ASIC and ENaC type sodium channels: conformational states and the structures of the ion selectivity filters

Molecular basis of ion permeability in a voltage‐gated sodium channel

(2016) Claire E Naylor et al.   EMBO JOURNAL

Epithelial sodium channel (ENaC) family: Phylogeny, structure–function, tissue distribution, and associated inherited diseases

(2016) Israel Hanukoglu et al.   GENE

Voltage-Gated Potassium Channels: A Structural Examination of Selectivity and Gating

(2016) Dorothy M. Kim et al.   Cold Spring Harbor Perspectives in Biology

CHEXVIS: a tool for molecular channel extraction and visualization

(2015) Talha Bin Masood et al.   BMC BIOINFORMATICS

Functional Roles of Clusters of Hydrophobic and Polar Residues in the Epithelial Na+Channel Knuckle Domain

(2015) Jingxin Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intracellular Na+Regulates Epithelial Na+Channel Maturation

(2015) Elisa Heidrich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The hitchhiker’s guide to the voltage-gated sodium channel galaxy

(2015) Christopher A. Ahern et al.   JOURNAL OF GENERAL PHYSIOLOGY

Voltage-Gated Sodium Channels: Structure, Function, Pharmacology, and Clinical Indications

(2015) Manuel de Lera Ruiz et al.   JOURNAL OF MEDICINAL CHEMISTRY

Acid-sensing ion channels in gastrointestinal function

(2015) Peter Holzer   NEUROPHARMACOLOGY

Genetic exploration of the role of acid-sensing ion channels

(2015) Shing-Hong Lin et al.   NEUROPHARMACOLOGY

Biophysical properties of acid-sensing ion channels (ASICs)

(2015) Stefan Gründer et al.   NEUROPHARMACOLOGY

Epithelial Sodium Transport and Its Control by Aldosterone: The Story of Our Internal Environment Revisited

(2015) Bernard C. Rossier et al.   PHYSIOLOGICAL REVIEWS

X-Ray Structure of Acid-Sensing Ion Channel 1–Snake Toxin Complex Reveals Open State of a Na+-Selective Channel

(2014) Isabelle Baconguis et al.   CELL

Lithium: A review of pharmacology, clinical uses, and toxicity

(2014) Ramadhan Oruch et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Conserved charged residues at the surface and interface of epithelial sodium channel subunits - roles in cell surface expression and the sodium self-inhibition response

(2014) Oded Edelheit et al.   FEBS Journal

Ion conduction and selectivity in acid-sensing ion channel 1

(2014) Lei Yang et al.   JOURNAL OF GENERAL PHYSIOLOGY

Actin directly interacts with different membrane channel proteins and influences channel activities: AQP2 as a model

(2013) Sei Sasaki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The bile acid-sensitive ion channel (BASIC), the ignored cousin of ASICs and ENaC

(2013) Dominik Wiemuth et al.   Channels

Structure and function of voltage-gated sodium channels at atomic resolution

(2013) William A. Catterall   EXPERIMENTAL PHYSIOLOGY

Molecular determinants of desensitization in an ENaC/degenerin channel

(2013) Sophie Roy et al.   FASEB JOURNAL

Pharmacological and electrophysiological characterization of the human bile acid-sensitive ion channel (hBASIC)

(2013) Cathérine M. T. Lefèvre et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Venom toxins in the exploration of molecular, physiological and pathophysiological functions of acid-sensing ion channels

(2013) Anne Baron et al.   TOXICON

The Genetic Architecture of Degenerin/Epithelial Sodium Channels in Drosophila

(2013) Kathleen M. Zelle et al.   G3-Genes Genomes Genetics

Characterization of a novel splice variant of δ ENaC subunit in human lungs

(2012) Run-Zhen Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

δ ENaC: a novel divergent amiloride-inhibitable sodium channel

(2012) Hong-Long Ji et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Software tools for identification, visualization and analysis of protein tunnels and channels

(2012) Jan Brezovsky et al.   BIOTECHNOLOGY ADVANCES

Epithelial Na+ channel regulation by cytoplasmic and extracellular factors

(2012) Ossama B. Kashlan et al.   EXPERIMENTAL CELL RESEARCH

Impact of Recovery from Desensitization on Acid-sensing Ion Channel-1a (ASIC1a) Current and Response to High Frequency Stimulation

