Polycystin‐1 regulates cardiomyocyte mitophagy

Mitophagy and mitochondrial integrity in cardiac ischemia-reperfusion injury

(2019) Mingjie Yang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Polycystin-1 Assembles with Kv Channels to Govern Cardiomyocyte Repolarization and Contractility

(2019) Francisco Altamirano et al.   CIRCULATION

The pathobiology of polycystic kidney disease from a metabolic viewpoint

(2019) Luis Fernando Menezes et al.   Nature Reviews Nephrology

Emerging role of mitophagy in cardiovascular physiology and pathology

(2019) Pablo E. Morales et al.   MOLECULAR ASPECTS OF MEDICINE

Mul1 restrains Parkin-mediated mitophagy in mature neurons by maintaining ER-mitochondrial contacts

(2019) Rajat Puri et al.   Nature Communications

FOXO1 inhibition prevents renal ischemia–reperfusion injury via cAMP‐response element binding protein/PPAR‐γ coactivator‐1α‐mediated mitochondrial biogenesis

(2019) Di Wang et al.   BRITISH JOURNAL OF PHARMACOLOGY

FOXO1 inhibition potentiates endothelial angiogenic functions in diabetes via suppression of ROCK1/Drp1-mediated mitochondrial fission

(2018) Yundi Shi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mechanical stretch increases L-type calcium channel stability in cardiomyocytes through a polycystin-1/AKT-dependent mechanism

(2018) A. Córdova-Casanova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Down Syndrome Critical Region 1 Gene,Rcan1, Helps Maintain a More Fused Mitochondrial NetworkNovelty and Significance

(2018) Valentina Parra et al.   CIRCULATION RESEARCH

A cleavage product of Polycystin-1 is a mitochondrial matrix protein that affects mitochondria morphology and function when heterologously expressed

(2018) Cheng-Chao Lin et al.   Scientific Reports

Inhibition of ERK-Drp1 signaling and mitochondria fragmentation alleviates IGF-IIR-induced mitochondria dysfunction during heart failure

(2018) Chih-Yang Huang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

FoxO1 Promotes Mitophagy in the Podocytes of Diabetic Male Mice via the PINK1/Parkin Pathway

(2017) Wen Li et al.   ENDOCRINOLOGY

Mitochondria as a target of cardioprotection in models of preconditioning

(2017) Magdaléna Jašová et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Mitochondrial Abnormality Facilitates Cyst Formation in Autosomal Dominant Polycystic Kidney Disease

(2017) Yu Ishimoto et al.   MOLECULAR AND CELLULAR BIOLOGY

The polycystins are modulated by cellular oxygen-sensing pathways and regulate mitochondrial function

(2017) Valeria Padovano et al.   MOLECULAR BIOLOGY OF THE CELL

Mito-Morphosis: Mitochondrial Fusion, Fission, and Cristae Remodeling as Key Mediators of Cellular Function

(2016) Lena Pernas et al.   Annual Review of Physiology

Mitochondrial dynamics and cell death in heart failure

(2016) José Marín-García et al.   HEART FAILURE REVIEWS

PINK1 disables the anti-fission machinery to segregate damaged mitochondria for mitophagy

(2016) Kenneth R. Pryde et al.   JOURNAL OF CELL BIOLOGY

Deciphering the Molecular Signals of PINK1/Parkin Mitophagy

(2016) Thanh N. Nguyen et al.   TRENDS IN CELL BIOLOGY

Fatty Acid Oxidation is Impaired in An Orthologous Mouse Model of Autosomal Dominant Polycystic Kidney Disease

(2016) Luis F. Menezes et al.   EBioMedicine

Polycystin-1 Is a Cardiomyocyte Mechanosensor That Governs L-Type Ca2+ Channel Protein Stability

(2015) Z. Pedrozo et al.   CIRCULATION

FOXO1 silence aggravates oxidative stress-promoted apoptosis in cardiomyocytes by reducing autophagy

(2015) Yuzhen Ning et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

PINK1 Is Dispensable for Mitochondrial Recruitment of Parkin and Activation of Mitophagy in Cardiac Myocytes

(2015) Dieter A. Kubli et al.   PLoS One

Mitochondrial fission is required for cardiomyocyte hypertrophy mediated by a Ca2+-calcineurin signaling pathway

(2014) C. Pennanen et al.   JOURNAL OF CELL SCIENCE

Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia

(2014) TingTing Hong et al.   NATURE MEDICINE

FoxO transcription factors: their roles in the maintenance of skeletal muscle homeostasis

(2013) Anthony M. J. Sanchez et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Insulin Stimulates Mitochondrial Fusion and Function in Cardiomyocytes via the Akt-mTOR-NF B-Opa-1 Signaling Pathway

(2013) V. Parra et al.   DIABETES

Mitochondrial dynamics: regulatory mechanisms and emerging role in renal pathophysiology

(2013) Ming Zhan et al.   KIDNEY INTERNATIONAL

Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy

(2013) Isaline Rowe et al.   NATURE MEDICINE

Parallel activation of Ca2+-induced survival and death pathways in cardiomyocytes by sorbitol-induced hyperosmotic stress

(2010) M. Chiong et al.   APOPTOSIS

Cyclic AMP-mediated cyst expansion

(2010) Darren P. Wallace   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Inflammation, Oxidative Stress, and Insulin Resistance in Polycystic Kidney Disease

(2010) V. Menon et al.   Clinical Journal of the American Society of Nephrology

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

PI-3-K and AKT: Onto the mitochondria☆

(2009) Bangyan L. Stiles   ADVANCED DRUG DELIVERY REVIEWS

Iron induces protection and necrosis in cultured cardiomyocytes: Role of reactive oxygen species and nitric oxide

(2009) Juan Pablo Munoz et al.   FREE RADICAL BIOLOGY AND MEDICINE

FoxO Transcription Factors Promote Autophagy in Cardiomyocytes

(2009) Arunima Sengupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY