Review
Cardiac & Cardiovascular Systems
Suzanne Oskouie, Faith Michael, Sera Whitelaw, Biykem Bozkurt, Gregg C. Fonarow, Harriette G. C. Van Spall
Summary: This study aimed to develop quality indicators for transitional care after hospitalization for heart failure. Through a systematic review of clinical trials, the researchers generated a list of process indicators, structure indicators, patient-reported indicators, and clinical indicators that can be used to guide clinical practice and research.
EUROPEAN JOURNAL OF HEART FAILURE
(2023)
Article
Public, Environmental & Occupational Health
Alicja Wisnicka, Katarzyna Lomper, Izabella Uchmanowicz
Summary: The self-care outcomes and quality of life scores of men with chronic heart failure are unsatisfactory.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Surgery
Nicholas A. Schreiter, Alexander Fisher, James R. Barrett, Alexandra Acher, Laura Sell, Dani Edwards, Glen Leverson, Alyssa Joachim, Sharon M. Weber, Daniel E. Abbott
Summary: This study found that a surgical transitional care program improved patient understanding of post-discharge care responsibilities, provided better educational materials, and increased overall hospital experience ratings. Although the transitional care program incurred higher costs, it did not adversely affect hospital margins.
Article
Multidisciplinary Sciences
James McMahon, Christine Brown Wilson, Loreena Hill, Paul Tierney, David R. Thompson, Jan Cameron, Doris Yu, Debra K. Moser, Karen Spilsbury, Nittaya Srisuk, Jos M. G. A. Schols, Marielle Van der Velden, Gary Mitchell
Summary: This study aims to design a digital intervention to improve care home staff knowledge of heart failure (HF) and optimize quality of life for those living with the condition in long-term residential care. The study will involve three workstreams: understanding the current knowledge and practices of care home staff regarding HF, co-designing the digital intervention with HF patients, professionals, and care home staff, and testing the feasibility of the intervention. With limited research in this area, the resulting digital intervention is expected to have relevance for HF care globally. Rating: 8/10.
Review
Nursing
Yuan Li, Mei R. Fu, Jinbo Fang, Hong Zheng, Biru Luo
Summary: Transitional care interventions have been proven effective in reducing mortality and improving quality of life for individuals with heart failure, with greater efficacy seen in trials delivered by multidisciplinary teams. However, the effects on emotional distress are inconclusive, highlighting the need for further research.
INTERNATIONAL JOURNAL OF NURSING STUDIES
(2021)
Article
Cardiac & Cardiovascular Systems
Ersilia M. DeFilippis, John Henderson, Kelly M. Axsom, Maria Rosa Costanzo, Philip B. Adamson, Alan B. Miller, Marie-Elena Brett, Michael M. Givertz
Summary: The study found that after one year, heart failure patients could reduce pulmonary artery pressure and hospitalization frequency through cardiovascular monitoring, and gender did not affect the treatment effect. This study shows that ambulatory hemodynamic monitoring provides similar benefits for male and female heart failure patients.
CIRCULATION-HEART FAILURE
(2021)
Article
Nursing
Hilal Kucukkaya, Ilknur Munevver Gonenc
Summary: This study aimed to determine the prevalence and predictive factors of sexual dysfunction and quality of sexual life in women with heart failure. The majority of participants had sexual dysfunction, mainly a reduction in sexual desire. Menopausal women are seven times more likely to develop sexual dysfunction than non-menopausal women.
JOURNAL OF CLINICAL NURSING
(2023)
Article
Cardiac & Cardiovascular Systems
Elliane Irani, Harleah G. Buck, Karen S. Lyons, Seunghee Margevicius, Ercole Vellone, Andrew Bugajski, Maddalena De Maria
Summary: This study aimed to investigate how congruence in and satisfaction with the appraisal of dyadic HF care type contribute to the quality of life for both patients and caregivers. The results showed that congruent appraisal was positively associated with caregivers' mental quality of life, while satisfaction with care type was positively associated with physical and mental quality of life for both patients with HF and caregivers.
