New bioactive 5-arylcarboximidamidopyrazolo[3,4-c]pyridines: Synthesis, cytotoxic activity, mechanistic investigation and structure-activity relationships

Title
New bioactive 5-arylcarboximidamidopyrazolo[3,4-c]pyridines: Synthesis, cytotoxic activity, mechanistic investigation and structure-activity relationships
Authors
Keywords
Purine analogues, Pyrazolopyridine, Cytotoxicity, Apoptosis, Cell cycle analysis, Akt, ERK, p38 MAPK
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 218, Issue -, Pages 113387
Publisher
Elsevier BV
Online
2021-03-20
DOI
10.1016/j.ejmech.2021.113387

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