Article
Virology
Diego C. Carneiro, Jessica D. Sousa, Joana P. Monteiro-Cunha
Summary: The COVID-19 pandemic has caused significant social and economic disruptions, prompting a global effort to develop effective vaccines. Designing and developing vaccines involves multiple stages, including selecting appropriate platforms, conducting clinical trials, and scaling up production. The world is facing various challenges in combating the pandemic, requiring collaborative efforts to overcome them.
Review
Microbiology
Alejandro Pascual-Iglesias, Javier Canton, Ana Maria Ortega-Prieto, Jose M. Jimenez-Guardeno, Jose Angel Regla-Nava
Summary: The review summarizes the main approaches for vaccine development against SARS-CoV-2, focusing on comparing authorized vaccines in terms of their immunogenicity, efficacy in preventing severe disease, adverse side effects, protection, and ability to cope with emergent variants.
Review
Medicine, General & Internal
Md Tanveer Adil, Rumana Rahman, Douglas Whitelaw, Vigyan Jain, Omer Al-Taan, Farhan Rashid, Aruna Munasinghe, Periyathambi Jambulingam
Summary: SARS-CoV-2, the virus responsible for COVID-19, has caused a global pandemic with high mortality rates. Treatment is primarily supportive, and preventive strategies focus on reducing transmission through contact tracing and hygiene practices.
POSTGRADUATE MEDICAL JOURNAL
(2021)
Review
Microbiology
Maria Karoliny da Silva Torres, Carlos David Araujo Bichara, Maria de Nazare do Socorro de Almeida, Mariana Cayres Vallinoto, Maria Alice Freitas Queiroz, Izaura Maria Vieira Cayres Vallinoto, Eduardo Jose Melo dos Santos, Carlos Alberto Marques de Carvalho, Antonio Carlos R. Vallinoto
Summary: This article conducts an extensive literature review on the impact of SARS-CoV-2 pandemic in terms of biology, sociology, genetics, diagnostics, therapeutics, immunology, and socioeconomics. It aims to provide a comprehensive understanding of the major aspects related to the ongoing pandemic.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Immunology
Priyanka Shah, Gabriela A. Canziani, Erik P. Carter, Irwin Chaiken
Summary: Research suggests that while current focus is on studying the S1 receptor-binding domain in COVID-19 vaccines and therapies, exploring the potential benefits of the more conserved S2 subunit should not be overlooked. Utilizing S2 in treatments and vaccines may enhance the neutralizing potential of antibodies, strengthen memory B-cell and T-cell responses.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Multidisciplinary Sciences
Xiao Xiao, Chris Newman, Christina D. Buesching, David W. Macdonald, Zhao-Min Zhou
Summary: The study documents the sale of 47,381 individuals from 38 species in Wuhan's markets, noting the absence of pangolins and bats which supports the theory that they are not the source of the COVID-19 pandemic. China implemented a temporary ban on wildlife trade and a permanent ban on eating and trading terrestrial wild animals to protect human health, address past inconsistencies, and benefit global biodiversity conservation and animal welfare.
SCIENTIFIC REPORTS
(2021)
Review
Public, Environmental & Occupational Health
Sazada Siddiqui, Heba Waheeb Saeed Alhamdi, Huda Ahmed Alghamdi
Summary: COVID-19 is highly contagious and has caused major disruptions around the world. Prevention is crucial through measures such as self-isolation and vaccination.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Immunology
Donald J. Alcendor, Patricia Matthews-Juarez, Duane Smoot, James E. K. Hildreth, Kimberly Lamar, Mohammad Tabatabai, Derek Wilus, Paul D. Juarez
Summary: The incidence of COVID-19 breakthrough infections has increased due to the dominance of the Delta and Omicron variants. Breakthrough infections pose a continuing threat to the unvaccinated, and factors such as advanced age, underlying comorbidities, waning immune protection, and viral variants contribute to their occurrence.
