Harmful algal blooms and shellfish in the marine environment: an overview of the main molluscan responses, toxin dynamics, and risks for human health

Marine invertebrate interactions with Harmful Algal Blooms - implications for One Health

(2021) Andrew D. Turner et al.   JOURNAL OF INVERTEBRATE PATHOLOGY

Cinnamaldehyde Could Reduce the Accumulation of Diarrhetic Shellfish Toxins in the Digestive Gland of the Mussel Perna viridis under Laboratory Conditions

(2021) Guo-Fang Duan et al.   Marine Drugs

The Importance of Marine Bivalves in Invasive Host–Parasite Introductions

(2021) Katie E. Costello et al.   Frontiers in Marine Science

Effects of marine harmful algal blooms on bivalve cellular immunity and infectious diseases: A review

(2020) Malwenn Lassudrie et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Detoxification of paralytic shellfish poisoning toxins in naturally contaminated mussels, clams and scallops by an industrial procedure

(2020) Ana G. Cabado et al.   FOOD AND CHEMICAL TOXICOLOGY

Are invasive species always negative to aquatic ecosystem services? The role of dark false mussel for water quality improvement in a multi-impacted urban coastal lagoon

(2020) Raquel A.F. Neves et al.   WATER RESEARCH

Harmful algal blooms (red tide): a review of causes, impacts and approaches to monitoring and prediction

(2019) E. Zohdi et al.   International Journal of Environmental Science and Technology

Impacts of the toxic benthic dinoflagellate Prorocentrum lima on the brown mussel Perna perna: Shell-valve closure response, immunology, and histopathology

(2019) Raquel A.F. Neves et al.   MARINE ENVIRONMENTAL RESEARCH

Harmful algal blooms: A climate change co-stressor in marine and freshwater ecosystems

(2019) Andrew W. Griffith et al.   HARMFUL ALGAE

Warming Amplifies the Frequency of Harmful Algal Blooms with Eutrophication in Chinese Coastal Waters

(2019) Xi Xiao et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Multi-species okadaic acid contamination and human poisoning during a massive bloom of Dinophysis acuminata complex in southern Brazil

(2019) L.L. Mafra et al.   HARMFUL ALGAE

Climate Change and Harmful Algal Blooms: Insights and perspective

(2019) Christopher J. Gobler   HARMFUL ALGAE

Bioactive extracellular compounds produced by the dinoflagellate Alexandrium minutum are highly detrimental for oysters

(2018) J. Castrec et al.   AQUATIC TOXICOLOGY

Histopathological Alterations in the Gonad of Megapitaria squalida (Mollusca: Bivalvia) Inhabiting a Heavy Metals Polluted Environment

(2018) Josué Alonso Yee-Duarte et al.   JOURNAL OF AQUATIC ANIMAL HEALTH

EU Regulatory Risk Management of Marine Biotoxins in the Marine Bivalve Mollusc Food-Chain

(2018) Micheál O’Mahony   Toxins

Tissue Distribution and Elimination of Ciguatoxins in Tridacna maxima (Tridacnidae, Bivalvia) Fed Gambierdiscus polynesiensis

(2018) Mélanie Roué et al.   Toxins

Recent Trends in Marine Phycotoxins from Australian Coastal Waters

(2017) Penelope Ajani et al.   Marine Drugs

Marine biotoxins and associated outbreaks following seafood consumption: Prevention and surveillance in the 21st century

(2017) Jonathan Nicolas et al.   Global Food Security-Agriculture Policy Economics and Environment

Neuroenzymatic activity and physiological energetics in Manila clam, Ruditapes philippinarum, during short-term sublethal exposure to harmful alga, Heterocapsa circularisquama

(2016) Leila Basti et al.   AQUATIC TOXICOLOGY

Evidence of the bioaccumulation of ciguatoxins in giant clams ( Tridacna maxima ) exposed to Gambierdiscus spp. cells

(2016) Mélanie Roué et al.   HARMFUL ALGAE

Immunological and physiological responses of the periwinkle Littorina littorea during and after exposure to the toxic dinoflagellate Alexandrium minutum

(2015) Raquel A.F. Neves et al.   AQUATIC TOXICOLOGY

The toxic dinoflagellate Alexandrium minutum disrupts daily rhythmic activities at gene transcription, physiological and behavioral levels in the oyster Crassostrea gigas

