Mycofactocin biosynthesis: modification of the peptide MftA by the radical S-adenosylmethionine protein MftC

The Radical S-Adenosyl-l-methionine Enzyme MftC Catalyzes an Oxidative Decarboxylation of the C-Terminus of the MftA Peptide

(2016) Nathan A. Bruender et al.   BIOCHEMISTRY

Demonstration That the RadicalS-Adenosylmethionine (SAM) Enzyme PqqE Catalyzesde NovoCarbon-Carbon Cross-linking within a Peptide Substrate PqqA in the Presence of the Peptide Chaperone PqqD

(2016) Ian Barr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The PqqD homologous domain of the radical SAM enzyme ThnB is required for thioether bond formation during thurincin H maturation

(2015) Beata M. Wieckowski et al.   FEBS LETTERS

The RadicalS-Adenosyl-l-methionine Enzyme QhpD Catalyzes Sequential Formation of Intra-protein Sulfur-to-Methylene Carbon Thioether Bonds

(2015) Tadashi Nakai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PqqD Is a Novel Peptide Chaperone That Forms a Ternary Complex with the RadicalS-Adenosylmethionine Protein PqqE in the Pyrroloquinoline Quinone Biosynthetic Pathway

(2015) John A. Latham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A prevalent peptide-binding domain guides ribosomal natural product biosynthesis

(2015) Brandon J Burkhart et al.   Nature Chemical Biology

Structure and biosynthesis of a macrocyclic peptide containing an unprecedented lysine-to-tryptophan crosslink

(2015) Kelsey R. Schramma et al.   Nature Chemistry

Pathogen roid rage: Cholesterol utilization byMycobacterium tuberculosis

(2014) Matthew F. Wipperman et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Two [4Fe-4S] Clusters Containing Radical SAM Enzyme SkfB Catalyze Thioether Bond Formation during the Maturation of the Sporulation Killing Factor

(2013) Leif Flühe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

X-ray structure of an AdoMet radical activase reveals an anaerobic solution for formylglycine posttranslational modification

(2013) P. J. Goldman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The radical SAM enzyme AlbA catalyzes thioether bond formation in subtilosin A

(2012) Leif Flühe et al.   Nature Chemical Biology

Bioinformatic evidence for a widely distributed, ribosomally produced electron carrier precursor, its maturation proteins, and its nicotinoprotein redox partners

(2011) Daniel H Haft   BMC GENOMICS

Radical S-adenosylmethionine enzymes: Mechanism, control and function

(2011) Martin R. Challand et al.   NATURAL PRODUCT REPORTS

High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism

(2011) Jennifer E. Griffin et al.   PLoS Pathogens

Interaction of PqqE and PqqD in the pyrroloquinoline quinone (PQQ) biosynthetic pathway links PqqD to the radical SAM superfamily

(2010) Stephen R. Wecksler et al.   CHEMICAL COMMUNICATIONS

Characterization of RimO, a New Member of the Methylthiotransferase Subclass of the Radical SAM Superfamily

(2009) Kyung-Hoon Lee et al.   BIOCHEMISTRY

Pyrroloquinoline Quinone Biogenesis: Demonstration That PqqE fromKlebsiella pneumoniaeIs a RadicalS-Adenosyl-l-methionine Enzyme

(2009) Stephen R. Wecksler et al.   BIOCHEMISTRY

A Thiolase of Mycobacterium tuberculosis Is Required for Virulence and Production of Androstenedione and Androstadienedione from Cholesterol

(2009) N. M. Nesbitt et al.   INFECTION AND IMMUNITY

igr Genes and Mycobacterium tuberculosis Cholesterol Metabolism

(2009) J. C. Chang et al.   JOURNAL OF BACTERIOLOGY

The Radical SAM Superfamily

(2008) Perry A. Frey et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Impact of Mutations on the Midpoint Potential of the [4Fe-4S]+1,+2Cluster and on Catalytic Activity in Electron Transfer Flavoprotein-ubiquinone Oxidoreductase (ETF-QO)†

(2007) Robert J. Usselman et al.   BIOCHEMISTRY