ESCRT-III and Vps4: a dynamic multipurpose tool for membrane budding and scission

Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology

(2015) Emma L. Clayton et al.   ACTA NEUROPATHOLOGICA

The VPS-20 subunit of the endosomal sorting complex ESCRT-III exhibits an open conformation in the absence of upstream activation

(2015) Amber L. Schuh et al.   BIOCHEMICAL JOURNAL

Relaxation of Loaded ESCRT-III Spiral Springs Drives Membrane Deformation

(2015) Nicolas Chiaruttini et al.   CELL

Heparanase activates the syndecan-syntenin-ALIX exosome pathway

(2015) Bart Roucourt et al.   CELL RESEARCH

Constitutively active ESCRT-II suppresses the MVB-sorting phenotype of ESCRT-0 and ESCRT-I mutants

(2015) Shrawan Kumar Mageswaran et al.   MOLECULAR BIOLOGY OF THE CELL

ESCRTs Cooperate with a Selective Autophagy Receptor to Mediate Vacuolar Targeting of Soluble Cargos

(2015) Xiao-Man Liu et al.   MOLECULAR CELL

ESCRT-III controls nuclear envelope reformation

(2015) Yolanda Olmos et al.   NATURE

Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing

(2015) Marina Vietri et al.   NATURE

Complex archaea that bridge the gap between prokaryotes and eukaryotes

(2015) Anja Spang et al.   NATURE

Vps4 disassembles an ESCRT-III filament by global unfolding and processive translocation

(2015) Bei Yang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Negative membrane curvature catalyzes nucleation of endosomal sorting complex required for transport (ESCRT)-III assembly

(2015) Il-Hyung Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and membrane remodeling activity of ESCRT-III helical polymers

(2015) J. McCullough et al.   SCIENCE

Asymmetric ring structure of Vps4 required for ESCRT-III disassembly

(2015) Christophe Caillat et al.   Nature Communications

Vps4 disassembles an ESCRT-III filament by global unfolding and processive translocation

(2015) Bei Yang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An ESCRT module is required for neuron pruning

(2015) Nicolas Loncle et al.   Scientific Reports

Starvation-Dependent Regulation of Golgi Quality Control Links the TOR Signaling and Vacuolar Protein Sorting Pathways

(2015) Niv Dobzinski et al.   Cell Reports

Super-Resolution Imaging of ESCRT-Proteins at HIV-1 Assembly Sites

(2015) Jens Prescher et al.   PLoS Pathogens

The coordinated action of the MVB pathway and autophagy ensures cell survival during starvation

(2015) Martin Müller et al.   eLife

ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins

(2015) Anna Caballe et al.   eLife

Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments

(2015) Shaogeng Tang et al.   eLife

ESCRTing autophagic clearance of aggregating proteins

(2014) Tor Erik Rusten et al.   Autophagy

Surveillance of Nuclear Pore Complex Assembly by ESCRT-III/Vps4

(2014) Brant M. Webster et al.   CELL

Endocytic Pathways Downregulate the L1-type Cell Adhesion Molecule Neuroglian to Promote Dendrite Pruning in Drosophila

(2014) Heng Zhang et al.   DEVELOPMENTAL CELL

Vfa1 Binds to the N-terminal Microtubule-interacting and Trafficking (MIT) Domain of Vps4 and Stimulates Its ATPase Activity

(2014) Cody J. Vild et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coordinated binding of Vps4 to ESCRT-III drives membrane neck constriction during MVB vesicle formation

(2014) Manuel Alonso Y Adell et al.   JOURNAL OF CELL BIOLOGY

Structural analysis and modeling reveals new mechanisms governing ESCRT-III spiral filament assembly

(2014) Qing-Tao Shen et al.   JOURNAL OF CELL BIOLOGY

The role of the endosomal sorting complexes required for transport (ESCRT) in tumorigenesis

(2014) Claudia Mattissek et al.   MOLECULAR MEMBRANE BIOLOGY

ANCHR mediates Aurora-B-dependent abscission checkpoint control through retention of VPS4

(2014) Sigrid B. Thoresen et al.   NATURE CELL BIOLOGY

Temporal and spatial organization of ESCRT protein recruitment during HIV-1 budding

(2014) M. Bleck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distribution of ESCRT Machinery at HIV Assembly Sites Reveals Virus Scaffolding of ESCRT Subunits

(2014) S. B. Van Engelenburg et al.   SCIENCE

ESCRT Machinery Is Required for Plasma Membrane Repair

(2014) A. J. Jimenez et al.   SCIENCE

Mechanism of Ca2+-triggered ESCRT assembly and regulation of cell membrane repair

(2014) Luana L. Scheffer et al.   Nature Communications

Structure of cellular ESCRT-III spirals and their relationship to HIV budding

(2014) Anil G Cashikar et al.   eLife

Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine

(2013) Benjamin M. Stinson et al.   CELL

Essential N-Terminal Insertion Motif Anchors the ESCRT-III Filament during MVB Vesicle Formation

(2013) Nicholas J. Buchkovich et al.   DEVELOPMENTAL CELL

An ESCRT–spastin interaction promotes fission of recycling tubules from the endosome

(2013) Rachel Allison et al.   JOURNAL OF CELL BIOLOGY

Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles

(2013) Marina Colombo et al.   JOURNAL OF CELL SCIENCE

The Oligomeric State of the Active Vps4 AAA ATPase

(2013) Nicole Monroe et al.   JOURNAL OF MOLECULAR BIOLOGY

Computational Model of Cytokinetic Abscission Driven by ESCRT-III Polymerization and Remodeling

(2012) Natalie Elia et al.   BIOPHYSICAL JOURNAL

The Endosomal Sorting Complex ESCRT-II Mediates the Assembly and Architecture of ESCRT-III Helices

(2012) William Mike Henne et al.   CELL

Nuclear Envelope Budding Enables Large Ribonucleoprotein Particle Export during Synaptic Wnt Signaling

(2012) Sean D. Speese et al.   CELL

ESCRT-III CHMP2A and CHMP3 form variable helical polymersin vitroand act synergistically during HIV-1 budding

(2012) Grégory Effantin et al.   CELLULAR MICROBIOLOGY

The ESCRT machinery

(2012) Oliver Schmidt et al.   CURRENT BIOLOGY

Structural Basis of Molecular Recognition between ESCRT-III-like Protein Vps60 and AAA-ATPase Regulator Vta1 in the Multivesicular Body Pathway

(2012) Zhongzheng Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Syndecan–syntenin–ALIX regulates the biogenesis of exosomes

(2012) Maria Francesca Baietti et al.   NATURE CELL BIOLOGY

Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein

(2012) J. F. Nabhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ESCRT-III Governs the Aurora B-Mediated Abscission Checkpoint Through CHMP4C

(2012) J. G. Carlton et al.   SCIENCE

The chromosomal passenger complex controls the function of endosomal sorting complex required for transport-III Snf7 proteins during cytokinesis

(2012) L. Capalbo et al.   Open Biology

The ESCRT Machinery Is Recruited by the Viral BFRF1 Protein to the Nucleus-Associated Membrane for the Maturation of Epstein-Barr Virus

(2012) Chung-Pei Lee et al.   PLoS Pathogens

ESCRT-III Protein Requirements for HIV-1 Budding

(2011) Eiji Morita et al.   Cell Host & Microbe

Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles

(2011) Bence György et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Frontotemporal Dementia Caused by CHMP2B Mutations

(2011) A. M. Isaacs et al.   Current Alzheimer Research

The P4-ATPase TAT-5 Inhibits the Budding of Extracellular Vesicles in C. elegans Embryos

(2011) Ann M. Wehman et al.   CURRENT BIOLOGY

The ESCRT Pathway

(2011) William M. Henne et al.   DEVELOPMENTAL CELL

Microautophagy of Cytosolic Proteins by Late Endosomes

(2011) Ranjit Sahu et al.   DEVELOPMENTAL CELL

Charged Multivesicular Body Protein 2B (CHMP2B) of the Endosomal Sorting Complex Required for Transport-III (ESCRT-III) Polymerizes into Helical Structures Deforming the Plasma Membrane

(2011) Gilles Bodon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bro1 binding to Snf7 regulates ESCRT-III membrane scission activity in yeast

(2011) Megan Wemmer et al.   JOURNAL OF CELL BIOLOGY

Live-cell visualization of dynamics of HIV budding site interactions with an ESCRT component

(2011) Viola Baumgärtel et al.   NATURE CELL BIOLOGY

Dynamics of ESCRT protein recruitment during retroviral assembly

(2011) Nolwenn Jouvenet et al.   NATURE CELL BIOLOGY

Shaping development with ESCRTs

(2011) Tor Erik Rusten et al.   NATURE CELL BIOLOGY

Host factors involved in retroviral budding and release

(2011) Juan Martin-Serrano et al.   NATURE REVIEWS MICROBIOLOGY

Dynamics of endosomal sorting complex required for transport (ESCRT) machinery during cytokinesis and its role in abscission

(2011) N. Elia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cortical Constriction During Abscission Involves Helices of ESCRT-III-Dependent Filaments