Review
Biochemistry & Molecular Biology
Pravas Kumar Baral, Jiang Yin, Michael N. G. James
Summary: Researchers worldwide are working on developing prophylactic and therapeutic interventions to combat the COVID-19 crisis, with a focus on antibody-based therapies targeting the viral spike protein, particularly monoclonal antibodies.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Multidisciplinary Sciences
Viviane Fongaro Botosso, Soraia Attie Calil Jorge, Renato Mancini Astray, Ana Marcia de Sa Guimaraes, Monica Beatriz Mathor, Patricia dos Santos de Carneiro, Edison Luiz Durigon, Dimas Covas, Danielle Bruna Leal de Oliveira, Ricardo das Neves Oliveira, Durvanei Augusto Maria, Silas Fernandes Eto, Neuza Maria Frazatti Gallina, Giselle Pidde, Carla Cristina Squaiella-Baptistao, Dilza Trevisan Silva, Isadora Maria Villas-Boas, Dayanne Carla Fernandes, Aline Vivian Vatti Auada, Alexandre Campos Banari, Antonio Francisco de Souza Filho, Camila Bianconi, Carla Lilian de Agostini Utescher, Denise Cristina Andre Oliveira, Douglas Oscar Ceolin Mariano, Flavia Ferreira Barbosa, Giuliana Rondon, Josana Kapronezai, Juliana Galvao da Silva, Mauricio Barbugiani Goldfeder, Priscila Comone, Regis Edgar Castilho Junior, Taiana Taina Silva Pereira, Fan Hui Wen, Denise Tambourgi, Ana Marisa Chudzinski-Tavassi
Summary: The new outbreak of COVID-19 has caused millions of deaths worldwide. Efforts are being made to find effective treatments, such as using immunoglobulin from immunized animals or plasma from convalescent patients. Clinical trials using anti-SARS-CoV-2 immunoglobulins from horses immunized with spike protein are underway. Researchers have developed an anti-SARS-CoV-2 equine F(ab ')(2) immunoglobulin that successfully neutralizes the virus, is safe in animal models, and reduces the severity of the disease in a hamster model of SARS-CoV-2 infection.
SCIENTIFIC REPORTS
(2022)
Editorial Material
Geriatrics & Gerontology
Roy L. Soiza, Chiara Scicluna, Emma C. Thomson
Summary: The safety and efficacy of COVID-19 vaccines in older people are crucial for their success, but there is currently a lack of data. While some Phase III trials have made efforts to recruit older people, those with co-morbidities and frailty have still been largely excluded. Older people, their carers, and healthcare professionals will need to make decisions on vaccination acceptance based on limited evidence.
Review
Biochemistry & Molecular Biology
Gang Wang, Ze Xiang, Wei Wang, Zhi Chen
Summary: The ongoing COVID-19 epidemic has seen a slow increase in vaccination rates and the development of treatments and drugs. Additionally, there is growing evidence of preexisting immunity against the SARS-CoV-2 virus in humans, mainly consisting of antibodies and immune cells. Preexisting immunity can help protect against infection, reduce disease severity, and enhance immune response.
JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B
(2022)
Review
Medical Laboratory Technology
Marco Ciotti, Massimo Ciccozzi, Massimo Pieri, Sergio Bernardini
Summary: The article discusses the development of COVID-19 vaccines, the impact of viral variants on transmission and virus antibodies, and methods for measuring vaccine antibody responses. It also emphasizes the importance of using the WHO International Standard to accurately calibrate immunoassays.
CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES
(2022)
Article
Medicine, Research & Experimental
Andrea Nachon-Acosta, Gustavo Martinez-Mier, Victor Flores-Gamboa, Octavio Avila-Mercado, Indira Morales Garcia, Carlos Yoldi-Aguirre, Irais Olivares-Garcia, Maritza de la Paz-roman
Summary: The study aimed to determine the characteristics and outcomes of patients undergoing surgery during the COVID-19 pandemic in a third level reference hospital in Mexico. The results showed that patients with COVID-19 infection had higher postoperative morbidity and mortality rates, with significant associations with respiratory, infection, transfusion, renal function, and other complications.
ARCHIVES OF MEDICAL RESEARCH
(2021)
Article
Immunology
Yifan Li, Melanie Merbah, Suzanne Wollen-Roberts, Bradley Beckman, Thembi Mdluli, Isabella Swafford, Sandra V. Mayer, Jocelyn King, Courtney Corbitt, Jeffrey R. Currier, Heather Liu, Allahna Esber, Suteeraporn Pinyakorn, Ajay Parikh, Leilani V. Francisco, Nittaya Phanuphak, Jonah Maswai, John Owuoth, Hannah Kibuuka, Michael Iroezindu, Emmanuel Bahemana, Sandhya Vasan, Julie A. Ake, Kayvon Modjarrad, Gregory Gromowski, Dominic Paquin-Proulx, Morgane Rolland
Summary: Prior immune responses to coronaviruses may impact the human response to SARS-CoV-2. There were differences in antibody responses to SARS-CoV-2 and other coronaviruses between participants from Africa and Thailand. These findings have implications for the distribution of vaccines and monoclonal antibodies globally.
EMERGING INFECTIOUS DISEASES
(2022)
Article
Energy & Fuels
Shashank Saini, Ashish A. Kadam, Vivek Kumar, Kirtiraj K. Gaikwad, Surendra Pratap Singh, Dharm Dutt
Summary: Rice straw can be converted into paperboard and food-serving bowls through the process of refiner mechanical pulping, with improved water and grease resistance. Utilizing rice straw for value-added products holds promise in reducing air pollution, decreasing plastic disposables, and promoting entrepreneurship in rural areas.
BIOMASS CONVERSION AND BIOREFINERY
(2023)
Article
Energy & Fuels
Afreen Sultana, Mohammed Wasim Siddiqui, Kirtiraj K. Gaikwad
Summary: A novel ZIF-8/zeolite composite was developed to effectively adsorb ethylene in food packaging industry, utilizing the distinctive porous nanostructure and stability of ZIF-8.
BIOMASS CONVERSION AND BIOREFINERY
(2022)
Article
Food Science & Technology
Pardeep Kumar, Lokesh Kumar, Rohit Tanwar, Suman Singh, Kirtiraj K. Gaikwad
Summary: The present study investigated the effects of a guar gum based edible coating containing citric acid and mint leaves extract on ber fruit. Results showed that a coating with 10% mint leaves extract exhibited high antimicrobial and antioxidant activities, reducing respiration rate, TSS, and weight loss during storage, and improving the firmness of the fruit. The sensory aspects of the coating also improved with higher mint leaves extract content.
JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION
(2023)
Article
Food Science & Technology
Harshi Singhi, Lokesh Kumar, Preetam Sarkar, Kirtiraj K. Gaikwad
Summary: In order to mitigate the health risks associated with the use of plastic films for food preservation, new functional films derived from non-toxic and antioxidant biosources need to be developed. This study developed chitosan-based active antioxidant films by incorporating halloysite nanotubes and Citrus limetta pomace extract. The addition of the extract resulted in thicker films with improved elongation ratio and reduced tensile strength. The optimal film with 20% LPE exhibited 80.42% antioxidant properties.
JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION
(2023)
Review
Energy & Fuels
Kirtiraj K. Anushikha, Kirtiraj K. Gaikwad
Summary: The excessive use of non-biodegradable plastics has caused severe environmental pollution and raised ecological concerns. To address this issue, biodegradable and renewable materials, particularly lignin-derived films, have gained significant attention. Lignin, as an abundant aromatic polymer with excellent biodegradability and biocompatibility, holds immense potential for producing functional and sustainable materials as substitutes for plastics. This article reviews the applications of lignin-derived films in food packaging, focusing on their role as UV blockers, antioxidants, and antimicrobial agents. The review also highlights recent advancements in the preparation and advanced applications of lignin-derived film materials, discussing their structural and chemical characteristics, extraction and incorporation techniques, and potential future directions for sustainable and environmentally friendly lignin-derived films.
BIOMASS CONVERSION AND BIOREFINERY
(2023)
Article
Biochemistry & Molecular Biology
Hanuman Singh Dagur, Esmaeil Behmard, Eerappa Rajakumara, Ebrahim Barzegari
Summary: Computational-based screening identified 24-Methylene cycloartanol acetate (24MCA) and sitosterol acetate (SA) from Lagerstroemia speciosa as potential inhibitors of the SARS-CoV-2 virus.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Thermodynamics
Jitendra Kumar, Konala Akhila, Pardeep Kumar, Ram Kumar Deshmukh, Kirtiraj K. Gaikwad
Summary: The lifestyle changes of millennials have brought about a revolution in the food industry. They prefer effortless ready-to-eat or cook meals (RTE) and expect their food to be served hot. Thermochromic materials can be used as temperature indicators on packaging to communicate the temperature of the food inside.
