties such as antioxidant, antimicrobial, anti-inflammatory, and antitumor effects. The study found that these mixtures are rich sources of bioactive compounds with health benefits, supporting their importance in human diet as a good dietary practice.
Article
Agronomy
Era Vaidya Malhotra, Rishu Jain, Saurabh Tyagi, K. Venkat Raman, Sangita Bansal, Debasis Pattanayak
Summary: This study compares the miRNA profiles of Helicoverpa armigera-infested and undamaged adjacent leaves of Cajanus scarabaeoides, revealing the important regulatory role of miRNAs in the plant-insect interactions and systemic defence responses. The miRNA response in the unfed leaves indicates their involvement in inducing defence pathway genes.
PEST MANAGEMENT SCIENCE
(2022)
Article
Genetics & Heredity
Shasthree Taduri, Raju Bheemanahalli, Chathurika Wijewardana, Ajaz A. A. Lone, Stephen L. L. Meyers, Mark Shankle, Wei Gao, K. Raja Reddy
Summary: Plants, especially sweetpotato, are significantly affected by climate change-induced stresses, such as elevated carbon dioxide, high temperature, and drought stress. This study found that these stresses, alone or in combination, have a significant negative impact on sweetpotato growth and yield. However, elevated carbon dioxide can alleviate some of the damaging effects of high temperature and drought stress, leading to increased storage root weights. Cultivar selection plays a crucial role in stress tolerance, with Hatteras being the most tolerant and LA 1188 being sensitive to these stresses.
FRONTIERS IN GENETICS
(2023)
Article
Biochemistry & Molecular Biology
Rakesh Singh, Akshay Singh, Ajay Kumar Mahato, Ritu Paliwal, Gunjan Tiwari, Ashok Kumar
Summary: This study generated a whole transcriptome profile of A. paniculata and identified a total of 22,402 high-quality transcripts. The functional annotation revealed their involvement in molecular function, biological processes, and cellular component. Transcription factor analysis validated the presence of 15 TF genes belonging to NAC, MYB, and bHLH categories. In addition, the study predicted 102 transcripts encoding enzymes involved in the biosynthesis of terpenoids and identified 4254 EST-SSRs for assessing genetic diversity among A. paniculata accessions.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Mudasir Hafiz Khan, Niyaz Ahmad Dar, Bashir Ahmad Alie, Sher Ahmad Dar, Ajaz Ahmad Lone, Ghulam Hassan Mir, Uzma Fayaz, Sajad Ali, Anshika Tyagi, Mohamed A. El-Sheikh, Saleh Alansi
Summary: The present study evaluated the variability of essential oil composition in Kala zeera seed extract obtained from different geographical zones using GC-MS. Significant differences in essential oil content and chemical constituents were observed. PCA grouped four significant compounds into the same cluster, mainly distributed in two zones. The results suggest the existence of variability among bioactive compounds of B. persicum, which could be incorporated into potential drugs and genetic sources for breeding programs.
Article
Multidisciplinary Sciences
Pradeep Ruperao, Prasad Bajaj, Rajkumar Subramani, Rashmi Yadav, Vijaya Bhaskar Reddy B. Lachagari, Sivarama Prasad Lekkala, Abhishek Rathore, Sunil Archak, Ulavappa Angadi, Rakesh Singh, Kuldeep Singh, Sean Mayes, Parimalan Rangan
Summary: To reduce genome sequence representation, RAD-seq protocols using single-digest or double-digest methods are widely used. This study compared the single and double-digest RAD-seq methods by genotyping a pilot-scale sesame population. Analysis of the resulting data showed significant differences in k-mer count, gene presence absence variation (PAV), and variant calling between the two methods. Combining variants from both datasets helped identify the most diverse samples and sub-groups in the sesame population.
Article
Agronomy
Shruti, Alka Shukla, Saman Saim Rahman, Poonam Suneja, Rashmi Yadav, Zakir Hussain, Rakesh Singh, Shiv Kumar Yadav, Jai Chand Rana, Sangita Yadav, Rakesh Bhardwaj
Summary: Amaranth and buckwheat, two pseudo-cereals, are highly nutritious, gluten-free, and have religious significance as fasting food. Evaluation of germplasm resources is essential for utilizing their potential in crop improvement programs. In this study, NIRS-based machine learning models were developed to predict nutritional traits in amaranth and buckwheat, with good prediction capabilities and applicability confirmed through screening of germplasm. This enables the identification of trait-specific germplasm as gene sources and aids in crop improvement programs.
