Review
Biochemistry & Molecular Biology
Maria Lantzanaki, Theofanis Vavilis, Vikentia C. Harizopoulou, Helen Bili, Dimitrios G. Goulis, Dimitrios Vavilis
Summary: This review presents the role of ceramides during pregnancy and obstetrical adverse outcomes, as well as their potential as biomarkers in such conditions.
Article
Medicine, General & Internal
Alice Ronco, Sofia Roero, Silvana Arduino, Arianna Arese, Isabella Ferrando, Gabriella Scaltrito, Viola Casula, Teresa Fea, Mattia Mazza, Carlotta Bossotti, Roberto Zizzo, Alberto Revelli
Summary: This study analyzed the specific effects of gestational diabetes mellitus (GDM) on twin pregnancy outcomes. The results showed that compared to GDM singleton pregnancies, GDM twins had higher rates of preeclampsia, cesarean section, and neonatal hypoglycemia. Compared to twin pregnancies without GDM, women with GDM twins were older, had higher BMI, had a higher incidence of large-for-gestational-age (LGA) newborns, and a lower incidence of low APGAR scores. Overall, GDM does not worsen outcomes of twin pregnancy.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Hui Liang, Ning-Ping Pan, Yin-Feng Wang, Chao-Shuang Ye, Zhu-Qing Yan, Rui-Jin Wu
Summary: This study evaluated the obstetrical and oncological progression of twin pregnancies with hydatidiform mole coexisting fetus (HMCF). The results showed that complete hydatidiform mole coexisting fetus (CHMCF) had a higher incidence rate than partial hydatidiform mole coexisting fetus (PHMCF), and continuing pregnancy did not increase the risk of gestational trophoblastic neoplasia (GTN).
TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY
(2022)
Article
Obstetrics & Gynecology
Iben Katinka Greiber, Jakob Hansen Viuff, Lene Mellemkjaer, Cristel Sorensen Hjortshoj, Ojvind Lidegaard, Lone Storgaard, Mona Aarenstrup Karlsen
Summary: Cancer during pregnancy increases the risk of induced abortion and planned premature birth. Neonates born to mothers with cancer in pregnancy have a higher risk of neonatal morbidity and mortality.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2022)
Review
Oncology
Carlo Ronsini, Lavinia Mosca, Irene Iavarone, Roberta Nicoletti, Davide Vinci, Raffaela Maria Carotenuto, Francesca Pasanisi, Maria Cristina Solazzo, Pasquale De Franciscis, Marco Torella, Marco La Verde, Nicola Colacurci, Luigi Cobellis, Giuseppe Vizzielli, Stefano Restaino
Summary: Conservative management can be considered as an option for young women with grade 2, stage IA endometrial cancer who wish to preserve their fertility. The combination of levonorgestrel-releasing intra-uterine device and systemic therapy can result in a high rate of complete response. However, fertility-sparing treatment is not the current standard of care for young women with endometrial cancer.
FRONTIERS IN ONCOLOGY
(2022)
Review
Obstetrics & Gynecology
Lone Storgaard, Iben Katinka Greiber, Berit Woetmann Pedersen, Birgitte Bruun Nielsen, Mona Aarenstrup Karlsen
Summary: Cancer in pregnancy presents clinical and ethical challenges, but treatment regimens have become more similar to those of non-pregnant patients. Chemotherapy treatment in pregnancy has been proven to be safe after the first trimester. Multidisciplinary teams should manage cancer in pregnancy, considering staging, treatment, social and mental care, delivery timing, and infant follow-up. Centralization and advisory boards are recommended due to the rarity and lack of expertise.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2023)
Article
Oncology
Julie Labrosse, Anne Lecourt, Alice Hours, Clara Sebbag, Aullene Toussaint, Enora Laas, Florence Coussy, Beatriz Grandal, Elise Dumas, Eric Daoud, Charlotte Morel, Jean-Guillaume Feron, Matthieu Faron, Jean-Yves Pierga, Fabien Reyal, Anne-Sophie Hamy
Summary: This study investigated the time to pregnancy and outcomes after breast cancer treatment in survivors aged 18-43 years old. It found that menstrual cycles before pregnancy were significantly associated with time to pregnancy, and that neonatal outcomes were similar to the general population. Breast cancer treatments did not affect newborn parameters.
Article
Obstetrics & Gynecology
Stephanie A. Leonard, Iman Berrahou, Adary Zhang, Brent Monseur, Elliott K. Main, Juno Obedin-Maliver
Summary: This study aims to evaluate the disparities in obstetrical and birth outcomes between sexual and/or gender minority individuals and non-sexual and/or gender minority individuals. The results show that birthing patients in mother-mother partnerships have higher rates of multifetal gestation, labor induction, postpartum hemorrhage, severe morbidity, and nontransfusion severe morbidity compared to birthing patients in mother-father partnerships. However, no significant differences were found between father birthing patients in any partnership and birthing patients in mother-father partnerships in terms of adverse obstetrical and birth outcomes.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Article
Oncology
Gabriel J. Rendon, Aldo Lopez Blanco, Alejandro Aragona, Jose Martin Saadi, Julian Di Guilmi, Clemente Arab Eblen, Fernando Heredia Munoz, Rene Pareja
Summary: This study reviewed 25 cases of patients with cervical tumors >= 2 cm and indicated that neo-adjuvant chemotherapy followed by fertility-sparing surgery is feasible in well-selected patients, with a majority successfully preserving fertility. Future studies should focus on the timing of lymphadenectomy and type of cervical surgery.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2021)
Article
Gastroenterology & Hepatology
Yassine Kilani, Iqra Arshad, Mohammad Aldiabat, Rinku Rani Bhatija, Saqr Alsakarneh, Aljabiri Yazan, Ebehiwele Ebhohon, Fnu Vikash, Vikash Kumar, Syeda Ashna Fatima Kamal, Priscila Castro Puello, Laith Numan, Maria Kassab
Summary: This study examined the association between autoimmune hepatitis (AIH) and adverse obstetrical outcomes, such as preterm delivery, using a nationwide database. The results showed that pregnant females with AIH had a significantly higher risk of preterm delivery compared to those without chronic liver diseases.