(2015) Damien Tran et al.   AQUATIC TOXICOLOGY

Prevalence and intensity of pathologies induced by the toxic dinoflagellate, Heterocapsa circularisquama, in the Mediterranean mussel, Mytilus galloprovincialis

(2015) Leila Basti et al.   AQUATIC TOXICOLOGY

Development of histopathological indices in the digestive gland and gonad of mussels: Integration with contamination levels and effects of confounding factors

(2015) Nagore Cuevas et al.   AQUATIC TOXICOLOGY

Differential okadaic acid accumulation and detoxification by oysters and mussels during natural and simulated Dinophysis blooms

(2015) Luiz Laureno Mafra et al.   FISHERIES SCIENCE

Exposure to toxic Alexandrium minutum activates the detoxifying and antioxidant systems in gills of the oyster Crassostrea gigas

(2015) Caroline Fabioux et al.   HARMFUL ALGAE

Differential inimical effects of Alexandrium spp. and Karenia spp. on cleavage, hatching, and two larval stages of Japanese pearl oyster Pinctada fucata martensii

(2015) Leila Basti et al.   HARMFUL ALGAE

Interaction between toxic dinoflagellate Alexandrium catenella exposure and disease associated with herpesvirus OsHV-1 μVar in Pacific oyster spat Crassostrea gigas

(2015) Malwenn Lassudrie et al.   HARMFUL ALGAE

Harmful algal blooms and climate change: Learning from the past and present to forecast the future

(2015) Mark L. Wells et al.   HARMFUL ALGAE

Saxitoxin Modulates Immunological Parameters and Gene Transcription in Mytilus chilensis Hemocytes

(2015) Allisson Astuya et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Quantitative histopathology of the Mediterranean mussel (Mytilus galloprovincialis L.) exposed to the harmful dinoflagellate Ostreopsis cf. ovata

(2015) F. Carella et al.   JOURNAL OF INVERTEBRATE PATHOLOGY

Physiological and pathological changes in the eastern oyster Crassostrea virginica infested with the trematode Bucephalus sp. and exposed to the toxic dinoflagellate Alexandrium fundyense

(2015) Malwenn Lassudrie et al.   JOURNAL OF INVERTEBRATE PATHOLOGY

Responses of the common periwinkle Littorina littorea to exposure to the toxic dinoflagellate Alexandrium minutum

(2015) Raquel A. F. Neves et al.   JOURNAL OF MOLLUSCAN STUDIES

Susceptibility of gametes and embryos of the eastern oyster, Crassostrea virginica, to Karenia brevis and its toxins

(2015) Anne Rolton et al.   TOXICON

Physiological responses of Manila clams Venerupis (=Ruditapes) philippinarum with varying parasite Perkinsus olseni burden to toxic algal Alexandrium ostenfeldii exposure

(2014) Malwenn Lassudrie et al.   AQUATIC TOXICOLOGY

Effects of the red tide dinoflagellate, Karenia brevis, on early development of the eastern oyster Crassostrea virginica and northern quahog Mercenaria mercenaria

(2014) Anne Rolton et al.   AQUATIC TOXICOLOGY

Flow cytometric assessment of morphology, viability, and production of reactive oxygen species ofCrassostrea gigasoocytes. Application to Toxic dinoflagellate (Alexandrium minutum) exposure

(2014) Nelly Le Goïc et al.   CYTOMETRY PART A

Impact and effects of paralytic shellfish poisoning toxins derived from harmful algal blooms to marine fish

(2014) Pedro Reis Costa   FISH AND FISHERIES

Apoptosis of hemocytes from lions-paw scallop Nodipecten subnodosus induced with paralyzing shellfish poison from Gymnodinium catenatum

(2014) Norma Estrada et al.   IMMUNOBIOLOGY

Responses of the ribbed mussel, Geukensia demissa, to the harmful algae Aureococcus anophagefferens and Heterosigma akashiwo

(2014) E. Galimany et al.   JOURNAL OF MOLLUSCAN STUDIES

Effects of the DinoflagellateAlexandrium catenellaon the Early Development of the Pacific OysterCrassostrea gigas

(2014) Cuimin Mu et al.   JOURNAL OF SHELLFISH RESEARCH

A Feedback Mechanism to Control Apoptosis Occurs in the Digestive Gland of the Oyster Crassostrea gigas Exposed to the Paralytic Shellfish Toxins Producer Alexandrium catenella

(2014) Jean-Luc Rolland et al.   Marine Drugs

Effects of In Vitro Exposure to Diarrheic Toxin Producer Prorocentrum lima on Gene Expressions Related to Cell Cycle Regulation and Immune Response in Crassostrea gigas

(2014) Reyna de Jesús Romero-Geraldo et al.   PLoS One

Genetic and genotoxic impacts in the oyster Crassostrea gigas exposed to the harmful alga Alexandrium minutum

(2013) Audrey M. Mat et al.   AQUATIC TOXICOLOGY

Uptake, transfer and elimination kinetics of paralytic shellfish toxins in common octopus (Octopus vulgaris)

(2013) Vanessa M. Lopes et al.   AQUATIC TOXICOLOGY

Impacts of a ‘black tide’ harmful algal bloom on rocky-shore intertidal communities on the West Coast of South Africa

(2013) G.M. Branch et al.   HARMFUL ALGAE

Host–parasite interactions: Marine bivalve molluscs and protozoan parasites, Perkinsus species

(2013) Philippe Soudant et al.   JOURNAL OF INVERTEBRATE PATHOLOGY

Transcriptional responses of Mytilus chilensis exposed in vivo to saxitoxin (STX)

(2013) Gustavo Núñez-Acuña et al.   JOURNAL OF MOLLUSCAN STUDIES

First Report of Contamination of the AbaloneHaliotis discus hannaiby Okadaic Acid and Yessotoxin

(2013) Ji Hoe Kim et al.   JOURNAL OF SHELLFISH RESEARCH

Physiological Effects and Biotransformation of PSP Toxins in the New Zealand Scallop,Pecten novaezelandiae

(2013) Andrea M. Contreras et al.   JOURNAL OF SHELLFISH RESEARCH

Exposure to the Neurotoxic Dinoflagellate, Alexandrium catenella, Induces Apoptosis of the Hemocytes of the Oyster, Crassostrea gigas

(2013) Walid Medhioub et al.   Marine Drugs

Genomics Study of the Exposure Effect of Gymnodinium catenatum, a Paralyzing Toxin Producer, on Crassostrea gigas' Defense System and Detoxification Genes

(2013) Norma García-Lagunas et al.   PLoS One

Trophic transfer of microcystins through the lake pelagic food web: Evidence for the role of zooplankton as a vector in fish contamination

(2013) Benoît Sotton et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Bioaccumulation and depuration of brevetoxins in the eastern oyster (Crassostrea virginica) and the northern quahog (= hard clam, Mercenaria mercenaria)

(2013) Andrew W. Griffith et al.   TOXICON

Effect of Azadinium spinosum on the feeding behaviour and azaspiracid accumulation of Mytilus edulis

(2012) Thierry Jauffrais et al.   AQUATIC TOXICOLOGY

Biomagnification or biodilution of microcystins in aquatic foodwebs? Meta-analyses of laboratory and field studies

(2012) Betina Kozlowsky-Suzuki et al.   HARMFUL ALGAE

Trophic transfer of brevetoxins to the benthic macrofaunal community during a bloom of the harmful dinoflagellate Karenia brevis in Sarasota Bay, Florida

(2012) V.M. Bricelj et al.   HARMFUL ALGAE

Effects of the toxic dinoflagellate Alexandrium catenella on histopathogical and escape responses of the Northern scallop Argopecten purpuratus

(2012) Hélène Hégaret et al.   HARMFUL ALGAE

Physiological, Pathological, and Defense Alterations in Manila Clams (Short-Neck Clams),Ruditapes philippinarum, Induced byHeterocapsa circularisquama

(2012) Leila Basti et al.   JOURNAL OF SHELLFISH RESEARCH

Sensitivity of gametes, fertilization, and embryo development of the Japanese pearl oyster, Pinctada fucata martensii, to the harmful dinoflagellate, Heterocapsa circularisquama

(2012) Leila Basti et al.   MARINE BIOLOGY

Paralytic Toxins Accumulation and Tissue Expression of α-Amylase and Lipase Genes in the Pacific Oyster Crassostrea gigas Fed with the Neurotoxic Dinoflagellate Alexandrium catenella

(2012) Jean-Luc Rolland et al.   Marine Drugs

Accumulation, Biotransformation, Histopathology and Paralysis in the Pacific Calico Scallop Argopecten ventricosus by the Paralyzing Toxins of the Dinoflagellate Gymnodinium catenatum

(2012) Amada Y. Escobedo-Lozano et al.   Marine Drugs

Effects of CO2 and the harmful alga Aureococcus anophagefferens on growth and survival of oyster and scallop larvae

(2012) SC Talmage et al.   MARINE ECOLOGY PROGRESS SERIES

Azaspiracid accumulation, detoxification and biotransformation in blue mussels (Mytilus edulis) experimentally fed Azadinium spinosum

(2012) Thierry Jauffrais et al.   TOXICON

Effects of Karenia brevis on clearance rates and bioaccumulation of brevetoxins in benthic suspension feeding invertebrates

(2011) Michael Echevarria et al.   AQUATIC TOXICOLOGY

In vitro interactions between several species of harmful algae and haemocytes of bivalve molluscs

(2011) Hélène Hégaret et al.   CELL BIOLOGY AND TOXICOLOGY

Distribution and selective elimination of paralytic shellfish toxins in different tissues of Octopus vulgaris

(2011) Ana Monteiro et al.   HARMFUL ALGAE

The globally distributed genus Alexandrium: Multifaceted roles in marine ecosystems and impacts on human health

(2011) Donald M. Anderson et al.   HARMFUL ALGAE

Effects of the Toxic DinoflagellateHeterocapsa circularisquamaon Larvae of the Pearl OysterPinctada Fucata Martensii(Dunker, 1873)

(2011) Leila Basti et al.   JOURNAL OF SHELLFISH RESEARCH

Evaluation of Genotoxicity in Gills and Hemolymph of ClamRuditapes decussatusFed with the Toxic DinoflagellateProrocentrum lima

(2011) Fernanda Flórez-Barrós et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

The Relevance of Marine Chemical Ecology to Plankton and Ecosystem Function: An Emerging Field

(2011) Adrianna Ianora et al.   Marine Drugs

Toxic effects of harmful benthic dinoflagellate Ostreopsis ovata on invertebrate and vertebrate marine organisms

(2011) Marco Faimali et al.   MARINE ENVIRONMENTAL RESEARCH

Relationship between valve activity, microalgae concentration in the water and toxin accumulation in the digestive gland of the Pacific oyster Crassostrea gigas exposed to Alexandrium minutum

(2011) Hansy Haberkorn et al.   MARINE POLLUTION BULLETIN

Uptake, distribution and depuration of paralytic shellfish toxins from Alexandrium minutum in Australian greenlip abalone, Haliotis laevigata

(2011) Natalie Dowsett et al.   TOXICON

Feeding mechanics as the basis for differential uptake of the neurotoxin domoic acid by oysters, Crassostrea virginica, and mussels, Mytilus edulis

(2010) Luiz L. Mafra et al.   AQUATIC TOXICOLOGY

Shellfish toxicity: human health implications of marine algal toxins

(2010) K. J. JAMES et al.   EPIDEMIOLOGY AND INFECTION

Mortality of the short-neck clam Ruditapes philippinarum induced by the toxic dinoflagellate Heterocapsa circularisquama

(2010) Leila Basti et al.   FISHERIES SCIENCE

Can increases in temperature stimulate blooms of the toxic benthic dinoflagellate Ostreopsis ovata?

(2010) Edna Granéli et al.   HARMFUL ALGAE

OCEAN CLIMATE CHANGE, PHYTOPLANKTON COMMUNITY RESPONSES, AND HARMFUL ALGAL BLOOMS: A FORMIDABLE PREDICTIVE CHALLENGE

(2010) Gustaaf M. Hallegraeff   JOURNAL OF PHYCOLOGY

Evidence of selection for resistance to paralytic shellfish toxins during the early life history of soft-shell clam,Mya arenaria, populations

(2010) V. M. Bricelj et al.   LIMNOLOGY AND OCEANOGRAPHY

Evidence for a Novel Marine Harmful Algal Bloom: Cyanotoxin (Microcystin) Transfer from Land to Sea Otters

(2010) Melissa A. Miller et al.   PLoS One

Comparative Study of Various Immune Parameters in Three Bivalve Species during a Natural Bloom of Dinophysis acuminata in Santa Catarina Island, Brazil

(2010) Danielle Ferraz Mello et al.   Toxins

Effects of the toxic dinoflagellate Heterocapsa circularisquama on the valve movement behaviour of the Manila clam Ruditapes philippinarum

(2009) Leila Basti et al.   AQUACULTURE

Behavioral responses of Crassostrea gigas exposed to the harmful algae Alexandrium minutum

(2009) Damien Tran et al.   AQUACULTURE

Effects of Alexandrium minutum exposure upon physiological and hematological variables of diploid and triploid oysters, Crassostrea gigas

(2009) Hansy Haberkorn et al.   AQUATIC TOXICOLOGY

Effects of the toxic dinoflagellate Alexandrium monilatum on survival, grazing and behavioral response of three ecologically important bivalve molluscs

(2009) Susan P. May et al.   HARMFUL ALGAE

Perkinsosis in the Manila clam Ruditapes philippinarum affects responses to the harmful-alga, Prorocentrum minimum

(2009) Hélène Hégaret et al.   JOURNAL OF EXPERIMENTAL MARINE BIOLOGY AND ECOLOGY

Consumption ofScrippsiella lachrymosaResting Cysts by the Eastern Oyster (Crassostrea virginica)

(2009) Agneta Persson et al.   JOURNAL OF SHELLFISH RESEARCH

The Eastern Mudsnail, Ilyanassa obsoleta, Actively Forages For, Consumes, And Digests Cysts Of The Dinoflagellate, Scrippsiella lachrymosa

(2009) Agneta Persson et al.   MALACOLOGIA

Combined effects of a parasite, QPX, and the harmful-alga, Prorocentrum minimum on northern quahogs, Mercenaria mercenaria

(2009) Hélène Hégaret et al.   MARINE ENVIRONMENTAL RESEARCH

Accumulation of paralytic shellfish toxins in digestive gland of Octopus vulgaris during bloom events including the dinoflagellate Gymnodinium catenatum

(2009) Pedro Reis Costa et al.   MARINE POLLUTION BULLETIN

Differential accumulation of paralytic shellfish toxins from Alexandrium minutum in the pearl oyster, Pinctada imbricata

(2009) Shauna A. Murray et al.   TOXICON

First evidence of azaspiracids (AZAs): A family of lipophilic polyether marine toxins in scallops (Argopecten purpuratus) and mussels (Mytilus chilensis) collected in two regions of Chile

(2009) A. López-Rivera et al.   TOXICON

Mechanisms contributing to low domoic acid uptake by oysters feeding on Pseudo-nitzschia cells. I. Filtration and pseudofeces production

(2008) LL Mafra et al.   Aquatic Biology

Detoxification of Pacific oysterCrassostrea gigasfed on diets ofSkeletonema costatumwith and without silt, following PSP contamination byAlexandrium minutum

(2008) Marielle Guéguen et al.   AQUATIC LIVING RESOURCES

Pathology and immune response of the blue mussel (Mytilus edulis L.) after an exposure to the harmful dinoflagellate Prorocentrum minimum

(2008) Eve Galimany et al.   HARMFUL ALGAE

Experimental exposure of the blue mussel (Mytilus edulis, L.) to the toxic dinoflagellate Alexandrium fundyense: Histopathology, immune responses, and recovery

(2008) Eve Galimany et al.   HARMFUL ALGAE

Deleterious effects of a nonPST bioactive compound(s) from Alexandrium tamarense on bivalve hemocytes

(2008) Susan E. Ford et al.   MARINE BIOLOGY

Non-Traditional Vectors for Paralytic Shellfish Poisoning

(2008) Jonathan Deeds et al.   Marine Drugs

Behavioral and physiological responses to PSP toxins in Mya arenaria populations in relation to previous exposure to red tides

(2008) SP MacQuarrie et al.   MARINE ECOLOGY PROGRESS SERIES

Paralytic shellfish poisoning toxin profile of mussels Perna perna from southern Atlantic coasts of Morocco

(2008) Rachid Abouabdellah et al.   TOXICON

Note on the occurrence of Pseudo-nitzschia australis and domoic acid in squid from Monterey Bay, CA (USA)

(2007) Sibel Bargu et al.   HARMFUL ALGAE

The effects of feeding Karlodinium veneficum (PLY # 103; Gymnodinium veneficum Ballantine) to the blue mussel Mytilus edulis

(2007) Eva Galimany et al.   HARMFUL ALGAE

Immunological responses of the Manila clam (Ruditapes philippinarum) with varying parasite (Perkinsus olseni) burden, during a long-term exposure to the harmful alga, Karenia selliformis, and possible interactions

(2007) Patricia Mirella da Silva et al.   TOXICON

Surveillance of algal toxins in shellfish from Scottish waters

(2007) L.A. Stobo et al.   TOXICON