EUROPEAN JOURNAL OF CARDIOVASCULAR NURSING
(2023)
Article
Multidisciplinary Sciences
Maria F. Paton, John Gierula, Judith E. Lowry, David A. Cairns, Kieran Bose Rosling, Charlotte A. Cole, Melanie McGinlay, Sam Straw, Rowena Byrom, Richard M. Cubbon, Mark T. Kearney, Klaus K. Witte
Summary: The study aimed to compare personalized pacemaker reprogramming with usual care on echocardiographic and patient-oriented outcomes. Results showed that personalized programming reduced RV pacing, improved LV function and size, and extended battery longevity, with no impact on quality of life.
Article
Cardiac & Cardiovascular Systems
Alice Ravera, Bernadet T. Santema, Iziah E. Sama, Sven Meyer, Carlo M. Lombardi, Valentina Carubelli, Joao Pedro Ferreira, Chim C. Lang, Kenneth Dickstein, Stefan D. Anker, Nilesh J. Samani, Faiez Zannad, Dirk J. van Veldhuisen, John R. Teerlink, Marco Metra, Adriaan A. Voors
Summary: In patients with HFrEF, women reported significantly worse QoL than men at baseline, but both genders showed improvement in QoL at follow-up. The KCCQ-OS demonstrated the strongest independent association with outcome compared to the EQ-5D scores.
EUROPEAN JOURNAL OF HEART FAILURE
(2021)
Article
Cardiac & Cardiovascular Systems
Alice Ravera, Bernadet T. Santema, Iziah E. Sama, Sven Meyer, Carlo M. Lombardi, Valentina Carubelli, Joao Pedro Ferreira, Chim C. Lang, Kenneth Dickstein, Stefan D. Anker, Nilesh J. Samani, Faiez Zannad, Dirk J. van Veldhuisen, John R. Teerlink, Marco Metra, Adriaan A. Voors
Summary: This study compared quality of life measures derived from two widely used questionnaires in clinical trials, the KCCQ and EQ-5D, in men and women with heart failure. Women had significantly worse baseline QoL compared to men, but both genders showed improvement at follow-up. The KCCQ overall score (KCCQ-OS) showed the strongest association with mortality compared to EQ-5D scores.
EUROPEAN JOURNAL OF HEART FAILURE
(2021)
Article
Multidisciplinary Sciences
Lotte Verweij, Adrianne C. M. Petri, Janet L. MacNeil-Vroomen, Patricia Jepma, Corine H. M. Latour, Ron J. G. Peters, Wilma J. M. Scholte Op Reimer, Bianca M. Buurman, Judith E. Bosmans
Summary: The study found that the CCB program did not significantly reduce the risk of readmission or mortality in older cardiac patients, and there was no significant difference in societal costs. However, the QALYs were significantly lower in the intervention group compared to the usual care group.
Review
Cardiac & Cardiovascular Systems
Rod S. Taylor, Hasnain M. Dalal, Ann-Dorthe Zwisler
Summary: Cardiac rehabilitation is often overlooked in the treatment of heart failure. This review provides an update on the evidence, guidelines, and status of cardiac rehabilitation for heart failure patients. It argues that exercise-based rehabilitation is a crucial aspect of heart failure management, alongside medication and medical devices, as it improves patient outcomes, including their quality of life. To improve access and participation, healthcare services should offer heart failure patients a range of evidence-based rehabilitation options, including home-based programs with digital technology and traditional center-based programs, based on disease stage and patient preference.
EUROPEAN HEART JOURNAL
(2023)
Article
Geriatrics & Gerontology
Marlene Patrick, Brenda Miller, Beverly Will, James F. Bena, Shannon L. Morrison, Lee Anne Siegmund
Summary: The purpose of this study was to investigate perceptions of heart failure quality of life and its relationship to self-care moderated by anxiety and depression. The results showed that as the quality of life and anxiety or depression scores increased, self-care management scores decreased. However, higher heart failure quality of life and lower anxiety and depression scores were associated with increased self-care management. The findings emphasize the importance of nursing interventions and research focusing on symptom recognition among older adults with heart failure.
Article
Cardiac & Cardiovascular Systems
Mikhail N. Kosiborod, Christiane E. Angermann, Sean P. Collins, John R. Teerlink, Piotr Ponikowski, Jan Biegus, Josep Comin-Colet, Joao Pedro Ferreira, Robert J. Mentz, Michael E. Nassif, Mitchell A. Psotka, Jasper Tromp, Martina Brueckmann, Jonathan P. Blatchford, Afshin Salsali, Adriaan A. Voors
Summary: In patients hospitalized for acute heart failure, empagliflozin improved symptoms, physical limitations, and quality of life, with benefits seen as early as 15 days and maintained through 90 days. The study demonstrated clinical benefit of empagliflozin regardless of baseline symptomatic impairment.
Review
Cardiac & Cardiovascular Systems
Eloisa Colin-Ramirez, Nariman Sepehrvand, Sarah Rathwell, Heather Ross, Jorge Escobedo, Peter Macdonald, Richard Troughton, Clara Saldarriaga, Fernando Lanas, Robert Doughty, Finlay A. McAlister, Justin A. Ezekowitz
Summary: This study analyzed data from randomized controlled trials to evaluate the effects of sodium restriction on clinical outcomes in heart failure patients. The results showed that sodium restriction did not reduce the risk of death or hospitalization, but it may improve symptoms and quality of life.
CIRCULATION-HEART FAILURE
(2023)
Review
Cardiac & Cardiovascular Systems
Stephen J. Greene, Johann Bauersachs, Jasper J. Brugts, Justin A. Ezekowitz, Carolyn S. P. Lam, Lars H. Lund, Piotr Ponikowski, Adriaan A. Voors, Faiez Zannad, Shelley Zieroth, Javed Butler
Summary: Heart failure (HF) is a progressive disease with periods of stability interrupted by worsening HF (WHF) episodes. The definition of WHF has evolved to include events outside of hospitalization. While most HF clinical trials focus on hospitalization and death, recent studies are investigating WHF regardless of care location. This article reviews the evolving definition of WHF, emphasizes its importance as a new phase in HF, summarizes recent clinical trials on novel therapies, and outlines unmet needs in WHF identification and treatment.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Muhammad Shahzeb Khan, Harriette G. C. Van Spall
JACC-HEART FAILURE
(2023)
Article
Health Care Sciences & Services
Weijie Sun, Sunil Vasu Kalmady, Nariman Sepehrvand, Amir Salimi, Yousef Nademi, Kevin Bainey, Justin A. Ezekowitz, Russell Greiner, Abram Hindle, Finlay A. McAlister, Roopinder K. Sandhu, Padma Kaul
Summary: This study explored the feasibility and value of using electrocardiogram (ECG) data to predict mortality risk among emergency and hospitalized patients. By developing and validating machine learning models based on ECG traces, the study showed that deep learning models outperformed models based on ECG measurements in predicting short-term and long-term mortality. The findings highlight the potential of ECG-based models for prognostication at point of care.
NPJ DIGITAL MEDICINE
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Mohamed B. Jalloh, Christopher B. Granger, Gregg C. Fonarow, Harriette G. C. Van Spall
EUROPEAN HEART JOURNAL
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Gregg C. Fonarow, Harriette G. C. Van Spall, James L. Januzzi
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Muhammad Shahzeb Khan, Sumitabh Singh, Matthew W. Segar, Muhammad Shariq Usman, Neil Keshvani, Andrew P. Ambrosy, Mona Fiuzat, Harriette G. C. Van Spall, Gregg C. Fonarow, Faiez Zannad, G. Michael Felker, James L. Januzzi, Christopher O'Connor, Javed Butler, Ambarish Pandey
Summary: This study aimed to evaluate the impact of polypharmacy on the receipt of optimal guideline-directed medical therapy (GDMT) among patients with heart failure with reduced ejection fraction (HFrEF) over time.