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
(2023)
Article
Food Science & Technology
Konala Akhila, Afreen Sultana, Dakuri Ramakanth, Kirtiraj K. Gaikwad
Summary: With enormous amounts of food being wasted at every level of consumption, the future of food security is in jeopardy. Intelligent colorimetric indicators using natural pigments can help eliminate confusion and communicate the quality of food. This study developed a pH indicator film using anthocyanins extracted from a novel flower source, which showed promising potential as an active and intelligent visual indicator in poultry packaging.
Article
Energy & Fuels
Lokesh Kumar, Shefali Tripathi, Kirtiraj K. K. Gaikwad
Summary: A cactus mucilage-gelatin bio-composite film was made using a solution casting method. The effects of citric acid as a crosslinking agent at different concentrations on the film's moisture sorption characteristics and mechanical properties were studied. Results showed that incorporating citric acid reduced the film's moisture content, swelling ratio, water vapor permeability, and moisture sorption tendency. The film with 0.5% citric acid exhibited the best crystallinity and highest tensile strength, making it suitable for food packaging applications.
BIOMASS CONVERSION AND BIOREFINERY
(2023)
Article
Energy & Fuels
Prachi Jain, Shefali Tripathi, Ram Kumar Deshmukh, Kirtiraj K. Gaikwad, Suman Singh
Summary: In this study, sugarcane bagasse and amla pomace were used to develop packaging paper, with the investigation of the synergistic effect of nanoparticle TiO2 and amla pomace. It was found that the utilization of sugarcane bagasse could bring a sustainable solution for non-wood pulp, while the addition of TiO2 did not significantly affect the mechanical properties of the paper. The water vapor barrier quality and crystallinity of the paper were improved.
BIOMASS CONVERSION AND BIOREFINERY
(2023)
Review
Astronomy & Astrophysics
Lokesh Kumar, Kirtiraj K. Gaikwad
Summary: Since the beginning of space exploration missions, space agencies have been improving the quality of food and nutrition for crew members through advancements in food processing, preservation, and packaging. Different types of space food, such as bite-size food, rehydratable food, thermostabilized food, intermediate moisture food, and irradiated food, are reviewed. The article also highlights the challenges and packaging trends of space food from organizations like DRDO, JAXA, and NASA.
LIFE SCIENCES IN SPACE RESEARCH
(2023)
Article
Food Science & Technology
Bittu Prudhvi Kumar, Dakuri Ramakanth, Konala Akhila, Kirtiraj K. Gaikwad
Summary: A novel non-metallic oxygen scavenging system consisting of 3-hydroxyphenol and potassium carbonate was developed and activated with moisture. The optimum formulation was found to be 1:1 (w/w) ratio of 3-hydroxyphenol and potassium carbonate. The developed system demonstrated efficient oxygen scavenging capacities at different storage temperatures and humidities.
FOOD PACKAGING AND SHELF LIFE
(2023)
Article
Materials Science, Multidisciplinary
Dakuri Ramakanth, Shiva Singh, Shakshi Bhardwaj, Radheesh Sharma Meda, Kirtiraj K. Gaikwad, Pradip K. Maji
Summary: Food scarcity and safety are pressing issues in the modern world. This study investigates the use of environmentally friendly synthesis of polymyrcene to address these concerns. The research demonstrates that the synthesized polymer has an excellent oxygen scavenging capacity when activated by UV light, making it suitable for active food packaging.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Ram Kumar Anushikha, Ram Kumar Deshmukh, Praveen Kumar Kunam, Kirtiraj K. Gaikwad
Summary: This study investigates the potential of incorporating micro-fibrillated cellulose and halloysite nanotubes into guar gum films for active antioxidant food packaging. The results show that the addition of micro-fibrillated cellulose and halloysite nanotubes improves the properties of the films, including thermal stability and antioxidant activity.
SUSTAINABLE CHEMISTRY AND PHARMACY
(2023)
Review
Nanoscience & Nanotechnology
Ram Kumar Deshmukh, Lokman Hakim, Konala Akhila, Dakuri Ramakanth, Kirtiraj K. Gaikwad
Summary: Nano clays have been widely studied and utilized in food packaging due to their ability to enhance physical, chemical, and barrier properties. However, potential toxicity issues from prolonged exposure to nano clays need further investigation and risk assessment.
INTERNATIONAL NANO LETTERS
(2023)
