Pigment epithelium–derived factor restoration increases bone mass and improves bone plasticity in a model of osteogenesis imperfecta type VI via Wnt3a blockade

Osteogenesis imperfecta

(2016) Antonella Forlino et al.   LANCET

Restoration of the serum level of SERPINF1 does not correct the bone phenotype in Serpinf1 null mice

(2016) Abbhirami Rajagopal et al.   MOLECULAR GENETICS AND METABOLISM

Pigment Epithelium Derived Factor Suppresses Expression of Sost/Sclerostin by Osteocytes: Implication for Its Role in Bone Matrix Mineralization

(2015) Feng Li et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Mutation spectrum ofCOL1A1andCOL1A2genes in Indian patients with osteogenesis imperfecta

(2014) Joshi Stephen et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Pigment Epithelium-Derived Factor (PEDF) Suppresses IL-1β-Mediated c-Jun N-Terminal Kinase (JNK) Activation to Improve Hepatocyte Insulin Signaling

(2014) Arijeet K. Gattu et al.   ENDOCRINOLOGY

A NovelIFITM5Mutation in Severe Atypical Osteogenesis Imperfecta Type VI Impairs Osteoblast Production of Pigment Epithelium-Derived Factor

(2014) Charles R Farber et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Clinical and molecular analysis in families with autosomal recessive osteogenesis imperfecta identifies mutations in five genes and suggests genotype-phenotype correlations

(2013) José A. Caparrós-Martin et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Determination of mesenchymal stem cell fate by pigment epithelium-derived factor (PEDF) results in increased adiposity and reduced bone mineral content

(2013) Arijeet K. Gattu et al.   FASEB JOURNAL

A Mouse Model for Human Osteogenesis Imperfecta Type VI

(2013) Rosalind Bogan et al.   JOURNAL OF BONE AND MINERAL RESEARCH

New Genes in Bone Development: What's New in Osteogenesis Imperfecta

(2013) Joan C. Marini et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Pigment Epithelium-Derived Factor Enhances Differentiation and Mineral Deposition of Human Mesenchymal Stem Cells

(2013) Feng Li et al.   STEM CELLS

A co-occurrence of osteogenesis imperfecta type VI and cystinosis

(2012) Tracy Tucker et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Lack of Circulating Pigment Epithelium-Derived Factor Is a Marker of Osteogenesis Imperfecta Type VI

(2012) Frank Rauch et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Study of autosomal recessive osteogenesis imperfecta in Arabia reveals a novel locus defined byTMEM38Bmutation

(2012) Ranad Shaheen et al.   JOURNAL OF MEDICAL GENETICS

Secreted and Transmembrane Wnt Inhibitors and Activators

(2012) C.-M. Cruciat et al.   Cold Spring Harbor Perspectives in Biology

Exome Sequencing Identifies Truncating Mutations in Human SERPINF1 in Autosomal-Recessive Osteogenesis Imperfecta

(2011) Jutta Becker et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Pigment Epithelium-Derived Factor Regulates Early Pancreatic Fibrotic Responses and Suppresses the Profibrotic Cytokine Thrombospondin-1

(2011) John C. Schmitz et al.   AMERICAN JOURNAL OF PATHOLOGY

Mutations in SERPINF1 cause osteogenesis imperfecta type VI

(2011) Erica P Homan et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Lack of expression ofSERPINF1, the gene coding for pigment epithelium-derived factor, causes progressively deforming osteogenesis imperfecta with normal type I collagen

(2011) Giacomo Venturi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Identification of a Novel Inhibitor of the Canonical Wnt Pathway

(2011) K. Park et al.   MOLECULAR AND CELLULAR BIOLOGY

Wnt Antagonists Bind through a Short Peptide to the First β-Propeller Domain of LRP5/6

(2011) Eric Bourhis et al.   STRUCTURE

Dual delivery of VEGF and MCP-1 to support endothelial cell transplantation for therapeutic vascularization

(2010) Steven M. Jay et al.   BIOMATERIALS

Guidelines for assessment of bone microstructure in rodents using micro-computed tomography

(2010) Mary L Bouxsein et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Pigment epithelium-derived factor suppresses adipogenesis via inhibition of the MAPK/ERK pathway in 3T3-L1 preadipocytes

(2009) Min Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

PEDF regulates osteoclasts via osteoprotegerin and RANKL

(2009) Toru Akiyama et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pigment Epithelium-Derived Factor Contributes to Insulin Resistance in Obesity

(2009) Seamus Crowe et al.   Cell Metabolism

Canonical Wnts function as potent regulators of osteogenesis by human mesenchymal stem cells

(2009) Guizhong Liu et al.   JOURNAL OF CELL BIOLOGY

Ethanol Exposure Depletes Hepatic Pigment Epithelium-Derived Factor, a Novel Lipid Regulator

(2008) Chuhan Chung et al.   GASTROENTEROLOGY

Wnt signaling controls the fate of mesenchymal stem cells

(2008) Ling Ling et al.   GENE