JACC-HEART FAILURE
(2023)
Article
Cardiac & Cardiovascular Systems
Muhammad Shahzeb Khan, Matthew W. Segar, Muhammad Shariq Usman, Kershaw V. Patel, Harriette G. C. Van Spall, Adam D. Devore, Muthiah Vaduganathan, Carolyn S. P. Lam, Faiez Zannad, Subodh Verma, Javed Butler, W. H. Wilson Tang, Ambarish Pandey
Summary: In the CANVAS program, canagliflozin was found to reduce the risk of heart failure hospitalization among individuals with type 2 diabetes mellitus. Two diabetes-specific risk scores, WATCH-DM and TRS-HFDM, can reliably identify those at high risk and most likely to benefit from canagliflozin treatment.
JACC-HEART FAILURE
(2023)
Article
Cardiac & Cardiovascular Systems
Ruoting Wang, Hertzel C. Gerstein, Harriette G. C. Van Spall, Gregory Y. H. Lip, Ivan Olier, Sandra Ortega-Martorell, Lehana Thabane, Zebing Ye, Guowei Li
Summary: This study found a significant association between calculated remnant cholesterol (RC) and risk of heart failure (HF) in patients with diabetes mellitus (DM). Elevated RC levels were associated with an increased risk of HF, highlighting the importance of RC management in patients with DM for HF risk management.
EUROPEAN HEART JOURNAL-QUALITY OF CARE AND CLINICAL OUTCOMES
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Justin A. Ezekowitz
CANADIAN JOURNAL OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Zahra Raisi-Estabragh, Ofer Kobo, Jennifer H. Mieres, Renee P. Bullock-Palmer, Harriette G. C. Van Spall, Khadijah Breathett, Mamas A. Mamas
Summary: This descriptive epidemiologic study outlines trends and disparities in obesity-related cardiovascular mortality in the US population between 1999 and 2020. The study suggests that obesity-related cardiovascular mortality is increasing with differential trends by race, sex, and place of residence.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Tauben Averbuch, Stephen J. Greene, Harriette G. C. Van Spall
JACC-HEART FAILURE
(2023)
Article
Cardiac & Cardiovascular Systems
Debra D. Dixon, Shannon M. Knapp, Onyedika Ilonze, Sabra C. Lewsey, Sula Mazimba, Selma Mohammed, Harriette G. C. Van Spall, Khadijah Breathett
Summary: This study examines racial and ethnic differences in ventricular assist device (VAD) implantation rates and post-implantation survival among patients with ambulatory heart failure. The study finds that black patients have higher VAD implantation rates and better post-VAD survival compared to white and Hispanic patients.
JACC-HEART FAILURE
(2023)
Letter
Cardiac & Cardiovascular Systems
Ruoting Wang, Hertzel C. Gerstein, Harriette G. C. Van Spall, Gregory Y. H. Lip, Ivan Olier, Sandra Ortega-Martorell, Lehana Thabane, Zebing Ye, Guowei Li
EUROPEAN HEART JOURNAL-QUALITY OF CARE AND CLINICAL OUTCOMES
(2023)
Article
Medicine, General & Internal
Akshay Valsaraj, Sunil Vasu Kalmady, Vaibhav Sharma, Matthew Frost, Weijie Sun, Nariman Sepehrvand, Marcus Ong, Cyril Equilbec, Jason R. B. Dyck, Todd Anderson, Harald Becher, Sarah Weeks, Jasper Tromp, Chung-Lieh Hung, Justin A. Ezekowitz, Padma Kaul
Summary: In this study, machine learning models based on echocardiography were developed to predict all-cause mortality. The models showed high accuracy and correlated with patients' quality of life. These models can be used for automated risk stratification in clinical settings.