(2012) Tianbo Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural plasticity and dynamic selectivity of acid-sensing ion channel–spider toxin complexes

(2012) Isabelle Baconguis et al.   NATURE

Insight into DEG/ENaC Channel Gating from Genetics and Structure

(2012) Amy L. Eastwood et al.   PHYSIOLOGY

Structure of the Acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1

(2012) Roger J.P. Dawson et al.   Nature Communications

Regulation and dysregulation of epithelial Na+ channels

(2011) Lawrence G. Palmer et al.   Clinical and Experimental Nephrology

Epithelial sodium channels (ENaC) are uniformly distributed on motile cilia in the oviduct and the respiratory airways

(2011) Yehoshua Enuka et al.   HISTOCHEMISTRY AND CELL BIOLOGY

A Study of the Hydration of the Alkali Metal Ions in Aqueous Solution

(2011) Johan Mähler et al.   INORGANIC CHEMISTRY

The Interaction between Two Extracellular Linker Regions Controls Sustained Opening of Acid-sensing Ion Channel 1

(2011) Andreas Springauf et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Atomic Force Microscopy Reveals the Architecture of the Epithelial Sodium Channel (ENaC)

(2011) Andrew P. Stewart et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heteromeric Acid-Sensing Ion Channels (ASICs) Composed of ASIC2b and ASIC1a Display Novel Channel Properties and Contribute to Acidosis-Induced Neuronal Death

(2011) T. W. Sherwood et al.   JOURNAL OF NEUROSCIENCE

Mechanism of Ion Permeation and Selectivity in a Voltage Gated Sodium Channel

(2011) Ben Corry et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Neocortical levels of lithium are increased in bipolar disorder

(2011) A L Friedlich   MOLECULAR PSYCHIATRY

The crystal structure of a voltage-gated sodium channel

(2011) Jian Payandeh et al.   NATURE

Proton-Binding Sites of Acid-Sensing Ion Channel 1

(2011) Hiroshi Ishikita   PLoS One

Outlines of the pore in open and closed conformations describe the gating mechanism of ASIC1

(2011) Tianbo Li et al.   Nature Communications

Two residues in the extracellular domain convert a nonfunctional ASIC1 into a proton-activated channel

(2010) Tianbo Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A Combined Computational and Functional Approach Identifies New Residues Involved in pH-dependent Gating of ASIC1a

(2010) Luz Angélica Liechti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular Allosteric Regulatory Subdomain within the γ Subunit of the Epithelial Na+Channel

(2010) Katie L. Winarski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Asn415in the β11-β12 Linker Decreases Proton-dependent Desensitization of ASIC1

(2010) Tianbo Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Use of Venom Peptides to Probe Ion Channel Structure and Function

(2010) Sébastien Dutertre et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Leu85in the β1-β2 Linker of ASIC1 Slows Activation and Decreases the Apparent Proton Affinity by Stabilizing a Closed Conformation

(2010) Tianbo Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Truncated beta epithelial sodium channel (ENaC) subunits responsible for multi-system pseudohypoaldosteronism support partial activity of ENaC

(2010) Oded Edelheit et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Pore architecture and ion sites in acid-sensing ion channels and P2X receptors

(2009) Eric B. Gonzales et al.   NATURE

Inherent Dynamics of the Acid-Sensing Ion Channel 1 Correlates with the Gating Mechanism

(2009) Huaiyu Yang et al.   PLOS BIOLOGY

Simple chordates exhibit a proton-independent function of acid-sensing ion channels

(2008) Tatjana Coric et al.   FASEB JOURNAL

Extracellular Protons Regulate Human ENaC by Modulating Na+Self-inhibition

(2008) Daniel M. Collier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction of the Aromatics Tyr-72/Trp-288 in the Interface of the Extracellular and Transmembrane Domains Is Essential for Proton Gating of Acid-sensing Ion Channels

(2008) Tianbo Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Renin–aldosterone response, urinary Na/K ratio and growth in pseudohypoaldosteronism patients with mutations in epithelial sodium channel (ENaC) subunit genes

(2008) Aaron Hanukoglu et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY