Microbial pathogenesis revealed by intravital microscopy: pros, cons and cautions

Evidence that hepatitis B virus replication in mouse cells is limited by the lack of a host cell dependency factor

(2016) Florian A. Lempp et al.   JOURNAL OF HEPATOLOGY

Robust Anti-viral Immunity Requires Multiple Distinct T Cell-Dendritic Cell Interactions

(2015) Sarah Eickhoff et al.   CELL

Immunosurveillance of the Liver by Intravascular Effector CD8 + T Cells

(2015) Luca G. Guidotti et al.   CELL

Spatiotemporally Distinct Interactions with Dendritic Cell Subsets Facilitates CD4+ and CD8+ T Cell Activation to Localized Viral Infection

(2015) Jyh Liang Hor et al.   IMMUNITY

CXCR3 Chemokine Receptor Enables Local CD8+ T Cell Migration for the Destruction of Virus-Infected Cells

(2015) Heather D. Hickman et al.   IMMUNITY

Understanding liver immunology using intravital microscopy

(2015) Pedro Elias Marques et al.   JOURNAL OF HEPATOLOGY

Intravital two-photon imaging of the gastrointestinal tract

(2015) Masha Kolesnikov et al.   JOURNAL OF IMMUNOLOGICAL METHODS

CD11c-Expressing B Cells Are Located at the T Cell/B Cell Border in Spleen and Are Potent APCs

(2015) Anatoly V. Rubtsov et al.   JOURNAL OF IMMUNOLOGY

The Skin Immune Atlas: Three-Dimensional Analysis of Cutaneous Leukocyte Subsets by Multiphoton Microscopy

(2015) Philip L. Tong et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

In vivo imaging and tracking of host–microbiota interactions via metabolic labeling of gut anaerobic bacteria

(2015) Naama Geva-Zatorsky et al.   NATURE MEDICINE

High-resolution in vivo imaging of mouse brain through the intact skull

(2015) Jung-Hoon Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection

(2015) X. Sewald et al.   SCIENCE

Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature

(2015) Elzbieta Kolaczkowska et al.   Nature Communications

Age-Dependent Cell Trafficking Defects in Draining Lymph Nodes Impair Adaptive Immunity and Control of West Nile Virus Infection

(2015) Justin M. Richner et al.   PLoS Pathogens

In Vivo Nonlinear Optical Imaging of Immune Responses: Tissue Injury and Infection

(2014) Yan Zeng et al.   BIOPHYSICAL JOURNAL

Mouse knockout models for HIV-1 restriction factors

(2014) Jan Rehwinkel   CELLULAR AND MOLECULAR LIFE SCIENCES

Generation of improved humanized mouse models for human infectious diseases

(2014) Michael A. Brehm et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Quantum dot–based multiphoton fluorescent pipettes for targeted neuronal electrophysiology

(2014) Bertalan K Andrásfalvy et al.   NATURE METHODS

Adding new dimensions: towards an integrative understanding of HIV-1 spread

(2014) Oliver T. Fackler et al.   NATURE REVIEWS MICROBIOLOGY

An adaptive approach for uniform scanning in multifocal multiphoton microscopy with a spatial light modulator

(2014) Naoya Matsumoto et al.   OPTICS EXPRESS

Dynamic Visualization of Dendritic Cell-Antigen Interactions in the Skin Following Transcutaneous Immunization

(2014) Teerawan Rattanapak et al.   PLoS One

Visualization of Mouse Neuronal Ganglia Infected by Herpes Simplex Virus 1 (HSV-1) Using Multimodal Non-Linear Optical Microscopy

(2014) Pierre-Alexandre Rochette et al.   PLoS One

In vivo visualization of uterine mast cells by two-photon microscopy

(2014) Franziska Schmerse et al.   REPRODUCTION

Antiretroviral restriction factors in mice

(2014) Smita Nair et al.   VIRUS RESEARCH

Insights into Vibrio cholerae Intestinal Colonization from Monitoring Fluorescently Labeled Bacteria

(2014) Yves A. Millet et al.   PLoS Pathogens

In Vivo Two-Photon Microscopy of Single Nerve Endings in Skin

(2014) Mikhail Yuryev et al.   Jove-Journal of Visualized Experiments

Anatomically Restricted Synergistic Antiviral Activities of Innate and Adaptive Immune Cells in the Skin

(2013) Heather D. Hickman et al.   Cell Host & Microbe

Humanized mice for the study of infectious diseases

(2013) Michael A Brehm et al.   CURRENT OPINION IN IMMUNOLOGY

Peripheral Prepositioning and Local CXCL9 Chemokine-Mediated Guidance Orchestrate Rapid Memory CD8+ T Cell Responses in the Lymph Node

(2013) Wolfgang Kastenmüller et al.   IMMUNITY

Luminal Bacteria Recruit CD103+ Dendritic Cells into the Intestinal Epithelium to Sample Bacterial Antigens for Presentation

(2013) Julia Farache et al.   IMMUNITY

Two-Photon Intravital Imaging of Lungs during Anthrax Infection Reveals Long-Lasting Macrophage-Dendritic Cell Contacts

(2013) Daniel Fiole et al.   INFECTION AND IMMUNITY

PD-1 promotes immune exhaustion by inducing antiviral T cell motility paralysis

(2013) Bernd H. Zinselmeyer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Similar uptake but different trafficking and escape routes of reovirus virions and infectious subvirion particles imaged in polarized Madin–Darby canine kidney cells

(2013) Steeve Boulant et al.   MOLECULAR BIOLOGY OF THE CELL

Completion of the entire hepatitis C virus life cycle in genetically humanized mice

(2013) Marcus Dorner et al.   NATURE

Perivascular macrophages mediate neutrophil recruitment during bacterial skin infection

(2013) Arby Abtin et al.   NATURE IMMUNOLOGY

Nucleation of platelets with blood-borne pathogens on Kupffer cells precedes other innate immunity and contributes to bacterial clearance

(2013) Connie H Y Wong et al.   NATURE IMMUNOLOGY

CRISPR interference (CRISPRi) for sequence-specific control of gene expression

(2013) Matthew H Larson et al.   Nature Protocols

Surgical implantation of an abdominal imaging window for intravital microscopy

(2013) Laila Ritsma et al.   Nature Protocols

Three Phases of CD8 T Cell Response in the Lung Following H1N1 Influenza Infection and Sphingosine 1 Phosphate Agonist Therapy

(2013) Melanie P. Matheu et al.   PLoS One

In vivo imaging of alphaherpesvirus infection reveals synchronized activity dependent on axonal sorting of viral proteins

(2013) A. E. Granstedt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adhesion of Neisseria meningitidis to Dermal Vessels Leads to Local Vascular Damage and Purpura in a Humanized Mouse Model

(2013) Keira Melican et al.   PLoS Pathogens

Type I Interferon Programs Innate Myeloid Dynamics and Gene Expression in the Virally Infected Nervous System

(2013) Debasis Nayak et al.   PLoS Pathogens

Shedding-induced gap formation contributes to gut barrier dysfunction in endotoxemia

(2012) Chieh-Wen Lai et al.   Journal of Trauma and Acute Care Surgery

HIV-infected T cells are migratory vehicles for viral dissemination

(2012) Thomas T. Murooka et al.   NATURE

Intravital multiphoton imaging of immune responses in the mouse ear skin

(2012) Jackson LiangYao Li et al.   Nature Protocols

Tissue-resident memory CD8+ T cells continuously patrol skin epithelia to quickly recognize local antigen

(2012) S. Ariotti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV-1 Nef interferes with T-lymphocyte circulation through confined environments in vivo

(2012) B. Stolp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New generation humanized mice for virus research: Comparative aspects and future prospects

(2012) Ramesh Akkina   VIROLOGY

In vivo imaging of virological synapses

(2012) Xaver Sewald et al.   Nature Communications

A Humanized Mouse Model to Study Hepatitis C Virus Infection, Immune Response, and Liver Disease

(2011) Michael L. Washburn et al.   GASTROENTEROLOGY

Intravital imaging of CTLs killing islet cells in diabetic mice

(2011) Ken Coppieters et al.   JOURNAL OF CLINICAL INVESTIGATION

Migration of cytotoxic lymphocytes in cell cycle permits local MHC I–dependent control of division at sites of viral infection

(2011) Silvia S. Kang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chemokines control naive CD8+T cell selection of optimal lymph node antigen presenting cells

(2011) Heather D. Hickman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A simple introduction to multiphoton microscopy

(2011) A. USTIONE et al.   JOURNAL OF MICROSCOPY

Uropathogenic Escherichia coli P and Type 1 Fimbriae Act in Synergy in a Living Host to Facilitate Renal Colonization Leading to Nephron Obstruction

(2011) Keira Melican et al.   PLoS Pathogens

Entry of Bunyaviruses into Mammalian Cells

(2010) Pierre-Yves Lozach et al.   Cell Host & Microbe

Practical intravital two-photon microscopy for immunological research: faster, brighter, deeper

(2010) Tri Giang Phan et al.   IMMUNOLOGY AND CELL BIOLOGY

Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes

(2010) Santiago F Gonzalez et al.   NATURE IMMUNOLOGY

In vivo imaging of infection immunology—4I’s!

(2010) Paul Garside et al.   Seminars in Immunopathology

Helicobacter pylori Immune Escape Is Mediated by Dendritic Cell–Induced Treg Skewing and Th17 Suppression in Mice

(2009) John Y. Kao et al.   GASTROENTEROLOGY

HIV-1 at the immunological and T-lymphocytic virological synapse

(2008) Claudia Haller et al.   BIOLOGICAL CHEMISTRY

The Major Virus-Producing Cell Type during Murine Cytomegalovirus Infection, the Hepatocyte, Is Not the Source of Virus Dissemination in the Host

(2008) Torsten Sacher et al.   Cell Host & Microbe

Bacterial infection-mediated mucosal signalling induces local renal ischaemia as a defence against sepsis

(2008) Keira Melican et al.   CELLULAR MICROBIOLOGY

Gene Therapy Using Adeno-Associated Virus Vectors

(2008) S. Daya et al.   CLINICAL MICROBIOLOGY REVIEWS

Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis

(2008) Jiyun V. Kim et al.   NATURE

Direct priming of antiviral CD8+ T cells in the peripheral interfollicular region of lymph nodes

(2008) Heather D Hickman et al.   NATURE IMMUNOLOGY