(2011) J. Guizetti et al.   SCIENCE

Exosome Secretion: Molecular Mechanisms and Roles in Immune Responses

(2011) Angélique Bobrie et al.   TRAFFIC

Regulation of Membrane Protein Degradation by Starvation-Response Pathways

(2011) Charles B. Jones et al.   TRAFFIC

ESCRT-II coordinates the assembly of ESCRT-III filaments for cargo sorting and multivesicular body vesicle formation

(2010) David Teis et al.   EMBO JOURNAL

Assembly of the AAA ATPase Vps4 on ESCRT-III

(2010) Anna Shestakova et al.   MOLECULAR BIOLOGY OF THE CELL

The Selective Macroautophagic Degradation of Aggregated Proteins Requires the PI3P-Binding Protein Alfy

(2010) Maria Filimonenko et al.   MOLECULAR CELL

Human ESCRT-III and VPS4 proteins are required for centrosome and spindle maintenance

(2010) E. Morita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ESCRTs and human disease

(2009) Suraj Saksena et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Functional Reconstitution of ESCRT-III Assembly and Disassembly

(2009) Suraj Saksena et al.   CELL

Structure and Function of the ESCRT-II-III Interface in Multivesicular Body Biogenesis

(2009) Young Jun Im et al.   DEVELOPMENTAL CELL

Exosomes: proteomic insights and diagnostic potential

(2009) Richard J Simpson et al.   Expert Review of Proteomics

Herpes Simplex Virus Type 1 Production Requires a Functional ESCRT-III Complex but Is Independent of TSG101 and ALIX Expression

(2009) T. Pawliczek et al.   JOURNAL OF VIROLOGY

Biochemical Analyses of Human IST1 and Its Function in Cytokinesis

(2009) Monika Bajorek et al.   MOLECULAR BIOLOGY OF THE CELL

Membrane scission by the ESCRT-III complex

(2009) Thomas Wollert et al.   NATURE

Structural basis for ESCRT-III protein autoinhibition

(2009) Monika Bajorek et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ExoCarta: A compendium of exosomal proteins and RNA

(2009) Suresh Mathivanan et al.   PROTEOMICS

Ordered Assembly of the ESCRT-III Complex on Endosomes Is Required to Sequester Cargo during MVB Formation

(2008) David Teis et al.   DEVELOPMENTAL CELL

ESCRT proteins in physiology and disease

(2008) Susanne Stuffers et al.   EXPERIMENTAL CELL RESEARCH

Plasma membrane deformation by circular arrays of ESCRT-III protein filaments

(2008) Phyllis I. Hanson et al.   JOURNAL OF CELL BIOLOGY

Biochemical and Structural Studies of Yeast Vps4 Oligomerization

(2008) Malgorzata D. Gonciarz et al.   JOURNAL OF MOLECULAR BIOLOGY

Cryo-EM Structure of Dodecameric Vps4p and Its 2:1 Complex with Vta1p

(2008) Zhiheng Yu et al.   JOURNAL OF MOLECULAR BIOLOGY

In Vitro Budding of Intralumenal Vesicles into Late Endosomes Is Regulated by Alix and Tsg101

(2008) Thomas Falguières et al.   MOLECULAR BIOLOGY OF THE CELL

Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B

(2008) Dong Yang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Differential requirements for Alix and ESCRT-III in cytokinesis and HIV-1 release

(2008) J. G. Carlton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A unique cell division machinery in the Archaea

(2008) A.-C. Lindas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ALIX-CHMP4 interactions in the human ESCRT pathway

(2008) J. McCullough et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Role for the ESCRT System in Cell Division in Archaea

(2008) R. Y. Samson et al.   SCIENCE

Midbody Targeting of the ESCRT Machinery by a Noncanonical Coiled Coil in CEP55

(2008) H. H. Lee et al.   SCIENCE

Helical Structures of ESCRT-III Are Disassembled by VPS4

(2008) S. Lata et al.   SCIENCE

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE

Structure and Disassembly of Filaments Formed by the ESCRT-III Subunit Vps24

(2008) Sara Ghazi-Tabatabai et al.   STRUCTURE

Nucleotide-Dependent Conformational Changes and Assembly of the AAA ATPase SKD1/VPS4B

(2008) Michio Inoue et al.   TRAFFIC

Evolution of the Multivesicular Body ESCRT Machinery; Retention Across the Eukaryotic Lineage

(2008) Ka Fai Leung et al.   TRAFFIC

Ist1 Regulates Vps4 Localization and Assembly

(2007) Christian Dimaano et al.   MOLECULAR BIOLOGY OF THE CELL