DIGESTIVE DISEASES AND SCIENCES
(2023)
Article
Obstetrics & Gynecology
S. Shinkai, S. Ishioka, T. Mariya, Y. Fujibe, M. Kim, M. Someya, T. Saito
Summary: Vaginal radical trachelectomy during pregnancy does not affect the obstetrical prognosis of patients with early invasive uterine cervical cancer and may be an acceptable treatment modality for them. However, it should be performed carefully from an oncological perspective due to the risk of recurrence.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2022)
Article
Surgery
Stefi Nordkamp, Eva L. K. Voogt, Desley M. G. van Zoggel, Anna Martling, Torbjorn Holm, Gabriella Jansson Palmer, Chikako Suzuki, Joost Nederend, Miranda Kusters, Jacobus W. A. Burger, Harm J. T. Rutten, Henrik Iversen
Summary: No standard of care has been defined in the treatment of locally recurrent rectal cancer due to its heterogeneous nature, low incidence, and varied treatment options. This study compared data from two tertiary hospitals and found that aiming for wide resection margins increased the R0 resection rate and local re-recurrence-free survival. Neoadjuvant full-course chemoradiotherapy improved survival, while reirradiation showed no benefit.
BRITISH JOURNAL OF SURGERY
(2022)
Article
Psychiatry
Ester Di Giacomo, Rodolfo Pessina, Valeria Placenti, Francesca Pescatore, Fabrizia Colmegna, Massimo Clerici
Summary: Therapeutic termination of pregnancy may lead to depressive symptoms but can improve with time and professional support. Twelve percent of women developed post-traumatic stress disorder, emphasizing the importance of mental health implications and the need for appropriate treatment.
PSYCHIATRY RESEARCH
(2022)
Review
Acoustics
S. Sorrenti, D. Di Mascio, A. Khalil, N. Persico, F. D'antonio, F. Zullo, V. D'ambrosio, G. Greenberg, J. Hasson, F. Vena, L. Muzii, R. Brunelli, A. Giancotti
Summary: This study evaluated outcomes of dichorionic twin pregnancies undergoing early vs late selective termination of pregnancy. The results showed that the risk of pregnancy loss prior to 24 weeks was lower in the early-ST group, and the risks of preterm birth and low birth weight were also lower. Therefore, the importance of early diagnosis of fetal anomalies in twin pregnancies was highlighted.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2023)
Article
Obstetrics & Gynecology
Neta Doctory, Asaf Romano, Inbal Navon, Shiri Barbash-Hazan, Ron Bardin, Eran Hadar
Summary: This study found that lateral placentation may be associated with increased risk of preterm birth and cesarean delivery compared to central placentation.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Obstetrics & Gynecology
Tal Margaliot Kalifa, Hen Y. Sela, Jordanna Joseph, Sorina Grisaru-Granovsky, Fayez Khatib, Misgav Rottenstreich
Summary: Pregnancies following a second trimester uterine evacuation do not have an increased risk of preterm delivery or other adverse perinatal outcomes compared to pregnancies following a first trimester uterine evacuation.
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
(2024)
Article
Obstetrics & Gynecology
Dominique A. Badr, Mieke M. Cannie, Caroline Kadji, Xin Kang, Andrew Carlin, Jacques C. Jani
Summary: The objective of this study was to assess the influence of the test-to-delivery interval on the performance of ultrasound and MRI in predicting birthweight. The results showed that MRI performed best in predicting birthweight greater than gestational age if delivery occurred within two weeks of the examination, with a slight decrease thereafter, while ultrasound performance decreased drastically over time.
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
(2024)
Article
Obstetrics & Gynecology
Corina N. Schoen, Sami Backley, Lauren Orr, Amrita Roy, Tiffany Corlin, Alexander B. Knee
Summary: This retrospective cohort study aimed to evaluate whether induction of labor is associated with a lower risk of cesarean section in patients with isolated polyhydramnios. The study found that planned induction was associated with a lower rate of cesarean delivery compared to expectant management, but the difference was not statistically significant. Additionally, no differences were observed in maternal or fetal secondary outcomes.
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
(2024)
Article
Obstetrics & Gynecology
Ohad Houri, Asaf Romano, Yossi Geron, Gil Zeevi, Eran Hadar, Shiri Barbash-Hazan, Shir Danieli-Gruber
Summary: Women with prior uterine rupture have good maternal and neonatal outcomes in subsequent pregnancies when managed at a tertiary medical center, with planned elective term cesarean delivery, or even earlier, at the onset of spontaneous preterm labor.
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
(2024)
Correction
Obstetrics & Gynecology
Laura E. Janssen, Marjon A. de Boer, Eline C. E. von Konigslow, Elisa Dal, Martijn A. Oudijk, Danielle Robbers-Visser, Christianne J. M. de Groot
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
(2024)
Review
Obstetrics & Gynecology
Natalia Rzewuska, Jacek Kunicki, Katarzyna Pieniak, Paulina Laskus, Bernadeta Zabielska, Roman Smolarczyk, Michal Kunicki
Summary: This systematic review examined the comorbidity of idiopathic intracranial hypertension (IIH) and polycystic ovarian syndrome (PCOS) and their impact on metabolism, hormone levels, and reproduction. The findings showed a high prevalence of comorbidity between the two conditions, which may have significant clinical implications for patient management.
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
(2024)