Article
Agronomy
Gautam Vats, Dimpi Das, Rajat Gupta, Akshay Singh, Avantika Maurya, S. Rajkumar, Amit Kumar Singh, Rakesh Bharadwaj, Sandeep Kumar, Surinder Kumar Kaushik, Veena Gupta, Kuldeep Singh, Rakesh Singh
Summary: This study aimed to assess the genetic diversity among 94 Amaranthus hypochondriacus accessions using genome-wide SSR markers. The results showed that population structure analysis resulted in two major genetic clusters, suggesting the presence of shared genomic regions among the accessions regardless of their geographical origin. The high allelic frequency and heterozygosity levels indicate significant genetic variability in the germplasm, which can be further used in future breeding programs.
Article
Agronomy
Debjani Roy Choudhury, Ramesh Kumar, Avantika Maurya, Dinesh P. Semwal, Ranbir S. Rathi, Raj K. Gautam, Ajaya K. Trivedi, Santosh K. Bishnoi, Sudhir P. Ahlawat, Kuldeep Singh, Nagendra K. Singh, Rakesh Singh
Summary: This study investigated the genetic diversity and geographical isolation of 298 rice landraces from six different regions of India using SSR and SNP marker systems. The results showed that rice landraces from Uttar Pradesh were the most diverse, and complete geographical isolation was observed with SSR markers. Population structure analysis revealed different clustering patterns among regions with SSR and SNP markers. The study concluded that unlinked SSR markers showed better geographical isolation than a large set of SNP markers.
Article
Plant Sciences
Tilak Chandra, Sarika Jaiswal, Mir Asif Iquebal, Rakesh Singh, R. K. Gautam, Anil Rai, Dinesh Kumar
Summary: miRNAs play a crucial role in improving rice through various means, such as large-scale genotyping, phenotyping, genome editing, marker-assisted selection, and genomic selection. Understanding the function of miRNAs helps to avoid ambiguity and redundancy in data generation. miRNAs primarily function in growth and development, as well as biotic and abiotic stresses in rice. Two extensively studied miRNA families (family 156 and family 396) orchestrate advantageous agronomical traits.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Article
Multidisciplinary Sciences
Racheal John, Haritha Bollinedi, Christine Jeyaseelan, Siddhant Ranjan Padhi, Neha Sajwan, Dhrubjyoti Nath, Rakesh Singh, Sudhir Pal Ahlawat, Rakesh Bhardwaj, Jai Chand Rana
Summary: The study conducted nutritional profiling of 395 Assam rice landraces for various traits. The results revealed high diversity and nutritional potential in these landraces, including low glycemic index varieties. Correlations between different traits were found, and multivariate analyses identified clusters of accessions with distinct nutritional attributes. These findings have implications for cultivar development and breeding programs.
Article
Food Science & Technology
D. D. Deepika, Siddhant Ranjan Padhi, Padmavati G. Gore, Kuldeep Tripathi, Ashvinkumar Katral, Rahul Chandora, G. J. Abhishek, Vishal Kondal, Rakesh Singh, Rakesh Bharadwaj, Kailash C. Bhatt, Jai Chand Rana, Amritbir Riar
Summary: The adzuki bean, known for its rich nutritional composition, has the potential to address food and nutritional security for low socioeconomic classes and vegetarian populations worldwide. This study analyzed 100 diverse adzuki bean accessions and identified significant genotype variations for various nutritional traits. Promising accessions with high protein content and antioxidant activity were identified, and correlation analyses and principal component analysis provided insights into intertrait relationships. Nutri-dense accessions with high ash and protein content and low phytic acid were also identified, providing practical support for the development of high-value food and feed varieties.
Article
Plant Sciences
Manju Kumari, Siddhant Ranjan Padhi, Sushil Kumar Chourey, Vishal Kondal, Swapnil S. Thakare, Ankita Negi, Veena Gupta, Mamta Arya, Jeshima Khan Yasin, Rakesh Singh, Chellapilla Bharadwaj, Atul Kumar, Kailash Chandra Bhatt, Rakesh Bhardwaj, Jai Chand Rana, Tanay Joshi, Amritbir Riar
Summary: Horsegram is an underutilized pulse crop with significant nutritional variability. This study assessed the nutritional profile of 139 horsegram germplasm lines from various Indian states and identified promising accessions with desirable traits. The findings highlight the potential of horsegram for future food and nutritional security.
