4.5 Article

Dihalogenation of Alkenes Using Combinations of N-Halosuccinimides and Alkali Metal Halides

Journal

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2021, Issue 33, Pages 4762-4766

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.202100811

Keywords

Alkenes; Electrophilic additions; Halides; Halogenation; Synthetic methods

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This method for vicinal dihalogenation of alkenes is simple, efficient, and eco-friendly, utilizing environmentally benign solvents and avoiding purification steps. Pure products are typically obtained through a simple aqueous workup.
A simple, efficient and eco-friendly method for the vicinal dihalogenation of alkenes is described. The reaction is performed with a combination of a N-halosuccinimide and an alkali metal halide using environmentally benign solvents such as acetic acid and ethyl acetate. Purification steps are avoided, and pure products are usually obtained after a simple aqueous workup.

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