Inhibitors of pendrin anion exchange identified in a small molecule screen increase airway surface liquid volume in cystic fibrosis

Pendrin localizes to the adrenal medulla and modulates catecholamine release

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The Relationship of Mucus Concentration (Hydration) to Mucus Osmotic Pressure and Transport in Chronic Bronchitis

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The Role of Pendrin in Renal Physiology

(2015) Susan M. Wall et al.   Annual Review of Physiology

Airway hydration and COPD

(2015) Arunava Ghosh et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Strategies targeting the IL-4/IL-13 axes in disease

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IL-4 and IL-13 signaling in allergic airway disease

(2015) Naina Gour et al.   CYTOKINE

Expression ofPOSTN,IL-4, andIL-13in Chronic Rhinosinusitis with Nasal Polyps

(2015) Jaroslaw Milonski et al.   DNA AND CELL BIOLOGY

The airway microbiome in patients with severe asthma: Associations with disease features and severity

(2015) Yvonne J. Huang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Increased expression of the epithelial anion transporter pendrin/SLC26A4 in nasal polyps of patients with chronic rhinosinusitis

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Virtual High-Throughput Screening To Identify Novel Activin Antagonists

(2015) Jie Zhu et al.   JOURNAL OF MEDICINAL CHEMISTRY

New IDH1 mutant inhibitors for treatment of acute myeloid leukemia

(2015) Ujunwa C Okoye-Okafor et al.   Nature Chemical Biology

Epithelial Anion Transporter Pendrin Contributes to Inflammatory Lung Pathology in Mouse Models of Bordetella pertussis Infection

(2014) Karen M. Scanlon et al.   INFECTION AND IMMUNITY

Identification of Pendrin as a Common Mediator for Mucus Production in Bronchial Asthma and Chronic Obstructive Pulmonary Disease

(2014) Isao Nakao et al.   JOURNAL OF IMMUNOLOGY

The Epithelial Anion Transporter Pendrin Is Induced by Allergy and Rhinovirus Infection, Regulates Airway Surface Liquid, and Increases Airway Reactivity and Inflammation in an Asthma Model

(2014) Y. Nakagami et al.   JOURNAL OF IMMUNOLOGY

IL-17A Induces Pendrin Expression and Chloride-Bicarbonate Exchange in Human Bronchial Epithelial Cells

(2014) Kelly M. Adams et al.   PLoS One

Mouse Models for Pendrin-Associated Loss of Cochlear and Vestibular Function

(2013) Philine Wangemann   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Transcriptome sequencing (RNA-Seq) of human endobronchial biopsies: asthmaversuscontrols

(2013) Ching Yong Yick et al.   EUROPEAN RESPIRATORY JOURNAL

Changes in transcriptome of native nasal epithelium expressing F508del-CFTR and intersecting data from comparable studies

(2013) Luka A Clarke et al.   RESPIRATORY RESEARCH

New Pulmonary Therapies Directed at Targets Other than CFTR

(2013) S. H. Donaldson et al.   Cold Spring Harbor Perspectives in Medicine

How the airway smooth muscle in cystic fibrosis reacts in proinflammatory conditions: implications for airway hyper-responsiveness and asthma in cystic fibrosis

(2013) Sarah McCuaig et al.   Lancet Respiratory Medicine

Structure-Based Discovery of Substituted 4,5′-Bithiazoles as Novel DNA Gyrase Inhibitors

(2012) Matjaž Brvar et al.   JOURNAL OF MEDICINAL CHEMISTRY

Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung

(2012) Alejandro A. Pezzulo et al.   NATURE

Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction

(2012) F. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Periciliary Brush Promotes the Lung Health by Separating the Mucus Layer from Airway Epithelia

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Expression of Pendrin Periostin in Allergic Rhinitis Chronic Rhinosinusitis

(2012) Akihiro Ishida et al.   ALLERGOLOGY INTERNATIONAL

Pendrin Function in Airway Epithelia

(2011) Charity Nofziger et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The Role of Pendrin in the Development of the Murine Inner Ear

(2011) Philine Wangemann   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Hyperviscous airway periciliary and mucous liquid layers in cystic fibrosis measured by confocal fluorescence photobleaching

(2011) Nico Derichs et al.   FASEB JOURNAL

Inflammatory response in rat lungs with recurrent exposure to welding fumes

(2011) Jung-Hwa Oh et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Interleukin-13 Promotes Susceptibility to Chlamydial Infection of the Respiratory and Genital Tracts

(2011) Kelly L. Asquith et al.   PLoS Pathogens

Virtual Screening to Identify Novel Antagonists for the G Protein-Coupled NK3Receptor

(2010) Werner J. Geldenhuys et al.   JOURNAL OF MEDICINAL CHEMISTRY

CFTR-Adenylyl Cyclase I Association Responsible for UTP Activation of CFTR in Well-Differentiated Primary Human Bronchial Cell Cultures

(2010) Wan Namkung et al.   MOLECULAR BIOLOGY OF THE CELL

Airway Mucus Function and Dysfunction

(2010) John V. Fahy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification of potential biomarkers from gene expression profiles in rat lungs intratracheally instilled with C60 fullerenes

(2010) Katsuhide Fujita et al.   TOXICOLOGY

Airway surface liquid depth measured in ex vivo fragments of pig and human trachea: dependence on Na+ and Cl− channel function

(2009) Yuanlin Song et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Biomarkers of lung damage associated with tobacco smoke in induced sputum

(2009) Alessia Comandini et al.   RESPIRATORY MEDICINE

CFTR Delivery to 25% of Surface Epithelial Cells Restores Normal Rates of Mucus Transport to Human Cystic Fibrosis Airway Epithelium

(2009) Liqun Zhang et al.   PLOS BIOLOGY

The Slc26a4 transporter functions as an electroneutral Cl−/I−/HCO3−exchanger: role of Slc26a4 and Slc26a6 in I−and HCO3−secretion and in regulation of CFTR in the parotid duct

(2008) Nikolay Shcheynikov et al.   JOURNAL OF PHYSIOLOGY-LONDON

Pendred syndrome and iodide transport in the thyroid

(2008) Peter Kopp et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Disease-Specific Gene Expression Profiling in Multiple Models of Lung Disease

(2007) Christina C. Lewis et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE