Quantifying the magnitude of the oxygen artefact inherent in culturing airway cells under atmospheric oxygen versus physiological levels

Flavonoid Fraction of Orange and Bergamot Juices Protect Human Lung Epithelial Cells from Hydrogen Peroxide-Induced Oxidative Stress

(2015) Nadia Ferlazzo et al.   Evidence-based Complementary and Alternative Medicine

In Vitro Multiparameter Assay Development Strategy toward Differentiating Macrophage Responses to Inhaled Medicines

(2015) Ewelina Hoffman et al.   MOLECULAR PHARMACEUTICS

Knockdown of Glutamate Cysteine Ligase Catalytic Subunit by siRNA Causes the Gold Nanoparticles-Induced Cytotoxicity in Lung Cancer Cells

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To be or not to be? Examples of incorrect identification of autophagic compartments in conventional transmission electron microscopy of mammalian cells

(2014) Eeva-Liisa Eskelinen   Autophagy

Cytotoxicity and genotoxicity of nano - and microparticulate copper oxide: role of solubility and intracellular bioavailability

(2014) Annetta Semisch et al.   Particle and Fibre Toxicology

Activation of Nrf2-Antioxidant Response Element Mediated Glutamate Cysteine Ligase Expression in Hepatoma Cell line by Homocysteine

(2013) Monireh Mani et al.   Hepatitis Monthly

Gold nanoparticles trigger apoptosis and necrosis in lung cancer cells with low intracellular glutathione

(2013) Min Liu et al.   JOURNAL OF NANOPARTICLE RESEARCH

Mitochondrial-derived reactive oxygen species (ROS) play a causal role in aging-related intervertebral disc degeneration

(2013) Luigi A. Nasto et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Quantitative Proteomics Reveals Oxygen-Dependent Changes in Neuronal Mitochondria Affecting Function and Sensitivity to Rotenone

(2013) Lance Villeneuve et al.   JOURNAL OF PROTEOME RESEARCH

We need answers

(2013) Ratna Tantra et al.   Nature Nanotechnology

Broaden the discussion

(2013) Bengt Fadeel et al.   Nature Nanotechnology

Oxygen Tension Modulates Differentiation and Primary Macrophage Functions in the Human Monocytic THP-1 Cell Line

(2013) Ana Cristina G. Grodzki et al.   PLoS One

The modality of cell–particle interactions drives the toxicity of nanosized CuO and TiO2 in human alveolar epithelial cells

(2013) Elisa Moschini et al.   TOXICOLOGY LETTERS

Join the dialogue

(2012) Françoise Schrurs et al.   Nature Nanotechnology

Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity

(2012) Stephan T Stern et al.   Particle and Fibre Toxicology

Atmospheric Oxygen Inhibits Growth and Differentiation of Marrow-Derived Mouse Mesenchymal Stem Cells via a p53-Dependent Mechanism: Implications for Long-Term Culture Expansion

(2012) Siddaraju V. Boregowda et al.   STEM CELLS

Molecular Responses of Human Lung Epithelial Cells to the Toxicity of Copper Oxide Nanoparticles Inferred from Whole Genome Expression Analysis

(2011) Nobutaka Hanagata et al.   ACS Nano

Why is the partial oxygen pressure of human tissues a crucial parameter? Small molecules and hypoxia

(2011) Aude Carreau et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Association of Glutathione Level and Cytotoxicity of Gold Nanoparticles in Lung Cancer Cells

(2011) Yunxue Zhao et al.   Journal of Physical Chemistry C

Ups and downs of cellular uptake

(2011) Dominique Lison et al.   Nature Nanotechnology

Oxygen matters: tissue culture oxygen levels affect mitochondrial function and structure as well as responses to HIV viroproteins

(2011) L M Tiede et al.   Cell Death & Disease

Nanotoxicology: a perspective and discussion of whether or not in vitro testing is a valid alternative

(2010) Martin J. D. Clift et al.   ARCHIVES OF TOXICOLOGY

Genotoxic potential of copper oxide nanoparticles in human lung epithelial cells

(2010) Maqusood Ahamed et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Oxygen Tension Modulates Acetaminophen-Induced Mitochondrial Oxidant Stress and Cell Injury in Cultured Hepatocytes

(2010) Hui-Min Yan et al.   TOXICOLOGICAL SCIENCES

Safety assessment for nanotechnology and nanomedicine: concepts of nanotoxicology

(2009) G. Oberdörster   JOURNAL OF INTERNAL MEDICINE

Association of reactive oxygen species levels and radioresistance in cancer stem cells

(2009) Maximilian Diehn et al.   NATURE

Hypoxia inducible factors regulate pluripotency and proliferation in human embryonic stem cells cultured at reduced oxygen tensions

(2009) Catherine E Forristal et al.   REPRODUCTION

Nrf2 protects against airway disorders

(2009) Hye-Youn Cho et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Copper Oxide Nanoparticles Are Highly Toxic: A Comparison between Metal Oxide Nanoparticles and Carbon Nanotubes

(2008) Hanna L. Karlsson et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Oxygen sensors in context

(2007) Jeremy P.T. Ward   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS