Counter-regulatory paracrine actions of FGF-23 and 1,25(OH)2D in macrophages

Klotho interferes with a novel FGF-signalling pathway and insulin/Igf-like signalling to improve longevity and stress resistance in Caenorhabditis elegans

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Expression of Fgf23 in Activated Dendritic Cells and Macrophages in Response to Immunological Stimuli in Mice

(2015) Yuki Masuda et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Regulation of Renal Fibrosis by Macrophage Polarization

(2015) Bixia Pan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The failing heart is a major source of circulating FGF23 via oncostatin M receptor activation

(2015) Manfred Richter et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

1,25-Dihydroxyvitamin D3Promotes High Glucose-Induced M1 Macrophage Switching to M2 via the VDR-PPARγSignaling Pathway

(2015) Xiaoliang Zhang et al.   Biomed Research International

Identification of Cleavage Sites Leading to the Shed Form of the Anti-Aging Protein Klotho

(2014) Ci-Di Chen et al.   BIOCHEMISTRY

Regulation of CYP27B1 and CYP24A1 hydroxylases limits cell-autonomous activation of vitamin D in dendritic cells

(2014) Rhiannon Kundu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Klotho and Phosphate Are Modulators of Pathologic Uremic Cardiac Remodeling

(2014) M. C. Hu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Klotho Gene Deficiency Causes Salt-Sensitive Hypertension via Monocyte Chemotactic Protein-1/CC Chemokine Receptor 2-Mediated Inflammation

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Inflammatory processes in renal fibrosis

(2014) Xiao-Ming Meng et al.   Nature Reviews Nephrology

Roles of phosphate and fibroblast growth factor 23 in cardiovascular disease

(2014) Julia J. Scialla et al.   Nature Reviews Nephrology

Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis

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Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies

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FGF23 is a novel regulator of intracellular calcium and cardiac contractility in addition to cardiac hypertrophy

(2013) Chad D. Touchberry et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

CYP24A1 and CYP27B1 Polymorphisms Modulate Vitamin D Metabolism in Colon Cancer Cells

(2013) E. T. Jacobs et al.   CANCER RESEARCH

Correlation between vitamin D and cardiovascular disease predictors in overweight and obese Koreans

(2013) Misung Kim et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

25(OH) vitamin D suppresses macrophage adhesion and migration by downregulation of ER stress and scavenger receptor A1 in type 2 diabetes

(2013) Amy E. Riek et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Fibroblast growth factor-23: what we know, what we don't know, and what we need to know

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1,25-Dihydroxyvitamin D3 Regulation of Fibroblast Growth Factor-23 Expression in Bone Cells: Evidence for Primary and Secondary Mechanisms Modulated by Leptin and Interleukin-6

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Fibroblast Growth Factor 23 and Inflammation in CKD

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Vitamin D Therapy and Cardiac Structure and Function in Patients With Chronic Kidney Disease

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Fibroblast growth factor 23 inhibits extrarenal synthesis of 1,25-dihydroxyvitamin D in human monocytes

(2012) Justine Bacchetta et al.   JOURNAL OF BONE AND MINERAL RESEARCH

A Comparative Transcriptome Analysis Identifying FGF23 Regulated Genes in the Kidney of a Mouse CKD Model

(2012) Bing Dai et al.   PLoS One

Fibroblast Growth Factor 23 (FGF23) and Alpha-Klotho Stimulate Osteoblastic MC3T3.E1 Cell Proliferation and Inhibit Mineralization

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Oncostatin M Is a Major Mediator of Cardiomyocyte Dedifferentiation and Remodeling

(2011) Thomas Kubin et al.   Cell Stem Cell

Conditional deletion of Pkd1 in osteocytes disrupts skeletal mechanosensing in mice

(2011) Zhousheng Xiao et al.   FASEB JOURNAL

FGF23 induces left ventricular hypertrophy

(2011) Christian Faul et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophages in Renal Disease

(2011) Y. Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

FGF-23 Associates with Death, Cardiovascular Events, and Initiation of Chronic Dialysis

(2011) J. Kendrick et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease

(2011) Tamara Isakova et al.   KIDNEY INTERNATIONAL

'Dem bones' are made for more than walking

(2011) L Darryl Quarles   NATURE MEDICINE

ADAM-17: the enzyme that does it all

(2010) Monika Gooz   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Klotho Deficiency Causes Vascular Calcification in Chronic Kidney Disease

(2010) M. C. Hu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Initial FGF23-Mediated Signaling Occurs in the Distal Convoluted Tubule

(2009) E. G. Farrow et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Fibroblast Growth Factor 23 and Mortality among Patients Undergoing Hemodialysis

(2008) Orlando M. Gutiérrez et al.   NEW ENGLAND JOURNAL OF MEDICINE

Unexpected actions of vitamin D: new perspectives on the regulation of innate and adaptive immunity

(2008) John S Adams et al.   Nature clinical practice. Endocrinology & metabolism